-
1
-
-
0030721001
-
Isoenzymes of protein kinase C: Differential involvement in apoptosis and pathogenesis
-
Deacon EM, Pongracz J, Griffiths G, Lord JM. Isoenzymes of protein kinase C: differential involvement in apoptosis and pathogenesis. Mol Pathol 1997;50: 124-31.
-
(1997)
Mol Pathol
, vol.50
, pp. 124-131
-
-
Deacon, E.M.1
Pongracz, J.2
Griffiths, G.3
Lord, J.M.4
-
2
-
-
0029442869
-
Potential for protein kinase C inhibitors in cancer therapy
-
Philip PA, Harris AL. Potential for protein kinase C inhibitors in cancer therapy. Cancer Treat Res 1995; 78:3-27.
-
(1995)
Cancer Treat Res
, vol.78
, pp. 3-27
-
-
Philip, P.A.1
Harris, A.L.2
-
4
-
-
0000939974
-
Elevation of protein kinase A and protein kinase C activities in malignant as compared with normal human breast tissue
-
Gordge PC, Hulme MJ, Clegg RA, Miller WR. Elevation of protein kinase A and protein kinase C activities in malignant as compared with normal human breast tissue. Eur J Cancer 1996;32A:2120-6.
-
(1996)
Eur J Cancer
, vol.32 A
, pp. 2120-2126
-
-
Gordge, P.C.1
Hulme, M.J.2
Clegg, R.A.3
Miller, W.R.4
-
5
-
-
0024323584
-
Elevated protein kinase C expression in human breast tumor biopsies relative to normal breast tissue
-
O'Brian C, Vogel VG, Singletary SE, Ward NE. Elevated protein kinase C expression in human breast tumor biopsies relative to normal breast tissue. Cancer Res 1989;49:3215-7.
-
(1989)
Cancer Res
, vol.49
, pp. 3215-3217
-
-
O'Brian, C.1
Vogel, V.G.2
Singletary, S.E.3
Ward, N.E.4
-
7
-
-
0033386539
-
Protein kinase C targeting in antineoplastic targeting in antineoplastic treatment strategies
-
Jarvis WD, Grant S. Protein kinase C targeting in antineoplastic targeting in antineoplastic treatment strategies. Invest New Drugs 1999;17:227-40.
-
(1999)
Invest New Drugs
, vol.17
, pp. 227-240
-
-
Jarvis, W.D.1
Grant, S.2
-
8
-
-
0029971406
-
Antineoplastic agents. 340. Isolation and structural eludication of bryostatins 16-18
-
Pettit GR, Gao F, Blumberg PM, et al. Antineoplastic agents. 340. Isolation and structural eludication of bryostatins 16-18. J Nat Prod 1996;59:286-9.
-
(1996)
J Nat Prod
, vol.59
, pp. 286-289
-
-
Pettit, G.R.1
Gao, F.2
Blumberg, P.M.3
-
9
-
-
0346096818
-
Bryostatin 1: A novel PKC inhibitor in clinical development
-
Kortmansky J, Schwartz GK. Bryostatin 1: a novel PKC inhibitor in clinical development. Cancer Invest 2003;21:924-36.
-
(2003)
Cancer Invest
, vol.21
, pp. 924-936
-
-
Kortmansky, J.1
Schwartz, G.K.2
-
10
-
-
0029084804
-
A phase I trial of bryostatin 1 in patients with advanced malignancy using a 24 hour intravenous infusion
-
Jayson GC, Crowther D, Prendiville J, et al. A phase I trial of bryostatin 1 in patients with advanced malignancy using a 24 hour intravenous infusion. Br J Cancer 1995;72:461-8.
-
(1995)
Br J Cancer
, vol.72
, pp. 461-468
-
-
Jayson, G.C.1
Crowther, D.2
Prendiville, J.3
-
11
-
-
0027489606
-
A phase I study of bryostatin 1: Assessment of interleukin 6 and tumor necrosis factor α induction in vivo
-
The Cancer Research Campaign Phase I Committee
-
Philip PA, Rea D, Thavsau P, et al. A phase I study of bryostatin 1: assessment of interleukin 6 and tumor necrosis factor α induction in vivo. The Cancer Research Campaign Phase I Committee. J Natl Cancer Inst 1993;85:1812-8.
