Endothelin-converting enzyme-like peptidase 1

Handbook of Proteolytic Enzymes, Second Edition: Volume 1: Aspartic and Metallo Peptidases

Volumn 1, Issue , 2004, Pages 436-437

  Valdenaire, Olivier ^a  

^a Axovan Ltd   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 33845631000     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-0-12-079611-3.50120-8     Document Type: Chapter

References (7)

1. S. Kiryu-Seo, M. Sasaki, H. Yokohama, S. Nakagomi, T. Hirayama, S. Aoki, K. Wada and H. Kiyama (2000) Damage-induced neuronal endopeptidase (DINE) is a unique metallopeptidase expressed in response to neuronal damage and activates superoxide scavengers. Proc. Natl. Acad. Sci. USA 97 4345-4350.
2. A. Schweizer, O. Valdenaire, A. Köster, Y. Lang, G. Schmitt, B. Lenz, H. Blüthmann and J. Rohrer (1999) Neonatal lethality in mice deficient in XCE, a novel member of the endothelin-converting enzyme and neutral endopeptidase family. J. Biol. Chem. 274 20450-20456.
3. K. Shirotani, S. Tsubuki, N. Iwata, Y. Takaki, W. Harigaya, K. Maruyama, S. Kiryu-Seo, H. Kiyama, H. Iwata, T. Tomita, T. Iwatsubo and T.C. Saido (2001) Neprilysin degrades both amyloid beta peptides 1–40 and 1–42 most rapidly and efficiently among thiorphan- and phosphoramidon-sensitive endopeptidases. J. Biol. Chem. 276 21895-21901.
4. O. Valdenaire and A. Schweizer (2000) Endothelin-converting enzyme-like 1 (ECEL1; ‘XCE’): a putative metallopeptidase crucially involved in the nervous control of respiration. Biochem. Soc. Trans. 28 426-430.
5. O. Valdenaire, D. Lepailleur-Enouf, G. Egidy, A. Thouard, A. Barret, R. Vranckx, C. Tougard and J.B. Michel (1999) A fourth isoform of endothelin-converting enzyme (ECE-1) is generated from an additional promoter: molecular cloning and characterization. Eur. J. Biochem. 264 341-349.
6. O. Valdenaire, J.G. Richards, R.L.M. Faull and A. Schweizer (1999) XCE, a new member of the endothelin-converting enzyme and neutral endopeptidase family, is preferentially expressed in the CNS. Mol. Brain. Res. 64 211-221.
7. O. Valdenaire, E. Rohrbacher, A. Langeveld, A. Schweizer and C. Meijers (2000) Organization and chromosomal localization of the human ECEL1 (XCE) gene encoding a zinc metallopeptidase involved in the nervous control of respiration. Biochem. J. 346 611-616.