Specific H+/K+-ATPase inhibitors decreased contractile responses of isolated rat vas deferens

Pharmacological Research

Volumn 54, Issue 6, 2006, Pages 397-405

  Yenişehirli, Aydan ^a   Onur, Rüştü ^b  

^a GAZIOSMANPASA UNIVERSITY   (Turkey)

^b HACETTEPE UNIVERSITY   (Turkey)

Author keywords

Contractility; H+ K+ ATPase; Lansoprazole; Omeprazole; Rat vas deferens; SCH 28080

Indexed keywords

8 BENZYLOXY 2 METHYLIMIDAZO[1,2 A]PYRIDINE 3 ACETONITRILE; ADENOSINE TRIPHOSPHATASE (POTASSIUM); ADENOSINE TRIPHOSPHATASE INHIBITOR; CALCIUM; LANSOPRAZOLE; OMEPRAZOLE; OUABAIN; PHENYLEPHRINE; POTASSIUM; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATASE; VOLTAGE GATED CALCIUM CHANNEL;

ANIMAL TISSUE; ARTICLE; CALCIUM CELL LEVEL; CONTROLLED STUDY; ELECTRIC FIELD; IN VITRO STUDY; MALE; MUSCLE CONTRACTILITY; NONHUMAN; PRIORITY JOURNAL; RAT; VAS DEFERENS;

2-PYRIDINYLMETHYLSULFINYLBENZIMIDAZOLES; ADRENERGIC ALPHA-AGONISTS; ANIMALS; CALCIUM; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTRIC STIMULATION; ENZYME INHIBITORS; H(+)-K(+)-EXCHANGING ATPASE; IMIDAZOLES; MALE; MUSCLE CONTRACTION; MUSCLE, SMOOTH; OMEPRAZOLE; OUABAIN; PHENYLEPHRINE; POTASSIUM; RATS; RATS, SPRAGUE-DAWLEY; VAS DEFERENS;

EID: 33845986335     PISSN: 10436618     EISSN: 10961186     Source Type: Journal    
DOI: 10.1016/j.phrs.2006.07.005     Document Type: Article

References (48)

