Detailed deletion mapping of chromosome arm 3p in breast cancers: A 2- cM region on 3p14.3-21.1 and a 5-cM region on 3p24.3-25.1 commonly deleted in tumors

Genes Chromosomes and Cancer

Volumn 20, Issue 3, 1997, Pages 268-274

  Matsumoto, Satoshi ^a   Kasumi, Fujio ^b   Sakamoto, Goi ^b   Onda, Masahiko ^a   Nakamura, Yusuke ^c   Emi, Mitsuru ^a  

^a NIPPON MEDICAL SCHOOL   (Japan)

^b CANCER INSTITUTE   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; ESTROGEN RECEPTOR; PROGESTERONE RECEPTOR;

ARTICLE; BREAST CANCER; CHROMOSOME 3P; CHROMOSOME DELETION; CHROMOSOME MAP; HETEROZYGOSITY LOSS; HUMAN; HUMAN TISSUE; PRIORITY JOURNAL; TUMOR SUPPRESSOR GENE;

BREAST NEOPLASMS; CHROMOSOME DELETION; CHROMOSOME MAPPING; CHROMOSOMES, HUMAN, PAIR 3; DNA, NEOPLASM; HUMANS; LOSS OF HETEROZYGOSITY; MICROSATELLITE REPEATS; POLYMERASE CHAIN REACTION;

EID: 0030817402     PISSN: 10452257     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2264(199711)20:3<268::AID-GCC7>3.0.CO;2-0     Document Type: Article

References (31)

