Corpus cavernosum electromyography with revised methodology: An explorative study in patients with erectile dysfunction and men with reported normal erectile function

Journal of Sexual Medicine

Volumn 4, Issue 1, 2007, Pages 191-198

  Meuleman, Eric ^a   Jiang, Xiaogang ^b   Holsheimer, January ^c   Wagner, Gorm ^d   Knipscheer, Ben ^b   Wijkstra, Hessel ^e  

^a VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^b RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^c UNIVERSITY OF TWENTE   (Netherlands)

^d The Capital Region   (Denmark)

^e ACADEMIC MEDICAL CENTER   (Netherlands)

Author keywords

CC EMG; Corpus cavernosum; Diagnosis; Electromyography; Erectile dysfunction; Smooth muscle

Indexed keywords

ADULT; AGED; AMPLITUDE MODULATION; ARTERIAL INSUFFICIENCY; ARTICLE; CARDIOVASCULAR DISEASE; COMORBIDITY; CONTROLLED STUDY; CORPUS CAVERNOSUM; CORRELATION COEFFICIENT; DIAGNOSTIC VALUE; DIFFERENTIAL DIAGNOSIS; DISEASE SEVERITY; ELECTRODE; ELECTROMYOGRAPHY; ERECTILE DYSFUNCTION; EXPLORATORY RESEARCH; HUMAN; MAJOR CLINICAL STUDY; MALE; PENILE FIBROSIS; PENIS ARTERY; PENIS ERECTION; PRIORITY JOURNAL; PROSTATE CANCER; RADICAL RETROPUBIC PROSTATECTOMY;

EID: 33845778456     PISSN: 17436095     EISSN: 17436109     Source Type: Journal    
DOI: 10.1111/j.1743-6109.2006.00403.x     Document Type: Article

References (32)

