Synthesis and pharmacological evaluation of some dual-acting amino-alcohol ester derivatives of flurbiprofen and 2-[1,1′-biphenyl-4-yl]acetic acid: A potential approach to reduce local gastrointestinal toxicity

Chemistry and Biodiversity

Volumn 3, Issue 11, 2006, Pages 1238-1248

  Kumar Halen, Parmeshwari Kuldeep ^a   Chagti, Kewal Krishna ^a   Giridhar, Rajani ^a   Yadav, Mange Ram ^a  

^a M S UNIVERSITY OF BARODA   (India)

Author keywords

[No Author keywords available]

Indexed keywords

2 (DIETHYLAMINO)ETHYL 2 (2 FLUORO[1,1' BIPHENYL 4 YL])PROPANOATE; 2 (DIETHYLAMINO)ETHYL[1,1' BIPHENYL] 4 ACETATE; 2 (DIMETHYLAMINO)ETHYL 2 (2 FLUORO[1,1' BIPHENYL 4 YL])PROPANOATE; 2 (DIMETHYLAMINO)ETHYL[1,1' BIPHENYL] 4 ACETATE; 2 (MORPHOLIN 4 YL)ETHYL 2 (2 FLUORO[1,1' BIPHENYL 4 YL])PROPANOATE; 2 (MORPHOLIN 4 YL)ETHYL[1,1' BIPHENYL] 4 ACETATE; 2 (PIPERIDIN 1 YL)ETHYL 2 (2 FLUORO[1,1' BIPHENYL 4 YL])PROPANOATE; 2 (PIPERIDIN 1 YL)ETHYL[1,1' BIPHENYL] 4 ACETATE; 2 (PYRROLIDIN 1 YL)ETHYL 2 (2 FLUORO[1,1' BIPHENYL 4 YL])PROPANOATE; 2 (PYRROLIDIN 1 YL)ETHYL[1,1' BIPHENYL] 4 ACETATE; 8 METHYL 8 AZABICYCLO[3.2.1]OCT 3 YL[1,1' BIPHENYL] 4 ACETATE; ACETIC ACID DERIVATIVE; BUFFER; CYCLOPENTOLATE; ESTER DERIVATIVE; FENBUFEN; FLURBIPROFEN; IPRATROPIUM BROMIDE; NONSTEROID ANTIINFLAMMATORY AGENT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTICHOLINERGIC EFFECT; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; DIGESTIVE SYSTEM ULCER; DRUG POTENCY; DRUG SAFETY; DRUG SCREENING; DRUG STABILITY; DRUG STRUCTURE; DRUG SYNTHESIS; GASTROINTESTINAL ABSORPTION; GASTROINTESTINAL TOXICITY; INHIBITION KINETICS; NONHUMAN; PAW EDEMA; PH; RAT; STOMACH ACID SECRETION; STOMACH MOTILITY; STOMACH PH;

ACETIC ACID; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CHEMISTRY, PHARMACEUTICAL; ESTERS; FEMALE; FLURBIPROFEN; GASTROINTESTINAL TRACT; HUMANS; HYDROGEN-ION CONCENTRATION; ILEUM; MALE; PHENYLACETATES; RATS; RATS, SPRAGUE-DAWLEY;

EID: 33845868510     PISSN: 16121872     EISSN: 16121880     Source Type: Journal    
DOI: 10.1002/cbdv.200690125     Document Type: Article

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