Synthesis of murisolin, (15R, 16R, 19R, 20S)-murisolin A, and (15R, 16R, 19S, 20S)-16,19-cis-murisolin and their inhibitory action with bovine heart mitochondrial complex I

Chemistry - An Asian Journal

Volumn 1, Issue 6, 2006, Pages 894-904

  Hattori, Yasunao ^a   Kimura, Yuka ^a   Moroda, Aki ^a   Konno, Hiroyuki ^b   Abe, Masato ^c   Miyoshi, Hideto ^c   Goto, Tetsuhisa ^a   Makabe, Hidefumi ^a  

^a SHINSHU UNIVERSITY   (Japan)

^b KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

^c KYOTO UNIVERSITY   (Japan)

Author keywords

Annonaceous acetogenins; Antitumor agents; Mitochondrial complex I; Natural products; Total synthesis

Indexed keywords

ENZYME INHIBITOR; FURAN DERIVATIVE; LACTONE; MURISOLIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); UNCLASSIFIED DRUG;

ANIMAL; ARTICLE; CATTLE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; HEART MITOCHONDRION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; STEREOISOMERISM; SYNTHESIS;

ANIMALS; CATTLE; ELECTRON TRANSPORT COMPLEX I; ENZYME INHIBITORS; FURANS; LACTONES; MAGNETIC RESONANCE SPECTROSCOPY; MITOCHONDRIA, HEART; MOLECULAR STRUCTURE; STEREOISOMERISM;

EID: 33845922401     PISSN: 18614728     EISSN: 1861471X     Source Type: Journal    
DOI: 10.1002/asia.200600261     Document Type: Article

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