Preliminary multi-institutional prospective pathologic and molecular studies support preservation of sublevel IIB and level IV for laryngeal squamous carcinoma with clinically negative neck

European Archives of Oto-Rhino-Laryngology

Volumn 264, Issue 2, 2007, Pages 111-114

  Ferlito, Alfio ^a   Silver, Carl E ^b   Suárez, Carlos ^c,d   Rinaldo, Alessandra ^a  

^a UNIVERSITY OF UDINE   (Italy)

^b ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^c HOSPITAL UNIVERSITARIO CENTRAL DE ASTURIAS   (Spain)

^d DEPARTAMENTO DE BIOQUÍMICA Y BIOLOGÍA MOLECULAR   (Spain)

Author keywords

Laryngeal squamous carcinoma; Level IV; Molecular analysis; Neck dissection; Sublevel IIB

Indexed keywords

ACCESSORY NERVE; ASPIRATION BIOPSY; BRACHIAL PLEXUS INJURY; CARCINOMA IN SITU; CERVICAL LYMPH NODE; CHYLE; ELECTIVE SURGERY; ELECTROMYOGRAPHY; FISTULA; FROZEN SHOULDER; HISTOPATHOLOGY; HUMAN; IMMUNOHISTOCHEMISTRY; INTERNAL JUGULAR VEIN; LARYNX CARCINOMA; LYMPH NODE METASTASIS; MICROMETASTASIS; NECK DISSECTION; NEEDLE BIOPSY; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; REVIEW; SHOULDER INJURY; SHOULDER PAIN; SQUAMOUS CELL CARCINOMA; STERNOCLEIDOMASTOID MUSCLE; SURGICAL RISK; TISSUE SECTION;

CARCINOMA, SQUAMOUS CELL; FALSE NEGATIVE REACTIONS; GENES, P53; HUMANS; LARYNGEAL NEOPLASMS; LYMPH NODE EXCISION; MOLECULAR BIOLOGY; MULTICENTER STUDIES; NECK DISSECTION; NEOPLASM STAGING; POINT MUTATION; PROSPECTIVE STUDIES;

EID: 33845723528     PISSN: 09374477     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00405-006-0209-5     Document Type: Review

References (22)

