Synthesis of low-hemolytic antimicrobial dehydropeptides based on gramicidin S

Journal of Medicinal Chemistry

Volumn 49, Issue 26, 2006, Pages 7592-7595

  Yamada, Keiichi ^a   Shinoda, Shun Suke ^a   Oku, Hiroyuki ^a   Komagoe, Keiko ^b   Katsu, Takashi ^b   Katakai, Ryoichi ^a  

^a GUNMA UNIVERSITY   (Japan)

^b OKAYAMA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

(BETA 3 PYRIDYL) ALPHA,BETA DEHYDROALANINE; ALANINE DERIVATIVE; ALPHA,BETA DEHYDROPHENYLALANINE; CYCLOPEPTIDE; GRAMICIDIN S; PHENYLALANINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BETA SHEET; CIRCULAR DICHROISM; COVALENT BOND; DRUG EFFICACY; DRUG SYNTHESIS; ESCHERICHIA COLI; HEMOLYSIS; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; NUCLEAR OVERHAUSER EFFECT; PROTON NUCLEAR MAGNETIC RESONANCE; REACTION ANALYSIS; STAPHYLOCOCCUS AUREUS;

ALANINE; ANTI-BACTERIAL AGENTS; CIRCULAR DICHROISM; GRAM-POSITIVE BACTERIA; GRAMICIDIN; HEMOLYSIS; MAGNETIC RESONANCE SPECTROSCOPY; MICROBIAL SENSITIVITY TESTS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 33845936302     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm061051v     Document Type: Article

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