1. + pump in plasma membranes of hog stomach. J Biol Chem 251 (1976) 7690-7698
2. Hershey S.J., and Sachs G. Gastric acid secretion. Physiol Rev 75 (1995) 155-189
3. Wingo C.S., and Smolka A.J. Function and structure of H, K-ATPase in the kidney. Am J Physiol 269 (1995) F1-F16
4. Asano S., Hoshina S., Nakaie Y., Watanabe T., Sato M., Suzuki Y., et al. Functional expression of putative H, K-ATPase from guinea pig distal colon. Am J Physiol 275 (1998) C669-C674
5. +-ATPase. Am J Physiol 272 (1997) H869-H874
6. +-ATPase in vascular smooth muscle cells. Am J Physiol 262 (1992) H1955-H1958
7. + ATPase inhibitors cause relaxation of guinea pig and human airway smooth muscle in vitro. J Pharmacol Exp Ther 276 (1996) 897-903
8. Kelicen P., Pekiner C., Sarioglu Y., and Uma S. Omeprazole-induced relaxation in rat aorta is partly dependent on endothelium. Pharmacol Res 46 (2002) 321-323
9. Naseri E., and Yenisehirli A. Proton pump inhibitors omeprazole and lansoprazole induce relaxation of isolated human arteries. Eur J Pharmacol 531 (2006) 226-231
10. +-ATPase inhibitor, on rat aortic rings. Gen Pharmacol 27 (1996) 117-121
11. +-ATPase inhibitor SCH 28080. J Pharm Pharmacol 52 (2000) 857-862
12. Aydin C., Sarac B., Koyuncu A., Yildirim S., Sen M., and Sarioglu Y. Relaxant effect of omeprazole and lansoprazole in guinea pig gallbladder muscle strips in vitro. J Gastroenterol 38 (2003) 765-771
13. Crowson M.S., and Shull G.E. Isolation and characterization of a cDNA encoding the putative distal colon H,K-ATPase. Similarity of deduced amino acid sequence to gastric H,K-ATPase and Na,K-ATPase and mRNA expression in distal colon, kidney and uterus. J Biol Chem 267 (1992) 13740-13748
14. +-ATPase is selectively expressed in surface epithelial cells of rat distal colon. Am J Physiol 265 (1993) C1080-C1089
15. +ATPase in lysosomes of epithelial cells of the adult rat epididymis. Mol Reprod Dev 58 (2001) 398-410
16. Yildirim K., Sarioglu Y., Kaya T., Cetin A., and Yildirim S. Inhibitor effect of omeprazole in isolated human myometrial smooth muscle. Life Sci 69 (2001) 435-442
17. Bagcivan I., Gokce G., Ayan S., Yildirim S., Sarac B., Ki{dotless}li{dotless}carslan H., et al. Hydrogen-potassium ATPase inhibitors induce relaxation on rabbit prostatic strips in vitro. Int J Urol 9 (2002) 641-645
18. Ayan S., Sarioglu Y., Yildirim S., Gokce G., and Bagcivan I. Relaxation induced by omeprazole does not change in diabetic rabbit corpus cavernosum. BJU Int 87 (2001) 265-268
19. Sarioglu Y., Yildirim S., Utkan T., Yildirim M.K., and Uma S. Evidence of relaxant effect of omeprazole in rabbit corpus cavernosum in vitro. Life Sci 66 (2000) 1411-1421
20. Wray S. Smooth muscle intracellular pH: measurement, regulation, and function. Am J Physiol 254 (1988) C213-C225
21. Lee E.B., Cho S.I., Chang M.S., Kim K.B., Lee S.B., and Choi W.S. General pharmacological properties of YJA20379-8, a new H+/K(+)-ATPase inhibitor with anti-ulcer activities. Arzneimittelforschung 51 (2001) 659-666
22. Mulryan K., Gitterman D.P., Lewis C.J., Vial C., Leckie B.J., Brown J.E., et al. Reduced vas deferens contraction and male infertility in mice lacking P2X1 receptors. Nature 403 (2000) 86-89
23. Keeling D.J., Fallowfield C., Milliner K.J., Tingley S.K., Ife R.J., and Underwood A.H. Studies on the mechanism of action of omeprazole. Biochem Pharmacol 34 (1985) 2967-2973
24. Lindberg P., Nordberg P., Alminger T., Brandstrom A., and Wallmark B. The mechanism of action of the gastric acid secretion inhibitor omeprazole. J Med Chem 29 (1986) 1327-1329
25. +)-adenosine triphosphatase by the proton pump inhibitor AG. J Pharmacol Exp Ther 248 (1989) 799-805
26. +)-ATPase within the parietal cell. Biochim Biophys Acta 778 (1984) 549-558
27. +)-ATPase. J Biol Chem 255 (1980) 5313-5319
28. Beil W., Hackbarth I., and Swing K.F. Mechanism of gastric antisecretory effect of SCH 28080. Br J Pharmacol 88 (1986) 19-23
29. +-activated oxidizing agent of sulfydryl groups. J Biol Chem 260 (1985) 4591-4597
30. +ATPase and acid secretion by SCH 28080, a substituted pyridyl-(1,2a)imidazole. J Biol Chem 262 (1987) 2077-2084
31. Coruzzi G., Adami M., and Bertaccini G. Gastric antisecretory activity of lansoprazole indifferent experimental models: comparison with omeprazole. Gen Pharmacol 26 (1995) 1027-1032
32. Satoh H., Inatomi N., Nagaya H., Inada I., Nohara A., Nakamura N., et al. Antisecretory and antiulcer activities of a novel proton pump inhibitor AG-1749 in dogs and rats. J Pharmacol Exp Ther 248 (1989) 806-815
33. Wallmark B., Jaresten B.M., Larrsson H., Ryberg B., Brandstrom A., and Fellenius E. Differentiation among inhibitory actions of omeprazole, cimetidine, and SCN-on gastric acid secretion. Am J Physiol 245 (1983) G64-G71
34. +)-ATPase. Biochem Pharmacol 42 (1991) 123-130
35. Vesperinas G., Feddersen M., Lewin J., and Huidobro-Toro J.P. The use of ryanodine and calcium channel blockers to characterize intra- and extra-cellular calcium pools mobilized by noradrenaline in the rat vas deferens. Eur J Pharmacol 165 (1989) 309-313
36. 2+ influx in smooth muscle of rats vas deferens revealed by procaine. Br J Pharmacol 110 (1993) 1353-1358
37. Zhong H., and Minneman K.P. α1-Adrenoceptor subtypes. Eur J Pharmacol 375 (1999) 261-276
38. Yaris E., Kesim M., Kadioglu M., Kalyoncu N.I., Ulku C., and Ozyavuz R. The effects of paroxetine on rat isolated vas deferens. Pharmacol Res 48 (2003) 335-345
39. Vladimirova I., Jurkiewicz N.H., and Jurkiewicz A. Evidence for participation of nitric oxide in excitatory neurotransmitter in rat vas deferens. Life Sci 55 (1994) 1123-1128
40. Boselli S., and Govoni S. Effect of in vivo and in vitro ethanol on adrenergic and purinergic responses of the bisected rat vas deferens to low and high frequency pulses. J Auton Pharmacol 21 (2001) 171-179
41. Garces-do-Carmo L., and Santos W.S. l-NAME pre-treatment partially inhibits the agmatine-evoked depression of the electrically induced twitch contraction of isolated rat vas deferens. Life Sci 79 (2006) 854-860
42. Buyukavsar K., Levent A., and Ark M. Expression of Rho-kinase and its functional role in the contractile activity of the mouse vas deferens. Br J Pharmacol 140 (2003) 743-749
43. Cleary L., Slattery J., Bexis S., and Docherty J.R. Sympathectomy reveals alpha 1A and alpha 1D adrenoceptor components to contractions to noradrenaline in rat vas deferens. Br J Pharmacol 143 (2004) 745-752
44. Hay D.W., and Wadsworth R.M. The effects of calcium channel inhibitors on twitches and noradrenaline contractions of the rat bisected vas deferens. Eur J Pharmacol 87 (1983) 367-378
45. Burt R.P., Chapple C.R., and Marshall I. The role of diacylglycerol and activation of protein kinase C in alpha 1A-adrenoceptor-mediated contraction to noradrenaline of rat isolated epididymal vas deferens. Br J Pharmacol 117 (1996) 224-230
46. Amobi N.I.B., Sugden D., and Smith I.C.H. Characterisation of a1 adrenoceptor subtypes mediating noradrenaline-induced contraction of rat epididymal vas deferens in calcium-free medium. Life Sci 65 (1999) 187-196
47. + in rat vas deferens. Eur J Pharmacol 30 (2003) 37-43
48. Minneman K.P., Fox A.W., and Abel P.W. Occupancy of alpha-1-adrenergic receptors and contraction of rat deferens. Mol Pharmacol 23 (1983) 359-368