메뉴 건너뛰기




Volumn 100, Issue 2, 2007, Pages 437-445

Tau exon 6 is regulated by an intricate interplay of trans factors and cis elements, including multiple branch points

Author keywords

Alternative splicing; cis regulatory elements; Cryptic splice site; Microtubule associated protein tau; Myotonic dystrophy; Trans splicing regulators

Indexed keywords

TAU PROTEIN;

EID: 33845783753     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2006.04252.x     Document Type: Article
Times cited : (12)

References (35)
  • 1
    • 10944272640 scopus 로고    scopus 로고
    • Tau gene alternative splicing: Expression patterns, regulation and modulation of function in normal brain and neurodegenerative diseases
    • Andreadis A. (2005) Tau gene alternative splicing: expression patterns, regulation and modulation of function in normal brain and neurodegenerative diseases. Biochim. Biophys. Acta 1739, 91-103.
    • (2005) Biochim. Biophys. Acta , vol.1739 , pp. 91-103
    • Andreadis, A.1
  • 2
    • 0026488111 scopus 로고
    • Structure and novel exons of the human tau gene
    • Andreadis A., Brown W. M. and Kosik K. (1992) Structure and novel exons of the human tau gene. Biochemistry 31, 10 626-10 633.
    • (1992) Biochemistry , vol.31 , pp. 10626-10633
    • Andreadis, A.1    Brown, W.M.2    Kosik, K.3
  • 3
    • 0027300702 scopus 로고
    • The exon trapping assay partly discriminates against alternatively spliced exons
    • Andreadis A., Nisson P., Kosik K. S. and Watkins P. (1993) The exon trapping assay partly discriminates against alternatively spliced exons. Nucleic Acids Res. 21, 2217-2221.
    • (1993) Nucleic Acids Res. , vol.21 , pp. 2217-2221
    • Andreadis, A.1    Nisson, P.2    Kosik, K.S.3    Watkins, P.4
  • 4
    • 0013394889 scopus 로고    scopus 로고
    • Mechanisms of alternative pre-mRNA splicing
    • Black D. L. (2003) Mechanisms of alternative pre-mRNA splicing. Annu. Rev. Biochem. 72, 291-336.
    • (2003) Annu. Rev. Biochem. , vol.72 , pp. 291-336
    • Black, D.L.1
  • 5
    • 0034161419 scopus 로고    scopus 로고
    • Exonic splicing enhancers: Mechanism of action, diversity and role in human genetic diseases
    • Blencowe B. J. (2000) Exonic splicing enhancers: mechanism of action, diversity and role in human genetic diseases. Trends Biochem. Sci. 25, 106-110.
    • (2000) Trends Biochem. Sci. , vol.25 , pp. 106-110
    • Blencowe, B.J.1
  • 6
    • 10944241542 scopus 로고    scopus 로고
    • Tau alteration and neuronal degeneration in tauopathies: Mechanisms and models
    • Brandt R., Hundelt M. and Shahani N. (2005) Tau alteration and neuronal degeneration in tauopathies: mechanisms and models. Biochim. Biophys. Acta 1739, 331-354.
    • (2005) Biochim. Biophys. Acta , vol.1739 , pp. 331-354
    • Brandt, R.1    Hundelt, M.2    Shahani, N.3
  • 7
    • 0026566108 scopus 로고
    • Molecular basis of myotonic dystrophy: Expansion of a trinucleotide (CTG) repeat at the 3′ end of a transcript encoding a protein kinase family member
    • Brook J. D., McCurrach M. E., Harley H. G. et al. (1992) Molecular basis of myotonic dystrophy: expansion of a trinucleotide (CTG) repeat at the 3′ end of a transcript encoding a protein kinase family member. Cell 68, 799-808.
    • (1992) Cell , vol.68 , pp. 799-808
    • Brook, J.D.1    McCurrach, M.E.2    Harley, H.G.3
  • 8
    • 0036512117 scopus 로고    scopus 로고
    • Messenger-RNA-binding proteins and the messages they carry
