Frequent allelic loss at 6q26-27 in breast carcinomas of the solid-tubular histologic type

Breast Cancer

Volumn 5, Issue 2, 1998, Pages 127-130

  Bando, Koichi ^a   Matsumoto, Satoshi ^a   Onda, Masahiko ^a   Akiyama, Futoshi ^b   Sakamoto, Goi ^b   Yoshimoto, Masataka ^b   Kasumi, Fujio ^b   Nakamura, Yusuke ^c   Emi, Mitsuru ^a  

^a NIPPON MEDICAL SCHOOL   (Japan)

^b Cancer Institute Hospital   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

Author keywords

Breast cancer; Chromosome 6; Loss of heterozygosity; Ovarian cancer; Tumor suppressor gene

Indexed keywords

EID: 33845972395     PISSN: 13406868     EISSN: 18804233     Source Type: Journal    
DOI: 10.1007/BF02966684     Document Type: Article

References (12)

1. Nakamura Y: Application of DNA markers to clinical genetics. Jpn J Hum Genet 41:1-14, 1996.
2. Sato T, Saito H, Morita R, et al: Allelotype of human ovarian cancer. Cancer Res 51:5118-5122, 1991.
3. Saito S, Saito H, Koi S, et al: Fine-scale deletion mapping of the distal long arm of chromosome 6 in 70 human ovarian cancers. Cancer Res 52:5815-5817, 1992.
4. Devilee P, van Vliet M, van Sloun P, et al: Allelotype of human breast carcinoma; A second major site for loss of heterozygosity is on chromosome 6q. Oncogene 6:1705-1711, 1991. (Pubitemid 21924278)
5. Noviello C, Frank C, Charles T: Loss of heterozygosity on the long arm of chromosome 6 in breast cancer; Possibly four regions of deletion. Clin Cancer Res 2:1601-1606, 1996. (Pubitemid 126447456)
6. Emi M, Matsumoto S, Iida A: Genetic alterations in breast cancer. J Hum Genet 43, 1998. In press.
7. Iida A, Isobe R, Yoshimoto M, et al: Localization of a breast cancer tumor-suppressor gene to a 3-cM interval within chromosomal region 16q22. Br J Cancer 75:264-267, 1997. (Pubitemid 27019572)
8. Matsumoto S, Kasumi F, Sakamoto G, et al: Detailed deletion mapping of chromosome arm 3p in breast cancers; A 2-cM region on 3p14.3-21.1 and a 5-cM region on 3p24.3-25.1 commonly deleted in tumors. Genes Chrom Cancer 20:268-274, 1997. (Pubitemid 27484102)
9. Gyapay G, Morissette J, Vignal A, et al: Genethon human genetic linkage map. Nat Genet 7:246-339, 1994. (Pubitemid 2086160)
10. Chappell SA, Walsh T, Walker RA, et al: Loss of heterozygosity at chromosome 6q in preinvasive and early invasive breast carcinomas. Br J Cancer 75:1324-1329, 1997. (Pubitemid 27179823)
11. Iida A, Isobe R, Kurose K, et al: Mapping of a new target region of allelic loss to a 2-cM interval at 22ql3.1 in primary breast cancers. Genes Chrom Cancer 20:108-112, 1998. (Pubitemid 28081236)
12. Tsukamoto K, Yoshimoto M, Kasumi F, et al: Frequent multiplication of the entire long arm of chromosome 1 in primary breast cancers. Genes Chrom Cancer 21, 1998. In press.