Cyclooxygenase, p38 mitogen-activated protein kinase (MAPK), extracellular signal-regulated kinase MAPK, Rho kinase, and Src mediate hydrogen peroxide-induced contraction of rat thoracic aorta and vena cava

Journal of Pharmacology and Experimental Therapeutics

Volumn 320, Issue 1, 2007, Pages 236-243

  Thakali, Keshari ^a   Davenport, Lauren ^a   Fink, Gregory D ^a   Watts, Stephanie W ^a  

^a MICHIGAN STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

15 HYDROXY 11ALPHA,9ALPHA EPOXYMETHANOPROSTA 5,13 DIENOIC ACID; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 MORPHOLINO 8 PHENYLCHROMONE; 4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; 4 AMINO 7 TERT BUTYL 5 (4 METHYLPHENYL)PYRAZOLO[3,4 D]PYRIMIDINE; 7 [4 (2 HYDROXYPHENYL) 2 TRIFLUOROMETHYL 1,3 DIOXAN 5 YL] 5 HEPTENOIC ACID; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; HYDROGEN PEROXIDE; INDOMETACIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN TYROSINE KINASE; RHO KINASE; THROMBOXANE B2;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTERY CONSTRICTION; ARTICLE; BLOOD VESSEL TONE; CAVA VEIN; CONTROLLED STUDY; DRUG MECHANISM; ENZYME INHIBITION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SMOOTH MUSCLE CONTRACTION; THORACIC AORTA; VENOCONSTRICTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; AORTA, THORACIC; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HYDROGEN PEROXIDE; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; PROTEIN-SERINE-THREONINE KINASES; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES; THROMBOXANE A2; VASOCONSTRICTION; VENAE CAVAE;

EID: 33845892562     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.106.110650     Document Type: Article

References (36)

