Development of a semi-automated chemical stability system to analyze solution based formulations in support of discovery candidate selection

Journal of Pharmaceutical and Biomedical Analysis

Volumn 43, Issue 2, 2007, Pages 522-526

  Hitchingham, Linda ^a   Thomas, V Hayden ^a  

^a PFIZER INC   (United States)

Author keywords

Chemical stability; Discovery formulation; Generic analytical method; Pre clinical development; RP LC

Indexed keywords

REAGENT;

ACCURACY; ACIDITY; ALKALINITY; ANALYTIC METHOD; ARTICLE; CHEMICAL ANALYSIS; DRUG FORMULATION; DRUG SOLUTION; DRUG STABILITY; LABORATORY AUTOMATION; PHASE SEPARATION; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REVERSED PHASE LIQUID CHROMATOGRAPHY; SEPARATION TECHNIQUE; SPECTRAL SENSITIVITY; ULTRAVIOLET RADIATION; VALIDATION PROCESS;

AUTOANALYSIS; CHEMISTRY, PHARMACEUTICAL; CHROMATOGRAPHY, LIQUID; DRUG STABILITY; LINEAR MODELS; PHARMACEUTICAL PREPARATIONS; REPRODUCIBILITY OF RESULTS; SOLUTIONS; SOLVENTS; SPECTROPHOTOMETRY, ULTRAVIOLET; TECHNOLOGY, PHARMACEUTICAL; TIME FACTORS;

EID: 33845658781     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpba.2006.08.004     Document Type: Article

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