SV40 and human cancer: A review of recent data

International Journal of Cancer

Volumn 120, Issue 2, 2007, Pages 215-223

  Shah, Keerti V ^a  

^a JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

Human cancer; Mesothelioma; Polio vaccines; Simian virus 40 (SV40)

Indexed keywords

FORMALDEHYDE; POLIOMYELITIS VACCINE; VIRUS DNA; VIRUS T ANTIGEN;

BRAIN TUMOR; CANCER RISK; CARCINOGENESIS; CROSS REACTION; DNA SEQUENCE; HUMAN; IMMUNIZATION; IMMUNOREACTIVITY; INCIDENCE; MESOTHELIOMA; NONHODGKIN LYMPHOMA; NONHUMAN; OSTEOSARCOMA; PLASMID; POLYMERASE CHAIN REACTION; POLYOMA VIRUS; PREVALENCE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RHESUS MONKEY; SHORT SURVEY; SIMIAN VIRUS 40; VIRAL CONTAMINATION; VIRUS INFECTION;

ANTIBODIES, VIRAL; ANTIGENS, VIRAL; DNA, VIRAL; HUMANS; NEOPLASMS; SIMIAN VIRUS 40; VACCINATION;

EID: 33845648126     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.22425     Document Type: Short Survey

References (81)