1. Ardanaz N and Pagano PJ (2006) Hydrogen peroxide as a paracrine vascular mediator: regulation and signaling leading to dysfunction. Exp Biol Med 231:237-251.
2. Banes A, Florian JA, and Watts SW (1999) Mechanisms of 5-hydroxytryptamine(2A) receptor activation of the mitogen-activated protein kinase pathway in vascular smooth muscle. J Pharmacol Exp Ther 291:1179-1187.
3. Bos CL, Richel DJ, Ritsema T, Peppelenbosch MP, and Versteeg HH (2004) Prostanoids and prostanoid receptors in signal transduction. Int J Biochem Cell Biol 36:1187-1205.
4. Cai H (2005) NAD(P)H oxidase-dependent self-propagation of hydrogen peroxide and vascular disease. Circ Res 96:818-822.
5. Chandra TS, Nath N, Suzuki H, and Seidel JC (1985) Modification of thiols of gizzard myosin alters ATPase activity, stability of myosin filaments, and the 6-10 S conformational transition. J Biol Chem 260:202-207.
6. Davidge ST (2001) Prostaglandin H synthase and vascular function. Circ Res 89:650-660.
7. Davies SP, Reddy H, Caivano M, and Cohen P (2000) Specificity and mechanism of action of some commonly used protein kinase inhibitors. Biochem J 351:95-105.
8. Florian JA and Watts SW (1999) Epidermal growth factor: a potent vasoconstrictor in experimental hypertension. Am J Physiol 276:H976-H983.
9. Gao YJ and Lee RM (2001) Hydrogen peroxide induces a greater contraction in mesenteric arteries of spontaneously hypertensive rats through thromboxane A(2) production. Br J Pharmacol 134:1639-1646.
10. Griendling KK, Sorescu D, Lassegue B, and Ushio-Fukai M (2000) Modulation of protein kinase activity and gene expression by reactive oxygen species and their role in vascular physiology and pathophysiology. Arterioscler Thromb Vasc Biol 20:2175-2183.
11. Guyton AV (1955) Determination of cardiac output by equating venous return curves with cardiac response curves. Physiol Rev 35:123-129.
12. 2-induced contraction in pulmonary artery. Am J Physiol 272:H2686-H2692.
13. Johnson RJ, Galligan JJ, and Fink GD (2001) Factors affecting endothelin-induced venous tone in conscious rats. J Cardiovasc Pharmacol 37:187-195.
14. Kalgutkar AS, Marnett AB, Crews BC, Remmel RP, and Marnett LJ (2000) Ester and amide derivatives of the nonsteroidal antiinflammatory drug, indomethacin, as selective cyclooxygenase-2 inhibitors. J Med Chem 43:2860-2870.
15. Kulmacz RJ (2005) Regulation of cyclooxygenase catalysis by hydroperoxides. Biochem Biophys Res Commun 338:25-33.
16. Lassegue B and Griendling KK (2004) Reactive oxygen species in hypertension: an update. Am J Hypertens 17:852-860.
17. Lucchesi PA, Belmadani S, and Matrougui K (2005) Hydrogen peroxide acts as both vasodilator and vasoconstrictor in the control of perfused mouse mesenteric resistance arteries. J Hypertens 23:571-579.
18. Martin DS, Rodrigo MC, and Appelt CW (1998) Venous tone in the developmental stages of spontaneous hypertension. Hypertension 31:139-144.
19. Ngai PK and Walsh MP (1987) Purification of smooth-muscle myosin free of calmodulin and myosin light-chain kinase: susceptibility to oxidation. Biochem J 246:205-211.
20. Northcott CA, Poy MN, Najjar SM, and Watts SW (2002) Phosphoinositide 3-kinase mediates enhanced spontaneous and agonist-induced contraction in aorta of deoxycorticosterone acetate-salt hypertensive rats. Circ Res 91:360-369.
21. Oeckler RA, Arcuino E, Ahmad M, Olson SC, and Wolin MS (2005) Cytosolic NADH redox and thiol oxidation regulate pulmonary arterial force through ERK MAP kinase. Am J Physiol 288:L1017-L1025.
22. 20 phosphorylation-independent contraction in intact and permeabilized vascular muscle. Am J Physiol 279:H1185-H1193.
23. 2-induced arterial muscle contraction. Am J Physiol 279:H1194-H1200.
24. Rhee SG, Bae YS, Lee SR, and Kwon J (2000) Hydrogen peroxide: a key messenger that modulates protein phosphorylation through cysteine oxidation. Sci STKE 53:PE1.
25. Rhee SG, Kang SW, Jeong W, Chang TS, Yang KS, and Woo HA (2005) Intracellular messenger function of hydrogen peroxide and its regulation by peroxiredoxins. Curr Opin Cell Biol 17:183-189.
26. Rodriguez-Martinez MA, Garcia-Cohen EC, Baena AB, Gonzalez R, Salaices M, and Marin J (1998) Contractile responses elicited by hydrogen peroxide in aorta from normotensive and hypertensive rats. Endothelial modulation and mechanism involved. Br J Pharmacol 125:1329-1335.
27. + channels. Am J Physiol 291:H2473-H2482.
28. 2-induced contractions of pulmonary arteries. Am J Physiol 264:H1542-H1547.
29. Smith WL, DeWitt DL, and Garavito RM (2000) Cyclooxygenases: structural, cellular, and molecular biology. Annu Rev Biochem 69:145-182.
30. Sparrow MP, Maxwell LC, Ruegg JC, and Bohr DF (1970) Preparation and properties of a calcium ion-sensitive actomyosin from arteries. Am J Physiol 219:1366-1372.
31. Tazzeo T, Miller J, and Janssen LJ (2003) Vasoconstrictor responses, and underlying mechanisms, to isoprostanes in human and porcine bronchial arterial smooth muscle. Br J Pharmacol 140:759-763.
32. Thakali K, Demel SL, Fink GD, and Watts SW (2005) Endothelin-1-induced contraction in veins is independent of hydrogen peroxide. Am J Physiol 289:H1115-H1122.
33. Thakali K, Davenport L, Fink GD, and Watts SW (2006) Pleiotropic effects of hydrogen peroxide in arteries and veins from normotensive and hypertensive rats. Hypertension 47:482-487.
34. Watts SW (1996) Serotonin activates the mitogen-activated protein kinase pathway in vascular smooth muscle: use of the mitogen-activated protein kinase kinase inhibitor PD098059. J Pharmacol Exp Ther 279:1541-1550.
35. Wolin MS, Gupte SA, and Oeckler RA (2002) Superoxide in the vascular system. J Vasc Res 39:191-207.
36. Yang ZW, Zheng T, Zhang A, Altura BT, and Altura BM (1998) Mechanisms of hydrogen peroxide-induced contraction of rat aorta. Eur J Pharmacol 344:169-181.