1. Ali IU, Lidereau R, Callahan R (1989) Presence of two members of c-erbA receptor gene family (c-erbA beta and c-erbA2) in smallest region of somatic homozygosity on chromosome 3p21-p25 in human breast carcinoma. J Natl Cancer Inst 81:1815-1820.
2. Bergthorsson JT, Eiriksdottir G, Barkardottir RB, Egilsson V, Arason A, Ingvarsson S (1995) Linkage analysis and allelic imbalance in human breast cancer kindreds using microsatellite markers from the short arm of chromosome 3. Hum Genet 96:437-143.
3. Buchhagen DL, Qiu L, Etkind P (1994) Homozygous deletion, rearrangement and hypermethylation implicate chromosome region 3p14.3-3p21.3 in sporadic breast-cancer development. Int J Cancer 57:473-479.
4. Chen LC, Kurisu W, Ljung BM, Goldman ES, Moore D 2nd, Smith HS (1992) Heterogeneity for allelic loss in human breast cancer. J Natl Cancer Inst 84:506-510.
5. Chen LC, Matsumura K, Deng G, Kurisu W, Ljung BM, Lerman MI, Waldman FM, Smith HS (1994) Deletion of two separate regions on chromosome 3p in breast cancers. Cancer Res 54:3021-5024.
6. Druck T, Kastury K, Hadaczek Piotr, Podolski J, Toloczko A, Sikorski A, Ohta M, LaForgia S, Lasota J, McCue P, Lubinski J, Huebner K (1995) Loss of heterozygosity at the familial RCC t(3;8) locus in most clear cell renal carcinomas. Cancer Res 55:5348-5353.
7. Eiriksdottir G, Bergthorsson JT, Sigurdsson H, Gudmundsson J, Skirnisdottir S, Egilsson V, Barkardottir RB, Incvarsson S (1995) Mapping of chromosome 3 alterations in human breast cancer using microsatellite PCR markers: Correlation with clinical variables. Int J Oncol 6:369-375.
8. Gemmill RM, Chumakov I, Scott P, Waggoner B, Rigault P, Cypser J, Chen Q, Weissenbach J, Gardiner K, Wang H, Pekarsky Y, Le Gall I, Le Paslier D, Guillou S, Li E, Robinson L, Hahner L, Todd S, Cohen D, Drabkin HA (1995) A second-generation YAC contig map of human chromosome 3. Nature 377:299-319.
9. Gnarra JR, Tory K, Weng Y, Schmidt L, Wei MH, Latif F, Liu S, Chen F, Duh FM, Lubensky I, Duan DR, Florence C, Pozzatti R, Walther MM, Bander NH, Grossman HB, Brauch H, Pomer S, Brooks JD, Isaacs WB, Lerman MI, Zbar B, Linehan WM (1994) Mutations of the VHL tumor suppressor gene in renal carcinoma. Nat Genet :85-90.
10. Gyapay G, Morissette J, Vignal A, Dib C, Fizames C, Millasseau P, Marc S, Bernardi G, Lathrop M, Weissenbach J (1994) Genethon human genetic linkage map. Nat Genet 7:246-539.
11. Harada Y, Katagiri T, Ito I, Akiyama F, Sakamoto G, Kasumi F, Emi M, Nakamura Y (1994) Genetic studies of 457 breast cancers: Clinicopathologic parameters compared with genetic alterations. Cancer 74:2281-2286.
12. Hibi K, Takahashi T, Yamakawa K, Ueda R, Sekido Y, Ariyoshi Y, Suyama M, Takagi H, Nakamura Y, Takahashi T (1992) Three distinct regions involved in 3p deletion in human lung cancer. Oncogene 7:445-449.
13. Ito I, Yoshimoto M, Iwase T, Watanabe S, Katagiri T, Harada Y, Kasumi F, Yasuda S, Mitomi T, Emi M, Nakamura Y (1995) Association of genetic alterations on chromosome 17 and loss of hormone receptors in breast cancer. Br J Cancer :438-441.
14. Kok K, van den Berg A, Veldhuis PM, van der Veen AY, Franke M, Schoenmakers EF, Hulsbeek MM, von der Hout AH, de Leij L, van de Ven W, Buys CH (1994) A homozygous deletion in a small cell lung cancer cell line involving a 3p21 region with a marked instability in yeast artificial chromosomes. Cancer Res 54:4183-4187.
15. Latif F, Tory K, Gnarra J, Yao M, Duh FM, Orcutt ML, Stackhouse T, Kuzmin I, Modi W, Geil L, Schmidt L, Zhou F, Li H, Wei MH, Chen F, Glenn G, Choyke P, Walther MM, Weng Y, Duan DSR, Dean M, Glavac D, Richards FM, Crossey PA, Ferguson-Smith MA, le Paslier D, Chumakov I, Cohen D, Chinault C, Maher ER, Linehan WM, Zbar B, Lerman MI (1993) Identification of the von Hippel-Lindau disease tumor suppressor gene. Science 260:1317-1320.
16. Lebeau J, Gerbault-Seureau M, Lemieux N, Apiou F, Calvo F, Berthon P, Goubin G, Dutrillaux B (1995) Loss of chromosome 3p arm differentiating tumorigenic from non-tumorigenic cells derived from the same SV40-transformed human mammary epithelial cells. Int J Cancer 60:244-248.
17. Man S, Ellis IO, Sibbering M, Blamey RW, Brook JD (1996) High levels of allele loss at the FHIT and ATM genes in non-comedo ductal carcinoma in situ and grade I tubular invasive breast cancers. Cancer Res 56:5484-5489.
18. Negrini M, Monaco C, Vorechovsky I, Ohta M, Druck T, Baffa R, Huebner K, Croce CM (1996) The FHIT gene at 3p14.2 is abnormal in breast carcinomas. Cancer Res 56:3173-3179.
19. Ohta M, Inoue H, Cotticelli MG, Kastury K, Baffa R, Palazzo J, Siprashvili Z, Mori M, McCue P, Druck T, Croce CM, Huebner K (1996) The FHIT gene, spanning the chromosome 3p14.2 fragile site and renal carcinoma-associated t(3:8) breakpoint, is abnormal in digestive tract cancers. Cell 84:587-597.
20. Panagopoulos I, Pandis N, Thelin S, Petersson C, Mertens F, Borg A, Kristoffersson U, Mitelman F, Aman P (1996) The FHIT and PTPRG genes are deleted in benign proliferative breast disease associated with familial breast cancer and cytogenetic rearrengements of chromosome band 3p14. Cancer Res 56:4871-4875.
21. Pandis N, Jin Y, Limon J, Bardi G, Idvall I, Mandahl N, Mitelman F, Heim S (1993) Interstitial deletion of the short arm of chromosome 3 as a primary chromosome abnormality in carcinomas of the breast. Genes Chromosomes Cancer 6:151-155.
22. Rimessi P, Gualandi F, Morelli C, Trabanelli C, Wu Q, Possati L, Montesi M, Barrett JC, Barbanti-Brodano G (1994) Transfer of human chromosome 3 to an ovarian carcinoma cell line identifies three regions on 3p involved in ovarian cancer. Oncogene 9:3467-3474.
23. Roz L, Wu CL, Porter S, Scully C, Speight P, Read A, Sloan P, Thakker N (1996) Allelic imbalance on chromosome 3p in oral dysplastic lesions: An early event in oral carcinogenesis. Cancer Res 56:1228-1231.
24. Saro T, Tanigami A, Yamakawa K, Akiyama F, Kasumi F, Sakamoto G, Nakamura Y (1990) Allelotype of breast cancer: Cumulative allele losses promote tumor progression in primary breast cancer. Cancer Res 50:7184-7189.
25. Sato T, Akiyama F, Sakamoto G, Kasumi F, Nakamura Y (1991) Accumulation of genetic alterations and progression of primary breast cancer. Cancer Res 51:5794-5799.
26. Sozzi G, Veronese ML, Negrini M, Baffa R, Cotticelli MG, Inoue H, Tornielli S, Pilotti S, de Gregorio L, Pastorio U, Pierotti MA, Ohta M, Huebner K, Croce CM (1996) The FHIT gene at 3p14.2 is abnormal in lung cancer. Cell 85:17-26.
27. Takita K, Sato T, Miyagi M, Watatani M, Akiyama F, Sakamoto G, Kasumi F, Abe R, Nakamura Y (1992) Correlation of loss of alleles on the short arms of chromosomes 11 and 17 with metastasis of primary breast cancer to lymph nodes. Cancer Res 52:3914-3917.
28. Teixeira MR, Pandis N, Bardi G, Andersen JA, Heim S (1996) Karyotypic comparisons of multiple tumorous and macroscopically normal surrounding tissue samples from patients with breast cancer. Cancer Res 56:855-859.
29. van den Berg A, Hulsbeek MMF, de Jong D, Kok K, Veldhuis PMJF, Roche J, Buys CHCM (1996) Major role for a 3p21 region and lack of involvement of the t(3;8) breakpoint region in the development of renal cell carcinoma suggested by loss of heterozygosity analysis. Genes Chromosomes Cancer 15:64-72.
30. Wu CL, Sloan P, Read AP, Harris R, Thakker N (1994) Deletion mapping on the short arm of chromosome 3 in squamous cell carcinoma of the oral cavity. Cancer Res 54:6484-6488
31. Yamakawa K, Takahashi T, Horio Y, Murata Y, Takahashi E, Hibi K, Yokoyama S, Ueda R, Takahashi T, Nakamura Y (1993) Frequent homozygous deletions in lung cancer cell lines detected by a DNA marker located at 3p21.3-p22. Oncogene 8:327-330.