-
(1993)
J Natl Cancer Inst
, vol.85
, pp. 1812-1818
-
-
Philip, P.A.1
Rea, D.2
Thavsau, P.3
-
12
-
-
0035139097
-
A phase II trial of bryostatin I in the treatment of metastatic colorectal cancer
-
Zonder JA, Shields AF, Zalupski M, et al. A phase II trial of bryostatin I in the treatment of metastatic colorectal cancer. Clin Cancer Res 2001;7:38-42.
-
(2001)
Clin Cancer Res
, vol.7
, pp. 38-42
-
-
Zonder, J.A.1
Shields, A.F.2
Zalupski, M.3
-
13
-
-
0034254971
-
A phase II trial of bryostatin 1 for patients with metastatic renal call carcinoma
-
Pagliaro L, Daliani D, Amato R, et al. A phase II trial of bryostatin 1 for patients with metastatic renal call carcinoma. Cancer 2000;89:615-8.
-
(2000)
Cancer
, vol.89
, pp. 615-618
-
-
Pagliaro, L.1
Daliani, D.2
Amato, R.3
-
14
-
-
0031760304
-
A phase II study of bryostatin 1 in metastatic malignant melanoma
-
Propper DJ, Macaulay C, O'Byrne KJ, et al. A phase II study of bryostatin 1 in metastatic malignant melanoma. Br J Cancer 1998;78:1337-41.
-
(1998)
Br J Cancer
, vol.78
, pp. 1337-1341
-
-
Propper, D.J.1
Macaulay, C.2
O'Byrne, K.J.3
-
15
-
-
0034851020
-
Phase II studies of bryostatin 1 in patients with advanced sarcoma and advanced head and neck cancer
-
Brockstein B, Samuels B, Humerickhouse R, et al. Phase II studies of bryostatin 1 in patients with advanced sarcoma and advanced head and neck cancer. Invest New Drugs 2001;19:249-54.
-
(2001)
Invest New Drugs
, vol.19
, pp. 249-254
-
-
Brockstein, B.1
Samuels, B.2
Humerickhouse, R.3
-
16
-
-
0141787046
-
Sensitization of human breast cancer cells to gemcitabine by the protein kinase C modulator bryostatin 1
-
Ali S, Aranha O, Li Y, Pettit GR, Sarkar FH, Philip PA. Sensitization of human breast cancer cells to gemcitabine by the protein kinase C modulator bryostatin 1. Cancer Chemother Pharmacol 2003;52: 235-46.
-
(2003)
Cancer Chemother Pharmacol
, vol.52
, pp. 235-246
-
-
Ali, S.1
Aranha, O.2
Li, Y.3
Pettit, G.R.4
Sarkar, F.H.5
Philip, P.A.6
-
17
-
-
0025978216
-
A phase I clinical, plasma, and cellular pharmacology study of gemcitabine
-
Abbruzzese JL, Grunewald R, Weeks EA, et al. A phase I clinical, plasma, and cellular pharmacology study of gemcitabine. J Clin Oncol 1991;9: 491-8.
-
(1991)
J Clin Oncol
, vol.9
, pp. 491-498
-
-
Abbruzzese, J.L.1
Grunewald, R.2
Weeks, E.A.3
-
18
-
-
0030456669
-
Gemcitabine: Safety profile unaffected by starting dose
-
Martin C, Pollera CF. Gemcitabine: safety profile unaffected by starting dose. Int J Clin Pharmacol Res 1996;16:9-18.
-
(1996)
Int J Clin Pharmacol Res
, vol.16
, pp. 9-18
-
-
Martin, C.1
Pollera, C.F.2
-
19
-
-
8244254377
-
Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer; a randomized trial
-
Burris HA III, Moore MJ, Anderson J, et al. Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer; a randomized trial. J Clin Oncol 1997; 15:2403-13.