1. Stratton K, Almario DA, McCormick MC. Immunization safety review: SV40 contamination of polio vaccine and cancer. Washington DC: National Academy Press, 2002.
2. Shah KV. Neutralizing antibodies to Simian virus 40 (SV40) in human sera from India. Proc Soc Exp Biol Med 1966;121:303-7.
3. Offit P. The Cutter incident. New Haven: Yale University Press, 2005.
4. Sweet BH, Hilleman MR. The vacuolatine virus. SV40. Proc Soc Exp Biol Med 1960;105:420-7.
5. Shah KV, Nathanson N. Human exposure to SV40: review and comment. Am J Epidemiol 1976;103:1-12.
6. Cutrone R, Lednicky J, Dunn G, Rizzo P, Bocchetta M, Chumakov K, Minor P, Carbone M. Some oral poliovirus vaccines were contaminated with infectious SV40 alter 1961. Cancer Res 2005;65:10273-9.
7. Sherwood RW, Buescher EL, Nitz RE, Cooch JW. Effects of adenovirus vaccine on acute respiratory disease in U.S. Army recruits. JAMA 1961;178:1125-7.
8. Fraumeni JF, Ederer F, Miller RW. An evaluation of the carcinogenicity of simian virus 40 in man. J Am Med Assoc 1963;185:713-18.
9. Vilchez RA, Butel JS. Emergent human pathogen simian virus 40 and its role in cancer. Clin Microbiol Rev 2004;17:495-508.
10. Garcea RL. Imperiale MJ. Simian virus 40 infection of humans. J Virol 2003;77:5039-45.
11. Gazdar AF, Butel JS, Carbone M. SV40 and human tumours: myth, association or causality? Nat Rev Cancer 2002;2:957-64.
12. Strickler HD. Simian virus 40 (SV40) and human cancers. Einstein Q J Biol Med 2001;18:14-20.
13. Barbanti-Brodano G, Sabbioni S, Martini F, Negrini M, Corallini A, Tognon M. BK virus, JC virus and simian virus 40 infection in humans, and association with human tumors. In: Ahsan N, ed. Polyomaviruses and human diseases. Georgetown, TX: Landes Bioscience, 2006;319-41.
14. Rollison DE. Epidemiological studies of polyomaviruses and cancer: previous findings, methodologic challenges and future directions. In: Ahsan N, ed. Polyomaviruses and human diseases. Georgetown, TX: Landes Bioscience, 2006;342-56.
15. Dang-Tan T, Mahmud SM, Puntoni R, Franco EL. Polio vaccines, Simian virus 40, and human cancer: the epidemiologic evidence for a causal association. Oncogcne 2004;23:6535-40.
16. Shah KV. Does SV40 infection contribute to the development of human cancers? Rev Med Virol 2000;10:31-43.
17. Engels EA. Does simian virus 40 cause non-Hodgkin lymphoma? A review of the laboratory and epidemiological evidence. Cancer Invest 2005;23:529-36.
18. Magnani C. SV40, genetic polymorphism and mesothelioma. Pathological and epidemiological evidence. Med Lav 2005;96:347-53.
19. Leithner A, Weinhaeusel A, Windhager R, Schlegl R, Waldner P, Lang S, Dominkus M, Zoubek A, Popper HH, Haas OA. Absence of SV40 in Austrian tumors correlates with low incidence of mesotheliomas. Cancer Biol Ther 2002;1:375-9.
20. Gordon GJ, Chen CJ, Jaklitsch MT, Richards WG, Sugarbaker DJ, Bueno R. Detection and quantification of SV40 large T-antigen DNA in mesothelioma tissues and cell lines. Oncol Rep 2002;9:631-4.
21. Hubner R, Van Marck E. Reappraisal of the strong association between simian virus 40 and human malignant mesothelioma of the pleura (Belgium). Cancer Causes Control 2002;13:121-9.
22. Mayull F, Barratt K, Shanks J. The detection of Simian virus 40 in mesotheliomas from New Zealand and England using real time FRET probe PCR protocols. J Clin Pathol 2003;56:728-30.
23. Lopez-Rios F, Illei PB, Rusch V, Ladanyi M. Evidence against a role for SV40 infection in human mesotheliomas and high risk of false-positive PCR results owing to presence of SV40 sequences in common laboratory plasmids. Lancet 2004;364:1157-66.
24. Jin M, Sawa H, Suzuki T, Shimizu K, Makino Y, Tanaka S, Nojima T, Fujioka Y, Asamoto M, Suko N, Fujila M, Nagashima K. Investigation of simian virus 40 large T antigen in 18 autopsied malignant mesothelioma patients in Japan. J Med Virol 2004;74:668-76.
