Synthesis and antitumor activity of guanylhydrazones from 6-(2,4-dichloro-5-nitrophenyl)imidazo[2,1-b]thiazoles and 6-pyridylimidazo[2,1- b]thiazoles

Journal of Medicinal Chemistry

Volumn 49, Issue 26, 2006, Pages 7897-7901

  Andreani, Aldo ^a   Burnelli, Silvia ^a   Granaiola, Massimiliano ^a   Leoni, Alberto ^a   Locatelli, Alessandra ^a   Morigi, Rita ^a   Rambaldi, Mirella ^a   Varoli, Lucilla ^a   Farruggia, Giovanna ^a   Stefanelli, Claudio ^a   Masotti, Lanfranco ^a   Kunkel, Mark W ^b  

^a UNIVERSITY OF BOLOGNA   (Italy)

^b NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSYLMETHIONINE DECARBOXYLASE; AMIDINOHYDRAZONE; IMIDAZO[2,1 B]BENZOTHIAZOLE DERIVATIVE;

ALGORITHM; ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL CYCLE; CELL STRAIN HL 60; CHEMICAL REACTION; CONTROLLED STUDY; DRUG DESIGN; DRUG EFFECT; DRUG MECHANISM; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVITY; HEALTH CARE ORGANIZATION; HUMAN; HUMAN CELL; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE;

ADENOSYLMETHIONINE DECARBOXYLASE; ANTINEOPLASTIC AGENTS; CELL CYCLE; CELL DEATH; DRUG SCREENING ASSAYS, ANTITUMOR; HL-60 CELLS; HUMANS; HYDRAZONES; MEMBRANE POTENTIAL, MITOCHONDRIAL; MOLECULAR STRUCTURE; NEOPLASMS; STRUCTURE-ACTIVITY RELATIONSHIP; THIAZOLES; TUMOR CELLS, CULTURED;

EID: 33845917814     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm061077m     Document Type: Article

References (21)

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