Dietary lipids and the brain during development and ageing

Scandinavian Journal of Food and Nutrition

Volumn 50, Issue SUPPL. 2, 2006, Pages 27-32

  Uauy, Ricardo ^a,b   Dangour, Alan ^b  

^a UNIVERSITY OF CHILE   (Chile)

^b LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

Author keywords

Ageing; Brain; Development; Docosahexaenoic acid; n 3 fatty acids; Retina

Indexed keywords

ARACHIDONIC ACID; DOCOSAHEXAENOIC ACID; ICOSANOID; ICOSAPENTAENOIC ACID; LINOLEIC ACID; LONG CHAIN FATTY ACID; NEUROTROPHIC FACTOR; OMEGA 3 FATTY ACID; OMEGA 6 FATTY ACID; POLYUNSATURATED FATTY ACID; TRIACYLGLYCEROL;

AGING; BRAIN CORTEX; BRAIN DEVELOPMENT; BREAST MILK; CHOLESTEROL SYNTHESIS; COGNITIVE DEFECT; CONFERENCE PAPER; DEMENTIA; HUMAN; INFLAMMATION; LIPID DIET; NONHUMAN; PHOTOSTIMULATION; PREMATURITY; RETINA DEVELOPMENT; THROMBOCYTE AGGREGATION; VASODILATATION; VISUAL ACUITY;

EID: 33845899387     PISSN: 17482976     EISSN: 17482984     Source Type: Journal    
DOI: 10.1080/17482970601066439     Document Type: Conference Paper

References (26)

1. Uauy R, Hoffman DR, Peirano P, Birch DG, Birch EE. Essential fatty acids in visual and brain development. Lipids 2001; 36: 885-95.
2. Uauy R, Dangour AD. Nutrition in brain development and ageing: the role of essential fatty acids. Nutr Rev 2006; 64: S24-33.
3. Litman BJ, Mitchell DC. A role for phospholipid polyunsaturation in modulating membrane protein function. Lipids 1996; 31: S193-7.
4. Calder PC. n-3 Polyunsaturated fatty acids, inflammation, and inflammatory diseases. Am J Clin Nutr 2006; 83: S1505-19.
5. Oppenheim RW. Cell death during development of the nervous system. Annu Rev Neurosci 1991; 14: 453-501.
6. Rotstein N, Aveldaño MI, Barrantes FJ, Roccamo AM, Politi LE. Apoptosis of retinal photoreceptors during development in vitro: protective effect of docosahexaenoic acid. J Neurochem 1997; 69: 504-13.
7. Rotstein N, Aveldaño MI, Barrantes FJ, Politi LE. Docosahexaenoic acid is required for the survival of rat retinal photoreceptors in vitro. J Neurochem 1996; 66: 1851-9.
8. Kishida E, Yano M, Kasahara M, Masuzawa Y. Distinctive inhibitory activity of docosahexaenoic acid against sphingosine-induced apoptosis. Biochim Biophys Acta 1998; 1391: 401-8.
9. Kim H-Y, Akbar M, Lau A, Edsall L. Inhibition of neuronal apoptosis by docosahexanoic acid (22:6n-3). J Biol Chem 2000; 275: 35215-23.
10. Galli C, Trzeciak HI, Paoletti R. Effects of dietary fatty acids on the fatty acid composition of brain ethanolamine phosphoglyceride: reciprocal replacement of n-6 and n-3 polyunsaturated fatty acids. Biochim Biophys Acta 1971; 248: 449-54.
11. Greiner RC,Winter J, Nathanielsz PW, Brenna JT. Brain docosahexaenoate accretion in fetal baboons: bioequivalence of dietary alpha-linolenic and docosahexaenoic acids. Pediatr Res 1997; 42: 826-34.
12. Llanos A, Li Y, Mena P, Salem N Jr, Uauy R. Infants with intrauterine growth restriction have impaired formation of docosahexaenoic acid in early neonatal life: a stable isotope study. Pediatr Res 2005; 58: 735-40.
13. Soderberg M, Edlund C, Kristensson K, Dallner G. Lipid compositions of different regions of the human brain during aging. J Neurochem 1990; 54: 415-23.
14. Suzuki H, Park SJ, Tamura M, Ando S. Effect of the long-term feeding of dietary lipids on the learning ability, fatty acid composition of brain stem phospholipids and synaptic membrane fluidity in adult mice: a comparison of sardine oil diet with palm oil diet. Mech Aging Dev 1998; 101: 119-28.
15. Kalmijn S, van Boxtel MP, Ocke M, Verschuren WM, Kromhout D, Launer LJ. Dietary intake of fatty acids and fish in relation to cognitive performance at middle age. Neurology 2004; 62: 275-80.
16. Kalmijn S, Feskens EJ, Launer LJ, Kromhout D. Polyunsaturated fatty acids, antioxidants, and cognitive function in very old men. Am J Epidemiol 1997; 145: 33-41.
17. Barberger-Gateau P, Letenneur L, Deschamps V, Peres K, Dartigues JF, Renaud S. Fish, meat, and risk of dementia: cohort study. BMJ 2002; 325: 932-3.
18. Uauy R, Valenzuela A. Marine oils: the health benefits of n-3 fatty acids. Nutrition 2000; 16: 680-4.
19. O'Brien JT, Erkinjuntti T, Reisberg B, Roman G, Sawada T, Pantoni L, et al. Vascular cognitive impairment. Lancet Neurology 2003; 2: 89-98.
20. Vermeer SE, Prins ND, den Heijer T, Hofman A, Koudstaal PJ, Breteler MM. Silent brain infarcts and the risk of dementia and cognitive decline. N Engl J Med 2003; 348: 1215-22.
21. Marcheselli VL, Hong S, Lukiw WJ, Tian XH, Gronert K, Musto A, et al. Novel docosanoids inhibit brain ischemia-reperfusion-mediated leukocyte infiltration and pro-inflammatory gene expression. J Biol Chem 2003; 278: 43807-17.
22. Mukherjee PK, Marcheselli VL, Serhan CN, Bazan NG. Neuroprotectin D1: a docosahexaenoic acid derived docosatriene protects human retinal pigment epithelial cells from oxidative stress. Proc Natl Acad Sci USA 2004; 101: 8491-6.
23. Rojas CV, Martinez JI, Flores I, Hoffman DR, Uauy R. Gene expression analysis in human fetal retinal explants treated with docosahexaenoic acid. Invest Ophthalmol Vis Sci 2003; 44: 3170-7.
24. Calon F, Lim GP, Yang F, Morihara T, Teter B, Ubeda O, et al. Docosahexaenoic acid protects from dendritic pathology in an Alzheimer's disease mouse model. Neuron 2004; 43: 633-45.
25. Lim WS, Gammack JK, Van Niekerk J, Dangour AD. Omega 3 fatty acid for the prevention of dementia. Cochrane Database Syst Rev 2006; Issue 1. Article No. CD005379.pub2. DOI:10.1002/14651858.CD0053 79.pub2.
26. Dangour AD, Clemens F, Elbourne D, Fasey N, Fletcher AE, Hardy P, et al. A randomised controlled trial investigating the effect of n-3 long-chain polyunsaturated fatty acid supplementation on cognitive and retinal function in cognitively healthy older people: the Older People And n-3 Long-chain polyunsaturated fatty acids (OPAL) study protocol [ISRCTN72331636]. Nutrition Journal 2006; 5: 20.