The role of Gc protein oligosaccharide structure as a risk factor for COPD

Anticancer Research

Volumn 26, Issue 6 A, 2006, Pages 4073-4078

  Ohkura, Kazuto ^a   Nagasawa, Hideko ^b   Uto, Yoshihiro ^b   Okamura, Natsuko ^b   Murakami, Aya ^b   Hori, Hitoshi ^b  

^a NAGOYA UNIVERSITY   (Japan)

^b UNIVERSITY OF TOKUSHIMA   (Japan)

Author keywords

Gc protein; Gc protein derived macrophage activating factor (GcMAF); N acetylgalactosamine

Indexed keywords

GALACTOSE; N ACETYLGALACTOSAMINE; OLIGOSACCHARIDE; VITAMIN D BINDING PROTEIN;

ALLELE; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CARBOHYDRATE ANALYSIS; CHRONIC OBSTRUCTIVE LUNG DISEASE; CONTROLLED STUDY; DIPOLE; ELECTRIC POTENTIAL; HYDROPHOBICITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN LOCALIZATION; PROTEIN STRUCTURE; RISK FACTOR; SEQUENCE HOMOLOGY; SOLVATION; X RAY CRYSTALLOGRAPHY;

ALLELES; ANIMALS; CARBOHYDRATE CONFORMATION; CARBOHYDRATE SEQUENCE; ELECTROSTATICS; GENETIC PREDISPOSITION TO DISEASE; MICE; MODELS, MOLECULAR; OLIGOSACCHARIDES; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; VITAMIN D-BINDING PROTEIN;

EID: 33845932269     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (18)

1. Fletcher C, Peto R, Tinker C and Speizer FE: The Natural History of Chronic Bronchitis: An Eight Year Follow-up Study of Working Men in London. Oxford University Press, Oxford, 1976.
2. Joos L, Pare PD and Sandford AJ: Genetic risk factors for chronic obstructive pulmonary disease. Swiss Med Wkly 132: 27-37, 2002.
3. Cooke NE and Haddad JG: Vitamin D3 binding protein (Gc-globulin). Endocr Rev 10: 294-307, 1989.
4. Yamamoto N and Homma S: Vitamin D3 binding protein (group-specific component) is a precursor for the macrophage-activating signal factor from lysophosphatidylcholine-treated lymphocytes. Proc Natl Acad Sci USA 88: 8539-8543, 1991.
5. Kew RR and Webster RO: Gc-globlin (vitamin D-binding protein) enhances the neutrophil chemotactic activity of C5a and C5a des Arg. J Clin Invest 82: 364-369, 1988.
6. Cleve H and Constans J: The mutants of the vitamin D-binding protein: more than 120 variants of the Gc/DBP system. Vox Snag 54: 215-225, 1988.
7. Yang F, Brune JL, Naylor SL, Cupples RL, Naberhaus KH and Bowman BH: Human group-specific component (Gc) is a member of the albumin family. Proc Natl Acad Sci USA 82: 7994-7998, 1985.
8. Cooke NE and David EV: Serum vitamin D-binding protein is a third member of the albumin and alpha fetoprotein gene family. J Clin Invest 76: 2420-2424, 1985.
9. Ito I, Nagai S, Hoshino Y, Muro S, Hirai T, Tsukino M and Mishitna M: Risk and severity of COPD is associated with the group-specific component of serum globulin 1F allele. Chest 125: 63-70, 2004.
10. Schellenberg D, Pare PD, Weir TD, Spinelli JJ, Walker BAM and Sandford AJ: Vitamin D binding protein variants and the risk of COPD. Am J Respir Crit Care Med 157: 957-961, 1998.
11. Svasti J, Kurosky A, Bennett A and Bowman BH: Molecular basis for the three major forms of human serum vitamin D binding protein (group specific component). Biochemistry 18: 1611-1617, 1979.
12. Yamamoto N: Structural definition of a potent macrophage activating factor derived from vitamin D3-binding protein with adjuvant activity for antibody production. Mol Immunol 33: 1157-1164, 1996.
13. Yamamoto N, Homma S and Millman I: Identification of the serum factor required for in vitro activation of macrophages. Role of vitamin D3-binding protein (group specific component, Gc) in lysophospholipid activation of mouse peritoneal macrophages. J Immunol 147: 273-280, 1991.
14. Mohamad SB, Nagasawa H, Sasaki H, Uto Y, Nakagawa Y, Kawashima K and Hori H: Gc protein-derived macrophage activating factor (GcMAF): isoelectric focusing pattern and tumoricidal activity. Anticancer Res 23: 4451-4458, 2003.
15. Ohkura K, Nagamune H and Kourai H: Structural analysis of human specific cytolysin intermedilysin aiming application to cancer immunotherapy. Anticancer Res 24: 3343-3354, 2004.
16. Ohkura K, Sukeno A, Nagamune H and Kourai H: Bridge-linked bis-quaternary ammonium antimicrobial agents: relationship between cytotoxicity and antibacterial activity of 5,5′-[2,2′-(tetramethylenedicarbonyldioxy) diethyl]bis(3-alkyl-4 methyl-thiazonium iodide)s. Bioorg Med Chem 13: 2579-2587, 2005.
17. Li SC, Mazzotta MY, Chien SF and Li YT: Isolation and characterization of jack bean beta-galactosidase. J Biol Chem 250: 6786-6791, 1975.
18. Distler JJ and Jourdan GW: The purification and properties of beta-galactosidase from bovine testes. J Biol Chem 248: 6772-6780, 1973.