    • Dreyfuss G., Kim V. N. and Kataoka N. (2002) Messenger-RNA-binding proteins and the messages they carry. Nat. Rev. Mol. Cell Biol. 3, 195-205.
    • (2002) Nat. Rev. Mol. Cell Biol. , vol.3 , pp. 195-205
    • Dreyfuss, G.1    Kim, V.N.2    Kataoka, N.3
  • 9
    • 0036537492 scopus 로고    scopus 로고
    • Three proteins, MBNL, MBLL and MBXL, co-localize in vivo with nuclear foci of expanded-repeat transcripts in DM1 and DM2 cells
    • Fardaei M., Rogers M. T., Thorpe H. M., Hamshere M. G. and Harper P. S. and. Brook J. D. (2002) Three proteins, MBNL, MBLL and MBXL, co-localize in vivo with nuclear foci of expanded-repeat transcripts in DM1 and DM2 cells. Hum. Mol. Genet. 11, 805-814.
    • (2002) Hum. Mol. Genet. , vol.11 , pp. 805-814
    • Fardaei, M.1    Rogers, M.T.2    Thorpe, H.M.3    Hamshere, M.G.4    Harper, P.S.5    Brook, J.D.6
  • 10
    • 11144258263 scopus 로고    scopus 로고
    • Mutations causing neurodegenerative tauopathies
    • Goedert M. and Jakes R. (2005) Mutations causing neurodegenerative tauopathies. Biochim. Biophys. Acta 1739, 240-250.
    • (2005) Biochim. Biophys. Acta , vol.1739 , pp. 240-250
    • Goedert, M.1    Jakes, R.2
  • 11
    • 0033835333 scopus 로고    scopus 로고
    • Sorting out the complexity of SR protein functions
    • Graveley B. R. (2000) Sorting out the complexity of SR protein functions. RNA 6, 1197-1211.
    • (2000) RNA , vol.6 , pp. 1197-1211
    • Graveley, B.R.1
  • 12
    • 0344074646 scopus 로고    scopus 로고
    • Regulated tissue-specific expression of antagonistic pre-mRNA splicing factors
    • Hanamura A., Cáceres J. F., Mayeda A., Franza B. R. Jr and Krainer A. R. (1998) Regulated tissue-specific expression of antagonistic pre-mRNA splicing factors. RNA 4, 430-444.
    • (1998) RNA , vol.4 , pp. 430-444
    • Hanamura, A.1    Cáceres, J.F.2    Mayeda, A.3    Franza Jr., B.R.4    Krainer, A.R.5
  • 13
    • 0023877583 scopus 로고
    • Unusual branch point selection in processing of human growth hormone pre-mRNA
    • Hartmuth K. and Barta A. (1988) Unusual branch point selection in processing of human growth hormone pre-mRNA. Mol. Cell Biol. 8, 2011-2020.
    • (1988) Mol. Cell Biol. , vol.8 , pp. 2011-2020
    • Hartmuth, K.1    Barta, A.2
  • 14
    • 0037101846 scopus 로고    scopus 로고
    • hnRNP-G promotes exon 7 inclusion of survival motor neuron (SMN) via direct interaction with Htra2-β1
    • Hofmann Y. and Wirth B. (2002) hnRNP-G promotes exon 7 inclusion of survival motor neuron (SMN) via direct interaction with Htra2-β1. Hum. Mol. Genet. 11, 2037-2049.
    • (2002) Hum. Mol. Genet. , vol.11 , pp. 2037-2049
    • Hofmann, Y.1    Wirth, B.2
  • 15
    • 11044233708 scopus 로고    scopus 로고
    • Myotonic dystrophy type 1 is associated with nuclear foci of mutant RNA, sequestration of muscleblind proteins and deregulated alternative splicing in neurons
    • Jiang H., Mankodi A., Swanson M. S., Moxley R. T. and Thornton C. A. (2004) Myotonic dystrophy type 1 is associated with nuclear foci of mutant RNA, sequestration of muscleblind proteins and deregulated alternative splicing in neurons. Hum. Mol. Genet. 13, 3079-3088.
    • (2004) Hum. Mol. Genet. , vol.13 , pp. 3079-3088
    • Jiang, H.1    Mankodi, A.2    Swanson, M.S.3    Moxley, R.T.4    Thornton, C.A.5
  • 17
    • 0028881190 scopus 로고
    • Cell type-specific expression of hnRNP proteins
    • Kamma H., Portman D. S. and Dreyfuss G. (1995) Cell type-specific expression of hnRNP proteins. Exp. Cell Res. 221, 187-196.
    • (1995) Exp. Cell Res. , vol.221 , pp. 187-196
