Role of the RIC-3 protein in trafficking of serotonin and nicotinic acetylcholine receptors

Journal of Molecular Neuroscience

Volumn 30, Issue 1-2, 2006, Pages 153-156

  Castillo, Mar ^a   Mulet, José ^a   Gutiérrez, Luis M ^a   Ortiz, José A ^a   Castelán, Francisco ^a   Gerber, Susana ^a   Sala, Salvador ^a   Sala, Francisco ^a   Criado, Manuel ^a  

^a INSTITUTO DE NEUROCIENCIAS   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA4 BETA2 NICOTINIC ACETYLCHOLINE RECEPTOR; BETA2 NICOTINIC ACETYLCHOLINE RECEPTOR; BUNGAROTOXIN RECEPTOR; ISOPROTEIN; NICOTINIC RECEPTOR; PROTEIN RIC 3; RECEPTOR SUBUNIT; SEROTONIN 3 RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; CARBOXY TERMINAL SEQUENCE; CELL MEMBRANE; CONFERENCE PAPER; CONTROLLED STUDY; FUNCTIONAL PROTEOMICS; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN TRANSPORT; RECEPTOR INTRINSIC ACTIVITY;

ANIMALS; CERCOPITHECUS AETHIOPS; COS CELLS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; RECEPTORS, NICOTINIC; RECEPTORS, SEROTONIN; RECOMBINANT PROTEINS; TRANSFECTION;

EID: 33845924681     PISSN: 08958696     EISSN: None     Source Type: Journal    
DOI: 10.1385/JMN:30:1:153     Document Type: Conference Paper

References (12)

1. Eisele J. L., Bertrand S., Galzi J. L., Devillers-Thiery A., Changeux J.- P., and Bertrand D. (1993) Chimaeric nicotinic-serotonergic receptor combines distinct ligand binding and channel specificities. Nature 366, 479-483.
2. García-Guzmán M., Sala F., Sala S., Campos-Caro A., and Criado M. (1994) Role of two acetylcholine receptor subunit domains in homomer formation and intersubunit recognition, as revealed by alpha 3 and alpha 7 subunit chimeras. Biochemistry 33, 15,198-15,203.
3. Halevi S., McKay J., Palfreyman M., Yassin L., Margalit E., Jorgensen E., and Treinin M. (2002) The C. elegans ric-3 gene is required for maturation of nicotinic acetylcholine receptors. EMBO J. 21, 1012-1020.
4. Halevi S., Yassin L., Eshel M., Sala F., Sala S., Criado M., and Treinin M. (2003) Conservation within the RIC-3 gene family. Effectors of mammalian nicotinic acetylcholine receptor expression. J. Biol. Chem. 278, 34,411-34,417.
5. Keller S. H. and Taylor P. (1999) Determinants responsible for assembly of the nicotinic acetylcholine receptor. J. Gen. Physiol. 113, 171-176.
6. Kittler J. T. and Moss S. J. (2003) Modulation of GABAA receptor activity by phosphorylation and receptor trafficking: implications for the efficacy of synaptic inhibition. Curr. Opin. Neurobiol. 13, 341-347.
7. Kneussel M. and Betz H. (2000) Clustering of inhibitory neurotransmitter receptors at developing postsynaptic sites: the membrane activation model. Trends Neurosci. 23, 429-435.
8. Margeta-Mitrovic M., Jan Y. N., and Jan L.Y. (2000) A trafficking checkpoint controls GABA(B) receptor heterodimerization. Neuron 27, 97-106.
9. Millar N. S. (2003) Assembly and subunit diversity of nicotinic acetylcholine receptors. Biochem. Soc. Trans. 31, 869-874.
10. Valor L. M., Mulet J., Sala F., Sala S., Ballesta J. J., and Criado M. (2002) Role of the large cytoplasmic loop of the alpha 7 neuronal nicotinic acetylcholine receptor subunit in receptor expression and funtion. Biochemistry 41, 7931-7938.
11. Wanamaker C. P., Christianson J. C., and Green W. M. (2003) Regulation of nicotinic acetylcholine receptor assembly. Ann. N. Y. Acad. Sci. 998, 66-80.
12. Zerangue N., Schwappach B., Jan Y. N., and Jan L. Y. (1999) Anew ER trafficking signal regulates the subunit stoichiometry of plasma membrane K (ATP) channels. Neuron 22, 537-548.