25. Manfredi JJ, Dong J, Liu WJ, Resnick-Silverman L, Qiao R, Chahinian P, Saric M, Gibbs AR, Phillips JI, Murray J, Axien CW, Nolan RP, et al. Evidence against a role for SV40 in human mesothelioma. Cancer Res 2005;65:2602-9.
26. Brousset P, Sabatier J, Galateau-Salle F. SV40 infection in human cancers. Ann Oncol 2005;16:1212-13.
27. Aoe K, Hiraki A, Murakami T, Toyooka S, Shivapurkar N, Gazdar AF, Sueoka N, Taguchi K, Kamei T, Takeyama H, Sugi K, Kishimoto T. Infrequent existence of simian virus 40 large T antigen DNA in malignant mesothelioma in Japan. Cancer Sci 2006;97:292-5.
28. DeRienzo A, Tor M, Sterman DH, Aksoy F, Albelda SM, Testa JR. Detection of SV40 DNA sequences in malignant mesothelioma specimens from the United States, but not from Turkey. J Cell Biochem 2002;84:455-9.
29. Priftakis P, Bogdanovic G, Hjerpe A, Dalianis T. Presence of simian virus 40 (SV40) is not frequent in Swedish malignant mesotheliomas. Anticancer Res 2002;22:1357-60.
30. Cristaudo A, Foddis R, Vivaldi A, Buselli R, Gattini V, Guglielmi G, Cossentino F, Ottenga F, Ciancia E, Libener R, Filiberti R, Neri M, et al. SV40 enhances the risk of malignant mesothelioma among people exposed to asbestos: a molecular epidemiolonic case-control study. Cancer Res 2005;65:3049-52.
31. Kim JY, Koralnik U, LeFave M, Segal RA, Pfisler LA, Pomeroy SL. Medulloblastomas and primitive neuroectodermal tumors rarely contain polyomavirus DNA sequences. Neuro-oncology 2002;4:165-70.
32. Engels EA, Sarkar C, Daniel RW, Gravitt PE, Verma K, Quezado M, Shah KV. Absence of simian virus 40 in human brain tumors from northern India. Int J Cancer 2002;101:348-52.
33. Montesinos-Rongen M, Besleaga R, Heinsohn S, Sicbert R, Kabisch H, Wiestler OD, Deckert M. Absence of simian virus 40 DNA sequences in primary central nervous system lymphoma in HIV-negative patients. Virchows Arch 2004;444:436-8.
34. Rollison DEM, Utaipat U, Ryschkewitseh C, Hou J, Goldthwaite P, Daniel R, Helzlsouer KJ, Burger PC, Shah KV, Major EO. An investigation of human brain tumors for the presence of polyomavirus genome sequences by two independent laboratories. Int J Cancer 2005; 113:769-74.
35. Sabatier J, Uro-Coste E, Benouaich A, Boetto S, Gigaud M, Tremoulet M, Delisle MB, Galateau-Salle F, Brousset P. Immunodetection of SV40 large T antigen in human central nervous system tumours. J Clin Pathol 2005;58:429-31.
36. Martini F, Lazzarin L, Iaccheri L, Vignocchi B, Finocchiaro G, Magnani I, Serra M, Scotlandi K, Barbanti-Brodano G, Tognon M. Different simian virus 40 genomic regions and sequences homologous with SV40 large T antigen in DNA of human brain and bone tumors and of leukocytes from blood donors. Cancer 2002;94:1037-48.
37. Capello D, Rossi D, Gaudino G, Carbone A, Gaidano G. Simian virus 40 infection in lymphoproliferative disorders. Lancet 2003;361:88-9.
38. MacKenzie J, Wilson KS, Perry J, Gallagher A, Jarrett RF. Association between simian virus 40 DNA and lymphoma in the United Kingdom. J Natl Cancer Inst 2003;95:1001-3.
39. Daibata M, Nemoto Y, Kamioka M, Imai S, Taguchi H. Simian virus 40 in Japanese patients with lymphoproliferative disorders. Br J Haematol 2003;121:190-1.
40. Brousset P, deAraujo V, Gascoyne RD. Immunohistochemical investigation of SV40 large T antigen in Hodakin and non-Hodgkin's lymphoma. Int J Cancer 2004;112:533-5.
41. Sui LF, Williamson J, Lowenthal RM, Parker AJ, Absence of simian virus 40 (SV40) DNA in lymphoma samples from Tasmania. Australia. Pathology 2005;37:157-9.
42. Schuler F, Dolken SC, Hirt C, Dolken MT, Mentel R, Gurtler LG, Dolken G. No evidence for simian virus 40 DNA sequences in malignant non-Hodgkin lymphomas. Int J Cancer 2006;118:498-504.
43. Vilchez RA, Madden CR, Kozinetz CA, Halvorson SJ, White ZS, Jorgensen JL, Finch CJ, Butel JS. Association between simian virus 40 and non-Hodgkin lymphoma. Lancet 2002;359:817-23.
