Tomographic visualization of cholinesterase [3]

Annals of Neurology

Volumn 60, Issue 6, 2006, Pages 745-746

  Kuljis, Rodrigo O ^a   Darvesh, Sultan ^b   Greig, Nigel H ^c   Geula, Changiz ^d  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^b DALHOUSIE UNIVERSITY   (Canada)

^c NATIONAL INSTITUTE ON AGING   (United States)

^d BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 METHYL 4 PIPERIDINYL N BUTYRATE; BUTYRIC ACID DERIVATIVE; CARBON 11; CHOLINESTERASE; PIPERIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; DIAGNOSTIC VALUE; ENZYME LOCALIZATION; ENZYME SPECIFICITY; ENZYME SUBSTRATE COMPLEX; HISTOCHEMISTRY; HUMAN; IMAGE ANALYSIS; IMAGE DISPLAY; IMAGE ENHANCEMENT; LETTER; NEUROFIBRILLARY TANGLE; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; PROTEIN EXPRESSION; SYNAPSE;

ACETYLCHOLINE; ACETYLCHOLINESTERASE; ALZHEIMER DISEASE; BRAIN; BUTYRATES; BUTYRYLCHOLINESTERASE; FALSE POSITIVE REACTIONS; HUMANS; NEUROCHEMISTRY; PIPERIDINES; POSITRON-EMISSION TOMOGRAPHY; REPRODUCIBILITY OF RESULTS; SYNAPTIC TRANSMISSION;

EID: 33845970537     PISSN: 03645134     EISSN: None     Source Type: Journal    
DOI: 10.1002/ana.20926     Document Type: Letter

References (5)

1. Kuhl DE, Koeppe RA, Snyder SE, et al. In vivo butyrylcholinesterase activity is not increased in Alzheimer's disease synapses. Ann Neurol 2006;59:13-20.
2. Snyder SE, Gunpundi N, Sherman PS, et al. Radiolabeled substrates: in vitro methods for determining structure-activity relationships and identification of a positron emission tomography radiopharmaceutical for in vivo measurement of butyrylcholinesterase activity. J Cereb Blood Flow Metab 2001;21:132-143.
3. Silver A. The biology of cholinesterases. Amsterdam: Elsevier, 1974.
4. Perry EK, Perry RH, Blessed G, Tomlinson BK. Changes in brain cholinesterase in senile dementia of Alzheimer's type. Neuropathol Appl Neurobiol 1978;4:273-277.
5. Geula C, Mesulam M-M. Cholinesterases and the pathology of Alzheimer's disease. Alzheimer Dis Assoc Disord 1995;9:23-28.