    • Kamma, H.1    Portman, D.S.2    Dreyfuss, G.3
  • 18
    • 0029812945 scopus 로고    scopus 로고
    • Tau bind to the distal axon early in development of polarity in a microtubule- and microfilament-dependent manner
    • Kempf M., Clement A., Faissner A., Lee G. and Brandt R. (1996) Tau bind to the distal axon early in development of polarity in a microtubule- and microfilament-dependent manner. J. Neurosci. 16, 5583-5592.
    • (1996) J. Neurosci. , vol.16 , pp. 5583-5592
    • Kempf, M.1    Clement, A.2    Faissner, A.3    Lee, G.4    Brandt, R.5
  • 20
    • 20444368053 scopus 로고    scopus 로고
    • Neuronal proteins custom designed by alternative splicing
    • Lipscombe D. (2005) Neuronal proteins custom designed by alternative splicing. Curr. Opin. Neurobiol. 15, 358-363.
    • (2005) Curr. Opin. Neurobiol. , vol.15 , pp. 358-363
    • Lipscombe, D.1
  • 21
    • 3142695169 scopus 로고    scopus 로고
    • Tau isoforms which contain the domain encoded by exon 6 and their role in neurite elongation
    • Luo M. H., Leski M. L. and Andreadis A. (2004a) Tau isoforms which contain the domain encoded by exon 6 and their role in neurite elongation. J. Cell Biochem. 91, 880-895.
    • (2004) J. Cell Biochem. , vol.91 , pp. 880-895
    • Luo, M.H.1    Leski, M.L.2    Andreadis, A.3
  • 22
    • 3142704290 scopus 로고    scopus 로고
    • Novel isoforms of tau that lack the microtubule-binding domain
    • Luo M. H., Tse S. W., Memmott J. and Andreadis A. (2004b) Novel isoforms of tau that lack the microtubule-binding domain. J. Neurochem. 90, 340-351.
    • (2004) J. Neurochem. , vol.90 , pp. 340-351
    • Luo, M.H.1    Tse, S.W.2    Memmott, J.3    Andreadis, A.4
  • 23
    • 10044247416 scopus 로고    scopus 로고
    • Characterization of the pattern of cognitive impairment in myotonic dystrophy type 1
    • Modoni A., Silvestri G., Pomponi M. G., Mangiola F., Tonali P. A. and Marra C. (2004) Characterization of the pattern of cognitive impairment in myotonic dystrophy type 1. Arch. Neurol. 61, 1943-1947.
    • (2004) Arch. Neurol. , vol.61 , pp. 1943-1947
    • Modoni, A.1    Silvestri, G.2    Pomponi, M.G.3    Mangiola, F.4    Tonali, P.A.5    Marra, C.6
  • 24
    • 0037669004 scopus 로고    scopus 로고
    • HnRNP G and Tra2β: Opposite effects on splicing matched by antagonism in RNA binding
    • Nasim M. T., Chernova T. K., Chowdhury H. M., Yue B. G. and Eperon I. C. (2003) HnRNP G and Tra2β: opposite effects on splicing matched by antagonism in RNA binding. Hum. Mol. Genet. 12, 1337-1348.
    • (2003) Hum. Mol. Genet. , vol.12 , pp. 1337-1348
    • Nasim, M.T.1    Chernova, T.K.2    Chowdhury, H.M.3    Yue, B.G.4    Eperon, I.C.5
  • 25
    • 0031155892 scopus 로고    scopus 로고
    • Microtubule-associated proteins (MAPs) in the peripheral nervous system during development and regeneration
    • Nuñez J. and Fischer I. (1997) Microtubule-associated proteins (MAPs) in the peripheral nervous system during development and regeneration. J. Mol. Neurosci. 8, 207-222.
    • (1997) J. Mol. Neurosci. , vol.8 , pp. 207-222
    • Nuñez, J.1    Fischer, I.2
  • 26
    • 22544469467 scopus 로고    scopus 로고
    • Silencers regulate both constitutive and alternative splicing events in mammals
    • Pozzoli U. and Sironi M. (2005) Silencers regulate both constitutive and alternative splicing events in mammals. Cell. Mol. Life Sci. 62, 1579-1604.
    • (2005) Cell. Mol. Life Sci. , vol.62 , pp. 1579-1604
    • Pozzoli, U.1    Sironi, M.2
