Novel antitumor agent family of 1H-benzo[c,d]indol-2-one with flexible basic side chains: Synthesis and biological evaluation

Bioorganic and Medicinal Chemistry

Volumn 15, Issue 3, 2007, Pages 1356-1362

  Yin, Hong ^a   Xu, Yufang ^a   Qian, Xuhong ^a  

^a EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

1 (2 DIMETHYLAMINOETHYL) 1H BENZO[C,D]INDOL 2 ONE; 1 (3 DIMETHYLAMINOPROPYL) 1H BENZO[C,D]INDOL 2 ONE; 1 [2 (2 DIMETHYLAMINOETHYLAMINO)ETHYL] 1H BENZO[C,D]INDOL 2 ONE; 2 (2 CHLOROETHYL) 6 NITRO 2H ACENAPHTHYLEN 1 ONE; ANTINEOPLASTIC AGENT; DI 1H BENZO[C,D]INDOL 2 ONE ETHYLAMINE; INDOLE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CHROMATOPHORE; CONTROLLED STUDY; DNA BINDING; DRUG ACTIVITY; DRUG BINDING; DRUG DESIGN; DRUG SCREENING; DRUG SYNTHESIS; ELECTRICITY; HUMAN; HUMAN CELL; IC 50; INTERCALATION COMPLEX; LEUKEMIA P 388; MOUSE; NONHUMAN;

ANIMALS; ANTINEOPLASTIC AGENTS; DNA; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; INDOLES; INTERCALATING AGENTS; LEUKEMIA P388; LUNG NEOPLASMS; MICE; MOLECULAR STRUCTURE; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED;

EID: 33845937152     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2006.11.016     Document Type: Article

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