Total synthesis and structure confirmation of the annonaceous acetogenins 30(S)-hydroxybullatacin, uvarigrandin A, and 5(R)-uvarigrandin a (narumicin I?)

Journal of Organic Chemistry

Volumn 68, Issue 5, 2003, Pages 1780-1785

  Marshall, James A ^a   Piettre, Arnaud ^a   Paige, Mikell A ^a   Valeriote, Frederick ^b  

^a UNIVERSITY OF VIRGINIA   (United States)

^b Josephine Ford Cancer Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ESTERS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; STRUCTURE (COMPOSITION); SYNTHESIS (CHEMICAL);

CORE SEGMENTS;

ORGANIC COMPOUNDS;

5 HYDROXYBULLATACIN; ACETOGENIN; BULLATACIN; BUTENOLIDE; ESTER DERIVATIVE; FLUOROURACIL; HYDROXYL GROUP; MALIC ACID; NARUMICIN I; PLANT EXTRACT; TETRAHYDROFURAN DERIVATIVE; UNCLASSIFIED DRUG; UVARIGRANDIN A;

ANNONA BULLATA; ANTINEOPLASTIC ACTIVITY; ARTICLE; BARK; CHEMICAL REACTION; CHIRALITY; CONTROLLED STUDY; DRUG ISOLATION; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROTON NUCLEAR MAGNETIC RESONANCE; STEREOCHEMISTRY; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; TECHNIQUE;

4-BUTYROLACTONE; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CATALYSIS; COLONIC NEOPLASMS; DRUG SCREENING ASSAYS, ANTITUMOR; FURANS; HUMANS; INDICATORS AND REAGENTS; LACTONES; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR STRUCTURE; STEREOISOMERISM; TUMOR CELLS, CULTURED;

EID: 0037424443     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo0266137     Document Type: Article

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