44. Shivapurkar N, Harada K, Reddy J, Scheuermann RH, Xu Y, McKenna RW, Milchgrub S, Kroft SH, Feng Z, Gazdar AF. Presence of simian virus 40 DNA sequences in human lymphomas. Lancet 2002; 359:851-2.
45. Nakatsuka S, Liu A, Dong Z, Nomura S, Takakuwa T, Miyazato H, Aozasa K. Simian virus 40 sequences in malignant lymphomas in Japan. Cancer Res 2003;63:7606-8.
46. Shivapurkar N, Takahashi T, Reddy J, Zheng Y, Stastny V, Collins R, Toyooka S, Suzuki M, Parikh G, Asplund S, Kroft SH, Timmons C, et al. Presence of simian virus 40 DNA sequences in human lymphoid and hematopoietic malignancies and their relationship to aberrant promoter methylation of multiple genes. Cancer Res 2004;64: 3757-60.
47. Meneses A, Lopez-Terrada D, Zanwar P, Killen DE, Monterroso V, Butel JS, Vilchez RA. Lymphoproliferative disorders in Costa Rica and simian virus 40. Haematologica 2005;90:1635-42.
48. Carbone M, Pass HI, Rizzo P, Marinetti M, Di Muzio M, Mew DJY, Levine AS, Procopio A. Simian virus 40-like sequences in human pleural mesothelioma. Oncogene 1994;9:1781-90.
49. Galateau-Salle F, Iwatsubo Y, Gennetay E, Renier A, Letourneux M, Pairon JC, Moritz S, Brochard P, Jaurand MD, Freymuth F. SV40-like DNA sequences in pleural mesothelioma, bronchopulmonary carcinoma, and non-malignant pulmonary diseases. J Pathol 1998;184: 252-7.
50. Volter C, zur Hausen H, Alber D, de Villters EM. A broad spectrum PCR method for the detection of polyomaviruses and avoidance of contamination by cloning vectors. Dev Biol Stand 1998;94:137-42.
51. Griffiths DJ, Nicholson AG, Weiss RA. Detection of SV40 sequences in human mesothelioma. Dev Biol Stand 1998;94:127-36.
52. Bergsagel DJ, Finegold MJ, Butel JS, Kupsky WJ, Garcea RL. DNA sequences similar to those of simian virus 40 in ependymomas and choroid plexus tumors of childhood. N Engl J Med 1992;326:988-93.
53. Martini F, Iaccheri L, Lazzarin L, Carinci P, Corallini A, Gerosa M, Iuzzolino P, Barbanti-Brodano G, Tognon M. SV40 early region and large T antigen in human brain tumors, peripheral blood cells, and sperm fluids from healthy individuals. Cancer Res 1996;56:4820-5.
54. Huang H, Reis R, Yonekawa Y, Lopes JM, Kleihues P, Ohgaki H. Identification in human brain tumors of DNA sequences specific for SV40 large T antigen. Brain Pathol 1999;9:33-44.
55. Arrington AS, Moore MS, Butel JS. SV40-positive brain tumor in scientist with risk of laboratory exposure to the virus. Oncogene 2004;23:2231-5.
56. Yazdi AS, Puchta U, Flaig MJ, Sander CA. Lack of evidence for the presence of Simian virus 40 DNA in cutaneous lymphomas. J Invest Dermmol 2003;121:212-13.
57. Ozdarendeli A, Camei C, Aygen E, Kirkil C, Toroman ZA, Dogru O, Doymaz MZ. SV40 in human thyroid nodules. J Clin Virol 2004; 30:337-40.
58. Wong NA, Rae F, Herriot MM, Mayer NJ, Brewster DH, Harrison DJ. SV40 tag DNA sequences, present in a small proportion of human hepatocellular carcinomas, are associated with reduced survival. J Clin Pathol 2003;56:904-9.
59. Martini F, Iaccheri L, Martinelli M, Martinello R, Grandi E, Mollica G, Tognon M. Papilloma and polyoma DNA tumor virus sequences in female genital tumors. Cancer Invest 2004;22:697-705.
60. Li RM, Branton MH, Tanawattanacharoen S, Falk RA, Jennettc JC, Kopp JB. Molecular identification of SV40 infection in human subjects and possible association with kidney disease. J Am Soc Nephrol 2002;13:2320-30.
61. Li RM, Mannon RB, Kleiner D, Tsokos M, Bynum M, Kirk AD, Kopp JB. BK virus and SV40 co-infection in polyomavirus nephropathy. Transplantation 2002;74:1497-1504.
62. Shah KV, Daniel RW, Strickler HD, Goedert JJ. Investigation of human urine for genomic sequences of the primate polyomaviruses simian virus 40. BK virus, and JC virus. J Infect Dis 1997;176:1618-21.
63. Galdenzi G, Lupo A, Anglani F, Perini M, Galeazzi L, Giunta S, Marcantoni C, Del Prete D, Graziatto R, D'Angelo A, Maschio G, Gambaro G. Is the simian virus SV40 associated with idiopathic focal segmental glomerulosclerosis in humans? J Nephrol 2003;16:350-6.
