Antigen-induced differential gene expression in lymphocytes and gene expression profile in synovium prior to the onset of arthritis

Autoimmunity

Volumn 39, Issue 8, 2006, Pages 663-673

  Adarichev, Vyacheslav A ^a   Vermes, Csaba ^a   Hanyecz, Anita ^a   Ludanyi, Katalin ^a   Tunyogi Csapo, Miklos ^a   Finnegan, Alison ^a   Mikecz, Katalin ^a   Glant, Tibor T ^a  

^a RUSH UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Affymetrix; Animal model; Autoimmunity; Gene expression; Inflammation; Rheumatoid arthritis

Indexed keywords

ANTIGEN; CHEMOKINE RECEPTOR; CHEMOKINE RECEPTOR CCR2; CHEMOKINE RECEPTOR CCR5; GAMMA INTERFERON; INTERLEUKIN 1; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 16; INTERLEUKIN 17; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 6; MONOCYTE CHEMOTACTIC PROTEIN 1; PROTEOGLYCAN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOIMMUNE DISEASE; CELL MOTILITY; CELL STIMULATION; CLASSIFICATION; COMPLEMENT SYSTEM; CONTROLLED STUDY; DOWN REGULATION; FEMALE; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE FUNCTION; GENE IDENTIFICATION; GENE REPRESSION; GENE SILENCING; IMMUNITY; IMMUNOGLOBULIN GENE; IN VITRO STUDY; INFLAMMATION; LYMPHOCYTE; LYMPHOCYTE ACTIVATION; MOUSE; NONHUMAN; RHEUMATOID ARTHRITIS; SCID MOUSE; SIGNAL TRANSDUCTION; SPLEEN CELL; SYNOVIUM; UPREGULATION;

ADOPTIVE TRANSFER; ANIMALS; ARTHRITIS, EXPERIMENTAL; ARTHRITIS, RHEUMATOID; GENE EXPRESSION; GENE EXPRESSION PROFILING; HUMANS; LYMPHOCYTES; MICE; MICE, INBRED BALB C; MICE, SCID; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; SYNOVIAL MEMBRANE;

EID: 33845706289     PISSN: 08916934     EISSN: 1607842X     Source Type: Journal    
DOI: 10.1080/08916930601062643     Document Type: Article

References (23)

