Quantification of O6-methyl and O6-ethyl deoxyguanosine adducts in C57BL/6N/Tk+/- mice using LC/MS/MS

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 844, Issue 1, 2006, Pages 60-66

  Churchwell, Mona I ^a   Beland, Frederick A ^a   Doerge, Daniel R ^a  

^a NATIONAL CENTER FOR TOXICOLOGICAL RESEARCH   (United States)

Author keywords

DNA adducts; Mass spectrometry; O6 Ethyl 2 deoxyguanosine; O6 Methyl 2 deoxyguanosine

Indexed keywords

ALKYLATION; DNA; ISOTOPES; MASS SPECTROMETRY; MUTAGENS;

ALKYLATING AGENTS; CARCINOGENICITY; DNA ADDUCTS; TANDEM MASS SPECTROMETRY;

CARCINOGENS;

6 O ETHYLDEOXYGUANOSINE; DEOXYGUANOSINE DERIVATIVE; DNA; ETHYLNITROSOUREA; METHYLNITROSOUREA; NUCLEOTIDE; O 6 METHYL 2' DEOXYGUANOSINE; UNCLASSIFIED DRUG; DEOXYGUANOSINE; DRUG DERIVATIVE; O(6) ETHYL 2' DEOXYGUANOSINE; O(6) METHYL 2' DEOXYGUANOSINE; O(6)-ETHYL-2'-DEOXYGUANOSINE; O(6)-METHYL-2'-DEOXYGUANOSINE;

ACCURACY; ANALYTIC METHOD; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARCINOGENICITY; CONTROLLED STUDY; DNA ADDUCT; HYDROLYSIS; ISOTOPE DILUTION ASSAY; LIQUID CHROMATOGRAPHY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ASSAY; SENSITIVITY AND SPECIFICITY; TANDEM MASS SPECTROMETRY; ANIMAL; C57BL MOUSE; CHEMISTRY; ELECTROSPRAY MASS SPECTROMETRY; FEMALE; LIVER; METHODOLOGY; STANDARD; VALIDATION STUDY;

ANIMALIA;

ANIMALS; DEOXYGUANOSINE; FEMALE; LIVER; MALE; MICE; MICE, INBRED C57BL; REFERENCE STANDARDS; SENSITIVITY AND SPECIFICITY; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 33845993890     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2006.06.042     Document Type: Article

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