1. Andersson KE, Wagner G. Physiology of penile erection. Physiol Rev 1995; 75: 191-236.
2. Saenz de Tejada I, Angulo J, Cellek S, Gonzalez-Cadavid N, Heaton J, Pickard R, Simonsen U. Physiology of erectile function. J Sex Med 2004; 1: 254-65.
3. Meuleman EJH, Naudin ten Cate L, de Wilde PCM, Vooys GP, Debruyne FMJ. The use of penile biopsies in the detection of end organ disease: A histomorphometric study of the human cavernous body. Int J Impot Res 1990; 2: 161-7.
4. Meuleman EJ. Investigations in erectile dysfunction. Curr Opin Urol 2003; 13: 411-16.
5. Diemont WL, Meuleman EJ. Neurological testing in erectile dysfunction. J Androl 1997; 18: 345-50.
6. Sasso F, Gulino G, Alcini A, Alcini E. Early experience of corpus cavernosum electromyography in impotent patients after radical cystoprostatectomy. Eur Urol 1996; 29: 466-9.
7. Wagner G, Gerstenberg TC, Levin RJ. Electrical activity of corpus cavernosum during flaccidity and erection of the human penis. J Urol 1989; 142: 723-5.
8. Truss MC, Djamilian MH, Tan HK, Hinrichs H, Feistner H, Stief CG, Jonas U. Single potential analysis of cavernous electrical activity. Four years' experience in more than 500 patients with erectile dysfunction. Eur Urol 1993; 24: 358-65.
9. Merckx L, Gerstenberg TC, Da Silva JP, Portner M, Stief CG. A consensus on the normal characteristics of corpus cavernosum EMG. Int J Impot Res 1996; 8: 75-9.
10. Fabra M, Frieling A, Porst H, Schneider E. Single potential analysis of corpus cavernosum electromyography for the assessment of erectile dysfunction: Provocation, reproducibility and age dependence-Findings in 36 healthy volunteers and 324 patients. J Urol 1997; 158: 444-50.
11. Sattar AA, Merckx LA, Wespes E. Penile electromyography and its smooth muscle content. interpretation of 25 impotent patients. J Urol 1996; 155: 909-12.
12. Merckx L, Schmedding E, De Bruyne R, Stief C, Keuppens F. Penile electromyography in the diagnosis of impotence. Eur Urol 1994; 25: 124-30.
13. Stief CG, Djamilian M, Truss MC, Tan H, Thon WF, Jonas U. Prognostic factors for the postoperative outcome of penile venous surgery for venogenic erectile dysfunction. J Urol 1994; 151: 880-3.
14. Jiang XG, Speel TG, Wagner G, Meuleman EJ, Wijkstra H. The value of corpus cavernosum electromyography in erectile dysfunction: Current status and future prospect. Eur Urol 2003; 43: 211-8.
15. Jiang XG, Wijkstra H, Meuleman EJH, Wagner G. The methodology of corpus cavernosum electromyography revisited. Eur Urol 2004; 46: 370-6.
16. Jiang X, Holsheimer J, Wagner G, Mulders P, Wijkstra H, Meuleman E. A reproducibility study of corpus cavernosum electromyography in young healthy volunteers under controlled conditions. J Sex Med 2007; 4: 183-90.
17. Speel TG, van Langen H, Wijkstra H, Meuleman EJ. Penile duplex pharmaco-ultrasonography revisited: Revalidation of the parameters of the cavernous arterial response. J Urol 2003; 169: 216-20.
18. Lewis RW, Fugl-Meyer KS, Bosch R, Fugl-Meyer AR, Laumann EO, Lizza E, Martin-Morales A. Epidemiology/risk factors of sexual dysfunction. J Sex Med 2004; 1: 35-9.
19. Houk JC, Dessem DA, Miller LE, Sybirska EH. Correlation and spectral analysis of relations between single unit discharge and muscle activities. J Neurosci Meth 1987; 21: 201-24.
20. Persson C, Diederichs W, Lue TF, Yen TS, Fishman IJ, McLin PH, Tanagho EA. Correlation of altered penile ultrastructure with clinical arterial evaluation. J Urol 1989; 142: 1462-8.
21. Wespes E, Goes PM, Schiffmann S, Depierreux M, Vanderhaeghen JJ, Schulman CC. Computerized analysis of smooth muscle fibers in potent and impotent patients. J Urol 1991; 146: 1015-7.
22. Burnett AL. Erectile dysfunction following radical prostatectomy. JAMA 2005; 293: 2648-53.
23. Yilmaz U, Ellis W, Lange P, Yang C. Evoked cavernous activity: Measuring penile autonomic innervation following pelvic surgery. Int J Impot Res 2006; 18: 296-301.
24. Moreland RB. Is there a role of hypoxemia in penile fibrosis: A viewpoint presented to the Society for the Study of Impotence. Int J Impot Res 1998; 10: 113-20.
25. Saenz de Tejada I, Angulo J, Cellek S, Gonzalez-Cadavid N, Heaton J, Pickard R, Simonsen U. Pathophysiology of erectile dysfunction. J Sex Med 2005; 2: 26-39.
26. Paick JS, Goldsmith PC, Barta AK, Nunes L, Padula CA, Lue TF. Relationship between venous incompetence and cavernous nerve injury: Ultrastructural alteration of cavernous smooth muscle in the neurotomized dog. Int J Impot Res 1991; 3: 173-84.
27. Vickers MA, Wright EA. Erectile dysfunction in the patient with diabetes mellitus. Am J Manag Care 2004; 10: S3-11.
28. Spollett GR. Assessment and management of erectile dysfunction in men with diabetes. Diabetes Educ 1999; 25: 65-73.
29. Iacono F, Giannella R, Somma P, Manno G, Fusco F, Mirone V. Histological alterations in cavernous tissue after radical prostatectomy. J Urol 2005; 173: 1673-6.
30. Jiang X, Meuleman EJ, Wijkstra H, Wagner G. Corpus cavernosum electromyography during morning naps in healthy volunteers: Further evidence that corpus cavernosum potentials reflect sympathetically mediated activity. J Urol 2005; 174: 1917.
31. Hoppner CK, Stief CG, Jonas U, Mandrek K, Noack T, Golenhofen K. Electrical and chemical control of smooth muscle activity of rabbit corpus cavernosum in vitro. Urology 1996; 48: 512-18.
32. Nilsson H, Aalkjaer C. Vasomotion: Mechanisms and physiological importance. Mol Interv 2003; 3: 51.