1. Glant, TT and Mikecz, K and Arzoumanian, A and Poole, AR. (1987) Proteoglycan-induced arthritis in BALB/c mice. Clinical features and histopathology Arthritis Rheum, 30, pp. 201-212.
2. Mikecz, K and Glant, TT and Poole, AR. (1987) Immunity to cartilage proteoglycans in BALB/c mice with progressive polyarthritis and ankylosing spondylitis induced by injection of human cartilage proteoglycan Arthritis Rheum, 30, pp. 306-318.
3. Glant, TT and Finnegan, A and Mikecz, K. (2003) Proteoglycan-induced arthritis: Immune regulation, cellular mechanisms and genetics Crit Rev Immunol, 23, pp. 199-250.
4. Mikecz, K and Glant, TT and Buzás, E and Poole, AR. (1990) Proteoglycan-induced polyarthritis and spondylitis adoptively transferred to naive (nonimmunized) BALB/c mice Arthritis Rheum, 33, pp. 866-876.
5. Mikecz, K and Glant, TT. (1994) Migration and homing of lymphocytes to lymphoid and synovial tissues in proteoglycan-induced murine arthritis Arthritis Rheum, 37, pp. 1395-1403.
6. Bárdos, T and Mikecz, K and Finnegan, A and Zhang, J and Glant, TT. (2002) T and B cell recovery in arthritis adoptively transferred to SCID mice: Antigen-specific activation is required for restoration of autopathogenic CD4+ Th1 cells in a syngeneic system J Immunol, 168, pp. 6013-6021.
7. Berlo, SE and Guichelaar, T and ten Brink, CB and Van Kooten, PJ and Hauet-Broere, F and Ludanyi, K and (2005) A proteoglycan (PG)-specific TCR transgenic mouse model of progressive polyarthritis Arthritis Rheum.
8. Adarichev, VA and Vermes, C and Hanyecz, A and Mikecz, K and Bremer, E and Glant, TT. (2005) Gene expression profiling in murine autoimmune arthritis during the initiation and progression of joint inflammation Arthritis Res Ther, 7, pp. R196-R207.
9. Hanyecz, A and Berlo, SE and Szanto, S and Broeren, CPM and Mikecz, K and Glant, TT. (2004) Achievement of a synergistic adjuvant effect on arthritis induction by activation of innate immunity and forcing the immune response toward the Th1 phenotype Arthritis Rheum, 50, pp. 1665-1676.
10. Glant, TT and Mikecz, K.(2004) Proteoglycan aggrecan-induced arthritis. A murine autoimmune model of rheumatoid arthritis. In Autoimmunity: methods and protocols. (pp. 313-338). Totowa, NJ: Humana Press.
11. Hanyecz, A and Bárdos, T and Berlo, SE and Buzás, E and Nesterovitch, AB and Mikecz, K and (2003) Induction of arthritis in SCID mice by T cells specific for the 'shared epitope' sequence in the G3 domain of human cartilage proteoglycan Arthritis Rheum, 48, pp. 2959-2973.
12. Sambrook, J and Fritsch, EF and Maniatis, T.(1989) Molecular cloning: A laboratory manual. New York: Cold Spring Harbor Laboratory Press.
13. Li, C and Wong, WH. (2001) Model-based analysis of oligonucleotide arrays: Expression index computation and outlier detection Proc Natl Acad Sci U S A, 98, pp. 31-36.
14. Ashburner, M and Ball, CA and Blake, JA and Botstein, D and Butler, H and Cherry, JM and (2000) Gene ontology: Tool for the unification of biology. The gene ontology consortium Nat Genet, 25, pp. 25-29.
15. Fantuzzi, L and Spadaro, F and Vallanti, G and Canini, I and Ramoni, C and Vicenzi, E and (2003) Endogenous CCL2 (monocyte chemotactic protein-1) modulates human immunodeficiency virus type-1 replication and affects cytoskeleton organization in human monocyte-derived macrophages Blood, 102, pp. 2334-2337.
16. Weber, C. (2003) Novel mechanistic concepts for the control of leukocyte transmigration: Specialization of integrins, chemokines, and junctional molecules J Mol Med, 81, pp. 4-19.
17. Menten, P and Saccani, A and Dillen, C and Wuyts, A and Struyf, S and Proost, P and (2002) Role of the autocrine chemokines MIP-1alpha and MIP-1beta in the metastatic behavior of murine T cell lymphoma J Leukoc Biol, 72, pp. 780-789.
18. Sallusto, F and Palermo, B and Lenig, D and Miettinen, M and Matikainen, S and Julkunen, I and (1999) Distinct patterns and kinetics of chemokine production regulate dendritic cell function Eur J Immunol, 29, pp. 1617-1625.
19. Vulcano, M and Albanesi, C and Stoppacciaro, A and Bagnati, R and D'Amico, G and Struyf, S and (2001) Dendritic cells as a major source of macrophage-derived chemokine/CCL22 in vitro and in vivo Eur J Immunol, 31, pp. 812-822.
20. Zhang, J and Bärdos, T and Mikecz, K and Finnegan, A and Glant, TT. (2001) Impaired Fas signaling pathway is involved in defective T cell apoptosis in autoimmune arthritis J Immunol, 166, pp. 4981-4986.
21. Neumann, E and Barnum, SR and Tarner, IH and Echols, J and Fleck, M and Judex, M and (2002) Local production of complement proteins in rheumatoid arthritis synovium Arthritis Rheum, 46, pp. 934-945.
22. Crockard, AD and Thompson, JM and McBride, SJ and Edgar, JD and McNeill, TA and Bell, AL. (1992) Markers of inflammatory activation: Upregulation of complement receptors CR1 and CR3 on synovial fluid neutrophils from patients with inflammatory joint disease Clin Immunol Immunopathol, 65, pp. 135-142.
23. Hietala, MA and Nandakumar, KS and Persson, L and Fahlen, S and Holmdahl, R and Pekna, M. (2004) Complement activation by both classical and alternative pathways is critical for the effector phase of arthritis Eur J Immunol, 34, pp. 1208-1216.