Effect of solvent concentration on the extraction kinetics and diffusivity of Cyclosporin A in the fungus Tolypocladium inflatum

Biotechnology and Bioengineering

Volumn 96, Issue 1, 2007, Pages 67-79

  Ly, May ^a   Margaritis, Argyrios ^a   Jajuee, Babak ^a  

^a UNIVERSITY OF WESTERN ONTARIO   (Canada)

Author keywords

Effective diffusivity of Cyclosporin A; Fungus Tolyplocadium inflatum; Immunosuppressant Cyclosporin A; Solvent extraction kinetics

Indexed keywords

ACETONE; DIFFUSION; EXTRACTION; FUNGI; LINEAR EQUATIONS; ORGANIC SOLVENTS; REACTION KINETICS; TEMPERATURE DISTRIBUTION;

EFFECTIVE DIFFUSIVITY OF CYCLOSPORIN A; FUNGUS TOLYPLOCADIUM INFLATUM; IMMUNOSUPPRESSANT CYCLOSPORIN A; SOLVENT EXTRACTION KINETICS;

DRUG PRODUCTS;

2 PROPANOL; ACETONE; CYCLOSPORIN A; IMMUNOSUPPRESSIVE AGENT; METHANOL; ORGANIC SOLVENT; SOLVENT;

AQUEOUS SOLUTION; ARTICLE; CONCENTRATION (PARAMETERS); DIFFUSION; DRUG ISOLATION; FUNGUS; KINETICS; LINEAR SYSTEM; LIQUID LIQUID EXTRACTION; MYCELIUM; NONHUMAN; NONLINEAR REGRESSION ANALYSIS; PARTITION COEFFICIENT; PHASE SEPARATION; ROOM TEMPERATURE; SOLVENT EXTRACTION; TOLYPLOCADIUM INFLATUM;

CHEMICAL FRACTIONATION; COMPUTER SIMULATION; CYCLOSPORINE; DIFFUSION; KINETICS; MITOSPORIC FUNGI; MODELS, CHEMICAL; MYCELIUM; SOLVENTS;

FUNGI; TOLYPOCLADIUM INFLATUM;

EID: 33845932667     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.21180     Document Type: Article

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