Evolution of thiazolidine-based blockers of human Kv1.5 for the treatment of atrial arrhythmias

Bioorganic and Medicinal Chemistry Letters

Volumn 17, Issue 1, 2007, Pages 282-284

  Jackson, Chris M ^a   Blass, Benjamin ^a   Coburn, Keith ^a   Djandjighian, Laurent ^a   Fadayel, Gina ^a   Fluxe, Andrew J ^a   Hodson, Steven J ^a   Janusz, John M ^a   Murawsky, Michael ^a   Ridgeway, James M ^a   White, Ronald E ^a   Wu, Shengde ^a  

^a PROCTER AND GAMBLE PHARMACEUTICALS   (United States)

Author keywords

Atrial fibrillation; Atrial selective; Human Kv1.5; Potassium channel; Thiazolidine

Indexed keywords

POTASSIUM CHANNEL BLOCKING AGENT; POTASSIUM CHANNEL KV1.5; THIAZOLIDINE DERIVATIVE;

ARTICLE; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; HEART ATRIUM ARRHYTHMIA; HEART ATRIUM FLUTTER; HUMAN;

ANIMALS; ANTI-ARRHYTHMIA AGENTS; ATRIAL FIBRILLATION; ATRIAL FLUTTER; HUMANS; KV1.5 POTASSIUM CHANNEL; POTASSIUM CHANNEL BLOCKERS; RATS; THIAZOLIDINES;

EID: 33845667257     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2006.07.007     Document Type: Article

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