64. International SV40 Working Group. A multicenter evaluation of assays for detection of SV40 DNA and results in masked mesothelioma specimens. Cancer Epidemiol Biomarkers Prev 2001;10:523-32.
65. Shah KV, Galloway DA, Knowles WA, Viscidi RP. Simian virus 40 (SV40) and human cancer: a review of the serological data. Rev Med Virol 2004;14:1-9.
66. Viscidi RP, Rollison DE, Viscidi E, Clayman B, Rubalcaba E, Daniel R, Major EO, Shah KV. Serological cross-reactivities between antibodies to simian virus 40. BK virus, and JC virus assessed by virus-like-particle-based enzyme immunoassays. Clin Diagn Lab Immunol 2003;10:278-85.
67. Viscidi RP, Clayman B. Serological cross reactivity between polyomavirus capsids. In: Ahsan N. ed. Polyomaviruses and human diseases. Georgetown, TX: Landes Bioscience, 2006:73-84.
68. Knowles WA, Pipkin P, Andrews N, Vyse A, Minor P, Brown DWG, Miller E. Population-based study of antibody to the human polyomaviruses BKV and JCV and the simian polyomavirus SV40. J Med Virol 2003;71:115-23.
69. Carter JJ, Madeleine MM, Wipf GC, Garcea RL, Pipkin PA, Minor PD, Galloway DA. Lack of serological evidence for prevalent SV40 infection in humans. J Natl Cancer Inst 2003;95:1522-30.
70. Sanjose S, Shah KV, Domingo-Domenech E, Engels EA, Sevilla AF, Alvaro T, Garcia-Villanueva M, Romagosa V, Gonzalez-Barca E, Viscidi RP. Lack of serological evidence for an association between simian virus 40 and lymphoma. Int J Cancer 2003;104:522-4.
71. Strickler HD, Goedert JJ, Fleming M, Travis WD, Williams AE, Rabkin CS, Daniel RW, Shah KV. Simian virus 40 and pleural mesothelioma in humans. Cancer Epidemiol Biomarkers Prev 1996;5:473-5.
72. Rollison DE, Helzlsouer KJ, Alberg AJ, Hoffman S, Hou J, Daniel R, Shah KV, Major EO. Serum antibodies to JC virus, BK virus, simian virus 40, and the risk of incident adult astrocytic brain tumors. Cancer Epidemiol Biomarkers Prev 2003;12:460-3.
73. Rollison DE, Helzlsouer KJ, Halsey NA, Shah KV, Viscidi RP. Markers of past infection with simian virus 40 (SV40) and risk of incident non-Hodgkin lymphoma in a Maryland cohort. Cancer Epidemiol Biomarkers Prev 2005;14:1448-52.
74. Engels EA, Viscidi RP, Galloway DA, Carter JJ, Cerhan JR, Davis S. Cozen W, Severson RK, Sanjose S, Colt JH, Hartge P. Case-control study of simian virus 40 and non-Hodgkin lymphoma in the United States. J Natl Cancer Inst 2004;96:1368-74.
75. Engels EA, Chen J, Hartge P, Cerhan JR, Davis S, Severson RK, Cozen W, Viscidi RP. Antibody responses to simian virus 40 T antigen: a case-control study of non-Hodgkin lymphoma. Cancer Epidemiol Biomarkers Prev 2005;14:521-4.
76. Shah KV, Daniel RW, Murphy G. Antibodies reacting to Simian virus 40 T antigen in human sera. J Natl Cancer Inst 1973;51:687-90.
77. Rollison DE, Page WF, Crawford H, Gridley G, Wacholder S, Martin J, Miller R, Engels EA. Case-control study of cancer among US Army veterans exposed to simian virus 40-contaminated adenovirus vaccine. Am J Epidemiol 2004;160:317-24.
78. Engels EA, Katki HA, Nielsen NM, Whither JF, Hjalgrim H, Gjerris F, Rosenberg PS, Frisch M. Cancer incidence in Denmark following exposure to poliovirus vaccine contaminated with simian virus 40. J Natl Cancer Inst 2003;95:532-9.
79. Strickler HD, Goedert JJ, Devesa SS, Lahey J, Fraumeni JF, Jr, Rosenberg PS. Trends in U.S. pleural mesothelioma incidence rates following simian virus 40 contamination of early poliovirus vaccines. J Natl Cancer Inst 2003;95:38-45.
80. Thu GO, Hem LY, Hansen S, Moller B, Norstein J, Nokleby H, Grotmol T. Is there an association between SV40 contaminated polio vaccine and lymphoproliferative disorders? An age-period-cohort analysis on Norwegian data from 1953 to 1997. Int J Cancer 2006;118:2035-9.
81. Fisher SG, Weber L, Carbone M. Cancer risk associated with simian virus 40 contaminated polio vaccine. Anticancer Res 1999;19:2173-80.