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Volumn 26, Issue 6 A, 2006, Pages 4055-4062

Molecular dynamics of human-specific cytolysin: Analysis of membrane binding motif for therapeutic application

Author keywords

Cholesterol; Cytolysin; Intermedilysin

Indexed keywords

CHOLESTEROL; CYTOLYSIN; INTERMEDILYSIN; MUTANT PROTEIN; STREPTOLYSIN O; UNCLASSIFIED DRUG;

EID: 33845923346     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (15)

References (11)
  • 2
    • 6344221692 scopus 로고    scopus 로고
    • Structural analysis of human specific cytolysin intermedilysin aiming application to cancer immunotherapy
    • Ohkura K, Nagamune H and Kourai H: Structural analysis of human specific cytolysin intermedilysin aiming application to cancer immunotherapy. Anticancer Res 24: 3343-3354, 2004.
    • (2004) Anticancer Res , vol.24 , pp. 3343-3354
    • Ohkura, K.1    Nagamune, H.2    Kourai, H.3
  • 3
    • 0033986813 scopus 로고    scopus 로고
    • Thiol-activated cytolysins: Structure, function and role in pathogenesis
    • Billington SJ, Jost BH and Songer JG: Thiol-activated cytolysins: structure, function and role in pathogenesis. FEMS Microbiol Lett 182: 197-205, 2000.
    • (2000) FEMS Microbiol Lett , vol.182 , pp. 197-205
    • Billington, S.J.1    Jost, B.H.2    Songer, J.G.3
  • 4
    • 0027526035 scopus 로고
    • The projection structure of perfringolysin-O (Clostridium perfringens thetatoxin)
    • Olofsson A, Herbert H and Thelestam M: The projection structure of perfringolysin-O (Clostridium perfringens thetatoxin). FEBS Lett 379: 125-127, 1993.
    • (1993) FEBS Lett , vol.379 , pp. 125-127
    • Olofsson, A.1    Herbert, H.2    Thelestam, M.3
  • 5
    • 0032007852 scopus 로고    scopus 로고
    • A conserved tryptophan in pneumolysin is a determinant of the characteristics of channels formed by pneumolysin in cells and planar lipid bilayers
    • Korchev YE, Bashford CL, Pederzolli C, Pasternak CA, Morgan PJ, Andrew PW and Mitchell TJ: A conserved tryptophan in pneumolysin is a determinant of the characteristics of channels formed by pneumolysin in cells and planar lipid bilayers. Biochem J 329: 571-577, 1998.
    • (1998) Biochem J , vol.329 , pp. 571-577
    • Korchev, Y.E.1    Bashford, C.L.2    Pederzolli, C.3    Pasternak, C.A.4    Morgan, P.J.5    Andrew, P.W.6    Mitchell, T.J.7
  • 6
    • 0029972377 scopus 로고    scopus 로고
    • Contribution of individual tryptophan residues to the structure and activity of θ-toxin (perfringolysin O), a cholesterol-binding cytolysin
    • Sekino-Suzuki N, Nakamura M, Mitsui K and O-Iwashita Y: Contribution of individual tryptophan residues to the structure and activity of θ-toxin (perfringolysin O), a cholesterol-binding cytolysin. Eur J Biochem 241: 941-947, 1996.
    • (1996) Eur J Biochem , vol.241 , pp. 941-947
    • Sekino-Suzuki, N.1    Nakamura, M.2    Mitsui, K.3    O-Iwashita, Y.4
  • 7
    • 0029810794 scopus 로고    scopus 로고
    • Conversion of an extracellular cytolysin into a phagosome-specific lysin which supports the growth of an intracellular pathogen
    • Jones S, Preiter K and Portnoy D: Conversion of an extracellular cytolysin into a phagosome-specific lysin which supports the growth of an intracellular pathogen. Mol Microbiol 21: 1219-1225, 1996.
    • (1996) Mol Microbiol , vol.21 , pp. 1219-1225
    • Jones, S.1    Preiter, K.2    Portnoy, D.3
  • 8
    • 0030037295 scopus 로고    scopus 로고
    • Intermedilysin, a novel cytotoxin specific for human cells, secreted by Streptococcus intermedius UNS46 isolated from a human liver abscess
    • Nagamune H, Ohnishi C, Katsuura A, Fushitani K, Whiley RA, Tsuji A and Matsuda Y: Intermedilysin, a novel cytotoxin specific for human cells, secreted by Streptococcus intermedius UNS46 isolated from a human liver abscess. Infect Immun 64: 3093-3100, 1996.
    • (1996) Infect Immun , vol.64 , pp. 3093-3100
    • Nagamune, H.1    Ohnishi, C.2    Katsuura, A.3    Fushitani, K.4    Whiley, R.A.5    Tsuji, A.6    Matsuda, Y.7
  • 9
    • 0032977367 scopus 로고    scopus 로고
    • Analysis of structure-permeability correlation of nitrophenol analogues in newborn rat abdominal skin using semiempirical molecular orbital calculation
    • Ohkura K and Hori H: Analysis of structure-permeability correlation of nitrophenol analogues in newborn rat abdominal skin using semiempirical molecular orbital calculation. Bioorg Med Chem 7: 309-314, 1999.
    • (1999) Bioorg Med Chem , vol.7 , pp. 309-314
    • Ohkura, K.1    Hori, H.2
  • 10
    • 0242361210 scopus 로고    scopus 로고
    • Analysis of structural features of bis-quaternary ammonium antimicrobial agents 4,4′-(α,ω-Polymethylenedithio) bis(1-alkylpyridinium iodide)s using computational simulation
    • Ohkura K, Sukeno A, Yamamoto K, Nagamune H, Maeda T and Kourai H: Analysis of structural features of bis-quaternary ammonium antimicrobial agents 4,4′-(α,ω-Polymethylenedithio) bis(1-alkylpyridinium iodide)s using computational simulation. Bioorg Med Chem 11: 5035-5043, 2003.
    • (2003) Bioorg Med Chem , vol.11 , pp. 5035-5043
    • Ohkura, K.1    Sukeno, A.2    Yamamoto, K.3    Nagamune, H.4    Maeda, T.5    Kourai, H.6
  • 11
    • 4444317357 scopus 로고    scopus 로고
    • Angiogenesis inhibitor TX-1898: Syntheses of the enantiomers of sterically diverse haloacetylcarbamoyl-2-nitroimidazole hypoxic cell radiosensitizers
    • Jin CZ, Nagasawa H, Shimamura M, Uto Y, Inayama S, Takeuchi Y, Kirk KL and Hori H: Angiogenesis inhibitor TX-1898: syntheses of the enantiomers of sterically diverse haloacetylcarbamoyl-2-nitroimidazole hypoxic cell radiosensitizers. Bioorg Med Chem 12: 4917-4927, 2004.
    • (2004) Bioorg Med Chem , vol.12 , pp. 4917-4927
    • Jin, C.Z.1    Nagasawa, H.2    Shimamura, M.3    Uto, Y.4    Inayama, S.5    Takeuchi, Y.6    Kirk, K.L.7    Hori, H.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.