1. Robbins KT, Clayman G, Levine PA, Medina J, Sessions R, Shaha A, Som P, Wolf GT (2002) Neck dissection classification update. Revisions proposed by the American Head and Neck Society and the American Academy of Otolaryngology-Head and Neck Surgery. Arch Otolaryngol Head Neck Surg 128:751-758
2. Laverick S, Lowe D, Brown JS, Vaughan ED, Rogers SN (2004) The impact of neck dissection on health-related quality of life. Arch Otolaryngol Head Neck Surg 130:149-154
3. Terrell JE, Welsh DE, Bradford CR, Chepeha DB, Esclamado RM, Hogikyan ND, Wolf GT (2000) Pain, quality of life, and spinal accessory nerve status after neck dissection. Laryngoscope 110:620-626
4. Köybaşioǧlu A, Tokçaer AB, Inal E, Uslu S, Koçak T, Ural A (2006) Accessory nerve function in lateral selective neck dissection with undissected level IIB. ORL J Otorhinolaryngol Relat Spec 68:88-92
5. Elsheikh MN, Rinaldo A, Hamakawa H, Mahfouz ME, Rodrigo JP, Brennan J, Devaney KO, Grandis JR, Ferlito A (2006) Importance of molecular analysis in detecting cervical lymph node metastasis in head and neck squamous cell carcinoma. Head Neck 28:842-849
6. Yamazaki Y, Chiba I, Hirai A, Satoh C, Sakakibara N, Notani K, Iizuka T, Totsuka Y (2005) Clinical value of genetically diagnosed lymph node micrometastasis for patients with oral squamous cell carcinoma. Head Neck 27:676-681
7. Hamakawa H, Fukizumi M, Bao Y, Sumida T, Onishi A, Tanioka H, Sato H, Yumoto E (1999) Genetic diagnosis of micrometastasis based on SCC antigen mRNA in cervical lymph nodes of head and neck cancer. Clin Exp Metastasis 17:593-599
8. Yoshioka S, Fujiwara Y, Sugita Y, Okada Y, Yano M, Tamura S, Yasuda T, Takiguchi S, Shiozaki H, Monden M (2002) Real-time rapid reverse transcriptase-polymerase chain reaction for intraoperative diagnosis of lymph node micrometastasis: clinical application for cervical lymph node dissection in esophageal cancers. Surgery 132:34-40
9. Shores CG, Yin X, Funkhouser W, Yarbrough W (2004) Clinical evaluation of a new molecular method for detection of micrometastases in head and neck squamous cell carcinoma. Arch Otolaryngol Head Neck Surg 130:937-942
10. Hamakawa H, Onishi A, Sumida T, Terakado N, Hino S, Nakashiro KI, Shintani S (2004) Intraoperative real-time genetic diagnosis for sentinel node navigation surgery. Int J Oral Maxillofac Surg 33:670-675
11. Becker MT, Shores CG, Yu KK, Yarbrough WG (2004) Molecular assay to detect metastatic head and neck squamous cell carcinoma. Arch Otolaryngol Head Neck Surg 130:21-27
12. Nieuwenhuis EJ, Jaspars LH, Castelijns JA, Bakker B, Wishaupt RG, Denkers F, Leemans CR, Snow GB, Brakenhoff RH (2003) Quantitative molecular detection of minimal residual head and neck cancer in lymph node aspirates. Clin Cancer Res 9:755-761
13. Ferris RL, Xi L, Raja S, Hunt JL, Wang J, Gooding WE, Kelly L, Ching J, Luketich JD, Godfrey TE (2005) Molecular staging of cervical lymph nodes in squamous cell carcinoma of the head and neck. Cancer Res 65:2147-2156
14. Brennan JA, Mao L, Hruban RH, Boyle JO, Eby YJ, Koch WM, Goodman SN, Sidransky D (1995) Molecular assessment of histopathological staging in squamous-cell carcinoma of the head and neck. N Engl J Med 332:429-435
15. Rinaldo A, Elsheikh MN, Ferlito A, Chone CT, Coskun HH, Köybaşioǧlu A, Esclamado RM, Corlette TH, Talmi YP (2006) Prospective studies of neck dissection specimens support preservation of sublevel IIB for laryngeal squamous carcinoma with clinically negative neck. J Am Coll Surg 202:967-970
16. Köybasioǧlu A, Uslu S, Yilmaz M, Inal E, Ileri F, Asal K (2002) Lymphatic metastasis to the supraretrospinal recess in laryngeal squamous cell carcinoma. Ann Otol Rhinol Laryngol 111:96-99
17. Aydogan LB, Aydogan FK, Uguz A, Soylu L, Tuncer U, Kiroglu MM (2004) Levels IIB and IV involvement in laryngeal carcinoma. Final Program and Abstract Book, 6th Int Conf Head Neck Cancer, Washington, DC: 111 (Poster Session 1, p1-195)
18. Coskun HH, Erisen L, Basut O (2004) Selective neck dissection for clinically N0 neck in laryngeal cancer: is dissection of level IIb necessary? Otolaryngol Head Neck Surg 131:655-659
19. Lim YC, Lee JS, Koo BS, Choi EC (2006) Level IIb lymph node metastasis in laryngeal squamous cell carcinoma. Laryngoscope 116:268-272
20. Elsheikh MN, Mahfouz ME, Salim EI, Elsheikh EA (2006) Molecular assessment of neck dissections supports preserving level IIB lymph nodes in selective neck dissection for laryngeal squamous cell carcinoma with a clinically negative neck. ORL J Otorhinolaryngol Relat Spec 68:177-184
21. Lim YC, Choi EC, Lee JS, Koo BS, Song MH, Shin HA (2006) Is dissection of level IV absolutely necessary in elective lateral neck dissection for clinically N0 laryngeal carcinoma? Oral Oncol 42:102-107
22. Elsheikh MN, Ferlito A, Rinaldo A, Shaha AR, KhaWf A, Copkun HH, Kowalski LP, Medina JE (2006) Do pathologic and molecular analyses of neck dissection specimens justify the preservation of level IV for laryngeal squamous carcinoma with clinically negative neck? J Am Coll Surg 202:320-323