Synthesis, antitumor evaluation and DNA photocleaving activity of novel methylthiazonaphthalimides with aminoalkyl side chains

Bioorganic and Medicinal Chemistry Letters

Volumn 15, Issue 12, 2005, Pages 3143-3146

  Li, Zhigang ^a   Yang, Qing ^a   Qian, Xuhong ^a,b  

^a DALIAN UNIVERSITY OF TECHNOLOGY   (China)

^b EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Antitumor; Intercalate; Methylthiazonaphthalimide; Photocleaver

Indexed keywords

ALKYL GROUP; DNA; NAPHTHALENE DERIVATIVE; SUPEROXIDE;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; DNA CLEAVAGE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IC 50; MOUSE; NONHUMAN; QUANTITATIVE ANALYSIS;

ANIMALS; ANTINEOPLASTIC AGENTS; CATTLE; DNA; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; IMIDES; INHIBITORY CONCENTRATION 50; INTERCALATING AGENTS; LEUKEMIA P388; LUNG NEOPLASMS; MICE; NAPHTHALENES; RADIATION-SENSITIZING AGENTS; STRUCTURE-ACTIVITY RELATIONSHIP; SUPEROXIDES; TUMOR CELLS, CULTURED; ULTRAVIOLET RAYS;

EID: 19944413311     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2005.04.012     Document Type: Article

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