  • 27
    • 0033019048 scopus 로고    scopus 로고
    • Selection and characterization of pre-mRNA splicing enhancers: Identification of novel SR protein-specific enhancer sequences
    • Schaal T. D. and Maniatis T. (1997) Selection and characterization of pre-mRNA splicing enhancers: identification of novel SR protein-specific enhancer sequences. Mol. Cell Biol. 19, 1705-1719.
    • (1997) Mol. Cell Biol. , vol.19 , pp. 1705-1719
    • Schaal, T.D.1    Maniatis, T.2
  • 29
    • 33646537438 scopus 로고    scopus 로고
    • Pre-messenger RNA processing and its regulation: A genomic perspective
    • Soller M. (2006) Pre-messenger RNA processing and its regulation: a genomic perspective. Cell Mol. Life Sci. 63, 96-819.
    • (2006) Cell Mol. Life Sci. , vol.63 , pp. 96-819
    • Soller, M.1
  • 31
    • 0035896610 scopus 로고    scopus 로고
    • RNA CUG repeats sequester CUGBP1 and alter protein levels and activity of CUGBP1
    • Timchenko N. A., Cai Z. J., Welm A. L., Reddy S. and Aschenko L. T. (2001) RNA CUG repeats sequester CUGBP1 and alter protein levels and activity of CUGBP1. J. Biol. Chem. 276, 7820-7826.
    • (2001) J. Biol. Chem. , vol.276 , pp. 7820-7826
    • Timchenko, N.A.1    Cai, Z.J.2    Welm, A.L.3    Reddy, S.4    Aschenko, L.T.5
  • 32
    • 1442348429 scopus 로고    scopus 로고
    • Tau exon 10, whose mis-splicing causes frontotemporal dementia, is regulated by an intricate interplay of cis elements and trans factors
    • Wang J., Gao Q. S., Wang Y., Lafyatis R., Stamm S. and Andreadis A. (2004) Tau exon 10, whose mis-splicing causes frontotemporal dementia, is regulated by an intricate interplay of cis elements and trans factors. J. Neurochem. 88, 1078-1090.
    • (2004) J. Neurochem. , vol.88 , pp. 1078-1090
    • Wang, J.1    Gao, Q.S.2    Wang, Y.3    Lafyatis, R.4    Stamm, S.5    Andreadis, A.6
  • 33
    • 17144427268 scopus 로고    scopus 로고
    • Tau exons 2 and 10, which are misregulated in neurodegenerative diseases, are partly regulated by silencers which bind a SRp30c. SRp55 complex that either recruits or antagonizes htra2β1
    • Wang Y., Wang J., Gao L., Lafyatis R., Stamm S. and Andreadis A. (2005) Tau exons 2 and 10, which are misregulated in neurodegenerative diseases, are partly regulated by silencers which bind a SRp30c. SRp55 complex that either recruits or antagonizes htra2β1. J. Biol. Chem. 280, 14 230-14 239.
    • (2005) J. Biol. Chem. , vol.280 , pp. 14230-14239
    • Wang, Y.1    Wang, J.2    Gao, L.3    Lafyatis, R.4    Stamm, S.5    Andreadis, A.6
  • 34
    • 0031906031 scopus 로고    scopus 로고
    • Splicing of a regulated exon reveals additional complexity in the axonal MAP tau
    • Wei M.-L. and Andreadis A. (1998) Splicing of a regulated exon reveals additional complexity in the axonal MAP tau. J. Neurochem. 70, 1346-1356.
    • (1998) J. Neurochem. , vol.70 , pp. 1346-1356
    • Wei, M.-L.1    Andreadis, A.2
  • 35
    • 0034665939 scopus 로고    scopus 로고
    • The splicing determinants of a regulated exon in the axonal MAP tau reside within the exon and in its upstream intron
    • Wei M.-L., Memmott J., Screaton G. and Andreadis A. (2000) The splicing determinants of a regulated exon in the axonal MAP tau reside within the exon and in its upstream intron. Brain Res. Mol. Brain Res. 80, 207-218.
    • (2000) Brain Res. Mol. Brain Res. , vol.80 , pp. 207-218
    • Wei, M.-L.1    Memmott, J.2    Screaton, G.3    Andreadis, A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.