-
(1997)
J Clin Oncol
, vol.15
, pp. 2403-2413
-
-
Burris III, H.A.1
Moore, M.J.2
Anderson, J.3
-
20
-
-
0028799915
-
Advanced breast cancer: A phase II trial with gemcitabine
-
Carmichael J, Possinger K, Phillip P, et al. Advanced breast cancer: a phase II trial with gemcitabine. J Clin Oncol 1995;13:2431-6.
-
(1995)
J Clin Oncol
, vol.13
, pp. 2431-2436
-
-
Carmichael, J.1
Possinger, K.2
Phillip, P.3
-
21
-
-
85047686771
-
Role of gemcitabine in cancer therapy
-
Toschi L, Finocchiaro G, Bartolini S, Gioia V, Cappusso F. Role of gemcitabine in cancer therapy. Future Oncol 2005;1:7-17.
-
(2005)
Future Oncol
, vol.1
, pp. 7-17
-
-
Toschi, L.1
Finocchiaro, G.2
Bartolini, S.3
Gioia, V.4
Cappusso, F.5
-
22
-
-
0033913982
-
Gemcitabine plus best supportive care (BSC) versus BSC in inoperable non-small cell lung cancer - A randomized trial with quality of life as the primary outcome
-
UK NSCLC Gemcitabine. Non-Small Cell Lung Cancer
-
Anderson H, Hopwood P, Stephens RJ, et al. Gemcitabine plus best supportive care (BSC) versus BSC in inoperable non-small cell lung cancer-a randomized trial with quality of life as the primary outcome. UK NSCLC Gemcitabine. Non-Small Cell Lung Cancer Br J Cancer 2000;83:447-53.
-
(2000)
Br J Cancer
, vol.83
, pp. 447-453
-
-
Anderson, H.1
Hopwood, P.2
Stephens, R.J.3
-
23
-
-
0023253596
-
Bryostatin 1, an activator of protein kinase C, inhibits tumor promotion by phorbol esters in SENCAR mouse skin
-
Hennings H, Blumberg PM, Pettit GR, Herald CL, Shores R, Yuspa SH. Bryostatin 1, an activator of protein kinase C, inhibits tumor promotion by phorbol esters in SENCAR mouse skin. Carcinogenesis 1987; 8:1343-6.
-
(1987)
Carcinogenesis
, vol.8
, pp. 1343-1346
-
-
Hennings, H.1
Blumberg, P.M.2
Pettit, G.R.3
Herald, C.L.4
Shores, R.5
Yuspa, S.H.6
-
24
-
-
0035992301
-
Phase I trial and correlative larobatory studies of bryostatin 1 (NSC 339555) and high-dose 1-β-D-arabionfuranosycytosine in patients with refractory acute leukemia
-
Cragg LH, Andreeff M, Feldman E, et al. Phase I trial and correlative larobatory studies of bryostatin 1 (NSC 339555) and high-dose 1-β-D-arabionfuranosycytosine in patients with refractory acute leukemia. Clin Cancer Res 2002;8:2123-33.
-
(2002)
Clin Cancer Res
, vol.8
, pp. 2123-2133
-
-
Cragg, L.H.1
Andreeff, M.2
Feldman, E.3
-
25
-
-
0347995049
-
Phase I and correlative study of combination bryostatin 1 and vincristine in relapsed B-cell malignancies
-
Dowlati A, Lazarus HM, Hartman P, et al. Phase I and correlative study of combination bryostatin 1 and vincristine in relapsed B-cell malignancies. Clin Cancer Res 2003;9:5929-35.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 5929-5935
-
-
Dowlati, A.1
Lazarus, H.M.2
Hartman, P.3
-
26
-
-
0023783698
-
Comparison of the cellular pharmacokinetics and toxicity of 2′,2′-difluorodeoxycytidine and 1-β-D-arabinofuranosylcytosine
-
Heinemann V, Hertel LW, Grindley GB, Plunkett W. Comparison of the cellular pharmacokinetics and toxicity of 2′,2′- difluorodeoxycytidine and 1-β-D-arabinofuranosylcytosine. Cancer Res 1988;48: 4024-31.
-
(1988)
Cancer Res
, vol.48
, pp. 4024-4031
-
-
Heinemann, V.1
Hertel, L.W.2
Grindley, G.B.3
Plunkett, W.4
|