Understanding iron acquisition by pathogenic leptospires: A review

Indian Journal of Medical Microbiology

Volumn 24, Issue 4, 2006, Pages 311-316

  Sritharan, M ^a   Asuthkar, S ^a   Sridhar, V ^a  

^a UNIVERSITY OF HYDERABAD   (India)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; FERRIC HYDROXAMATE UPTAKE PROTEIN COMPONENT A; HEMIN; HEMIN BINDING PROTEIN; HEMOPROTEIN; IRON; IRON BINDING PROTEIN; LACTOFERRIN; PROTEIN FECA; RECEPTOR; SIDEROPHORE; TRANSFERRIN; UNCLASSIFIED DRUG;

BACTERIAL METABOLISM; BIOAVAILABILITY; BIOCHEMISTRY; CONFERENCE PAPER; HOST; INTRACELLULAR TRANSPORT; IRON TRANSPORT; LEPTOSPIRA; MEMBRANE TRANSPORT; NONHUMAN; NUCLEOCYTOPLASMIC TRANSPORT; PROTEIN ANALYSIS;

EID: 33845940468     PISSN: 02550857     EISSN: 02550857     Source Type: Journal    
DOI: 10.4103/0255-0857.29406     Document Type: Conference Paper

References (23)

1. Chipperfield JR, Ratledge C. Salicylate is not a bacterial siderophore: A theoretical study. Biometals 2000;13:165-8.
2. Kochan I. Role of iron in the regulation of nutritional immunity. Bioorganic Chemistry 1976;2:55-7.
3. Braun V, Hantke K, Koster W. Bacterial iron transport: Mechanisms, genetics and regulation. In: Metal Ions in Biological systems. Iron transport and storage in Microorganisms, Plants and Animals. Sigel A, Sigel H, editors. Marcel Dekker: New York; 1998. p. 67-145.
4. Neilands JB. Siderophores: Structure and function of microbial iron transport compounds. J Biol Chem 1995;270:723-6.
5. Neilands JB. Effects of iron deprivation on outer membrane protein expression. Meth Enzymol 1994;235;344-52.
6. Ratledge C, Dover LG. Iron metabolism in pathogenic bacteria. Annu Rev Microbiol 2000;54:881-941.
7. Sritharan M. Iron as a candidate in virulence and pathogenesis in mycobacteria and other microorganisms. W J Microbiol Biotechnol 2000;16:769-80.
8. Genco CA, Desai PJ. Iron acquisition in the pathogenic Neisseria. Trends Microbiol 1996;4:179.
9. van der Helm D. The physiological chemistry of bacterial outer-membrane siderophore receptor proteins. In: Metal Ions in Biological systems. Iron transport and storage in Microorganisms, Plants and Animals. p. 67-145. Sigel A, Sigel H, editors. Marcel Dekker: New York; 1998. p. 355-401.
10. Koster W. ABC transporter-mediated uptake of iron, siderophores, heme and vitamin B12. Res Microbiol 2001;152:291-301.
11. Buchanan SK, Smith BS, Venkatramani L, Xia D, Esser L, Palnitkar M, et al. Crystal structure of the outer membrane active transporter FepA from Escherichia coli. Nat Struc Biol 1999;6:56-63.
12. Ferguson AD, Hofmann E, Coulton JW, Diederichs K, Welte W. Siderophore-mediated iron transport: Crystal structure of FhuA with bound lipopolysaccharide. Science 1998;282:2215-20.
13. Ferguson AD, Chakraborty R, Smith BS, Esser L, van Der Helm D, Deisenhofer J. Structural basis of gating by the outer membrane transporter FecA. Science 2002;295:1715-9.
14. Andrews SC, Robinson AK, Quinones FR. Bacterial iron homeostasis FEMS Microbiol Rev 2003;27:215-37.
15. Anderson JE, Sparling PF, Cornelissen SN. Gonococcal transferrin-binding protein-2 facilitates but is not essential for transferrin utilization. J Bacteriol 1994;176:3162-70.
16. Letoffe S, Ghigo JM, Wandersman C. Iron acquisition from heme and hemoglobin by a Serratia marcescens extracellular protein. Proc Natl Acad Sci USA 1994;91:9876-80.
17. Sritharan M, Ramadevi S, Pasupala N, Asuthkar S, Tajne S. In silico identification and modelling of a putative iron-regulated TonB-dependant outer membrane receptor protein from the genome of Leptospira interrogans serovar Lai. Online J Bioinform 2005;6:74-90.
18. Braun V, Braun M. Active transport of iron and siderophore antibiotics. Curr Opin Microbiol 2002;5:194-201.
19. Gravekamp C, van de Kemp H, Franzen M. Detection of seven species of pathogenic leptospires by PCR using two sets of primers. J Gen Microbiol 1993;139:1691-700.
20. Yuri K, Takamoto Y, Okada M, Hiramune T, Kikuchi N, Yanagawa R. Chemotaxis of leptospires to hemoglobin in relation to virulence. Infect Immun 1993;61:2270-2.
21. Lee BC. Quelling the red menace: Heme capture by bacteria. Mol Microbiol 1995;18:383-90.
22. Lee JT, Ahrenhoz DH, Nelkson RD, Simmons RL. Mechanisms of the adjuvant effect of haemoglobin in experimental peritonitis: The significance of the co-ordinated iron component. Surgery 1979;86:41-8.
23. Nascimento AL, Ko AI, Martins EA, Monteiro-Vitorello CB, et al. Comparative genomics of two Leptospira interrogans serovars reveals novel insights into physiology and pathogenesis. J Bacteriol 2004;186:2164-72.