Phosphorylation of Gα11 protein contributes to agonist-induced desensitization of 5-HT2A receptor signaling

Molecular Pharmacology

Volumn 71, Issue 1, 2007, Pages 303-313

  Shi, Ju ^a   Zemaitaitis, Bozena ^a   Muma, Nancy A ^a  

^a LOYOLA UNIVERSITY CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2,5 DIMETHOXY 4 METHYLAMPHETAMINE; G PROTEIN COUPLED RECEPTOR; INOSITOL PHOSPHATE; PROTEIN KINASE C; SERINE; SEROTONIN 2A AGONIST; SEROTONIN 2A RECEPTOR; SEROTONIN 2C AGONIST; SEROTONIN 2C RECEPTOR; THREONINE; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; RECOMBINANT PROTEIN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DESENSITIZATION; DRUG MECHANISM; IMMUNOPRECIPITATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; CELL LINE; CHEMISTRY; GENETIC TRANSFECTION; GENETICS; HUMAN; METABOLISM; MOLECULAR GENETICS; NERVE CELL; PHOSPHORYLATION; PHYSIOLOGY; SIGNAL TRANSDUCTION; SINGLE NUCLEOTIDE POLYMORPHISM; SITE DIRECTED MUTAGENESIS;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; CELL LINE; GTP-BINDING PROTEIN ALPHA SUBUNITS, GQ-G11; HUMANS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; NEURONS; PHOSPHORYLATION; POLYMORPHISM, SINGLE NUCLEOTIDE; RECEPTOR, SEROTONIN, 5-HT2A; RECOMBINANT PROTEINS; SERINE; SIGNAL TRANSDUCTION; THREONINE; TRANSFECTION;

EID: 33845867948     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.106.028241     Document Type: Article

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