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Volumn 56, Issue SUPPL. 2, 2005, Pages 65-75

Age and hypertension related changes in genotypes of MTHFR 677C>T, 1298A>C and PON1 -108C>T SNPs in men with coronary artery disease (CAD)

Author keywords

Age; CAD; Case control study; Coronary artery disease; Homocysteine; Homocysteine thiolactone; Hypertension; MTHFR; Polymorphism; PON1; Retrospective study

Indexed keywords

ADULT; AGE; AGED; ALLELE; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY DISEASE; DISEASE ASSOCIATION; GENE; GENE EXPRESSION; GENETIC POLYMORPHISM; GENOTYPE; HUMAN; HYPERTENSION; MALE; MTHFR GENE; PON1 GENE; RISK ASSESSMENT; RISK FACTOR;

EID: 33845584536     PISSN: 08675910     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (6)

References (30)
  • 1
    • 0033121115 scopus 로고    scopus 로고
    • Synergistic effects of prothrombotic polymorphisms and atherogenic factors on the risk of myocardial infarction in young males
    • Inbal A, Freimark D, Modan B, et al. Synergistic effects of prothrombotic polymorphisms and atherogenic factors on the risk of myocardial infarction in young males. Blood 1999; 93: 2186-2190.
    • (1999) Blood , vol.93 , pp. 2186-2190
    • Inbal, A.1    Freimark, D.2    Modan, B.3
  • 2
    • 9144225352 scopus 로고    scopus 로고
    • Facts and recommendations about total homocysteine determinations: An expert opinion
    • Refsum H, Smith AD, Ueland PM, et al. Facts and recommendations about total homocysteine determinations: an expert opinion. Clin Chem 2004; 50: 3-32.
    • (2004) Clin Chem , vol.50 , pp. 3-32
    • Refsum, H.1    Smith, A.D.2    Ueland, P.M.3
  • 3
    • 0037657585 scopus 로고    scopus 로고
    • The interaction between MTHFR 677 C - >T genotype and folate status is a determinant of coronary atherosclerosis risk
    • Girelli D, Martinelli N, Pizzolo F, et al. The interaction between MTHFR 677 C - >T genotype and folate status is a determinant of coronary atherosclerosis risk. J Nutr 2003; 133: 1281-1285.
    • (2003) J Nutr , vol.133 , pp. 1281-1285
    • Girelli, D.1    Martinelli, N.2    Pizzolo, F.3
  • 4
    • 0029049553 scopus 로고
    • A candidate genetic risk factor for vascular disease: A common mutation in methylenetetrahydrofolate reductase
    • Frosst P, Blom H, Milos R, et al. A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase. Nature Genet 1995; 10: 111-113.
    • (1995) Nature Genet , vol.10 , pp. 111-113
    • Frosst, P.1    Blom, H.2    Milos, R.3
  • 5
    • 0031971515 scopus 로고    scopus 로고
    • A second mutation in the methylenetetrahydrofolate reductase gene: An additional risk factor for neural-tube defects?
    • Van Der Put N., Gabreels F., Stevens E., et al. A second mutation in the methylenetetrahydrofolate reductase gene: an additional risk factor for neural-tube defects? Am J Hum Genet 1998; 62: 1044-1051.
    • (1998) Am J Hum Genet , vol.62 , pp. 1044-1051
    • Van Der Put, N.1    Gabreels, F.2    Stevens, E.3
  • 7
    • 0042887610 scopus 로고    scopus 로고
    • Interrelationship between diabetes and homocysteine metabolism: Hormonal regulation of cystathionine beta-synthase
    • Schalinske KL. Interrelationship between diabetes and homocysteine metabolism: Hormonal regulation of cystathionine beta-synthase. Nutr Rev 2003; 61: 136-138.
    • (2003) Nutr Rev , vol.61 , pp. 136-138
    • Schalinske, K.L.1
  • 8
    • 11144244406 scopus 로고    scopus 로고
    • Hyperhomocysteinemia is inversely related with left ventricular ejection fraction and predicts cardiovascular mortality in high-risk coronary artery disease hypertensives
    • Cesari M, Zanchetta M, Burlina A, et al. Hyperhomocysteinemia is inversely related with left ventricular ejection fraction and predicts cardiovascular mortality in high-risk coronary artery disease hypertensives. Arlerioscler Thromb Vasc Biol 2005; 25: 115-121.
    • (2005) Arlerioscler Thromb Vasc Biol , vol.25 , pp. 115-121
    • Cesari, M.1    Zanchetta, M.2    Burlina, A.3
  • 9
    • 0034635449 scopus 로고    scopus 로고
    • Calcium-dependent human serum homocysteine thiolactone hydrolase. A protective mechanism against protein N-homocysteinylation
    • Jakubowski H. Calcium-dependent human serum homocysteine thiolactone hydrolase. A protective mechanism against protein N-homocysteinylation. J Biol Chem 2000; 275: 3957-3962.
    • (2000) J Biol Chem , vol.275 , pp. 3957-3962
    • Jakubowski, H.1
  • 10
    • 0032778517 scopus 로고    scopus 로고
    • Protein homocysteinylation: Possible mechanism underlying pathological consequences of elevated homocysteine levels
    • Jakubowski H. Protein homocysteinylation: possible mechanism underlying pathological consequences of elevated homocysteine levels. FASEB J 1999; 13: 2277-2283.
    • (1999) FASEB J , vol.13 , pp. 2277-2283
    • Jakubowski, H.1
  • 11
    • 0033973018 scopus 로고    scopus 로고
    • Promoter polymorphisms of human paraoxonase PON1 gene and serum paraoxonase activities and concentrations
    • Leviev I, James RW. Promoter polymorphisms of human paraoxonase PON1 gene and serum paraoxonase activities and concentrations. Arterioscler Thromb Vasc Biol 2000; 20: 516-521.
    • (2000) Arterioscler Thromb Vasc Biol , vol.20 , pp. 516-521
    • Leviev, I.1    James, R.W.2
  • 12
    • 84860038660 scopus 로고    scopus 로고
    • Among the males bearing the MTHFR 677T allele, the normotensive persons have the greater risk of abdominal aortic aneurysm (AAA) as compared to the hypertensive persons
    • Strauss E, Waliszewski K, Głuszek J, Pawlak AL. Among the males bearing the MTHFR 677T allele, the normotensive persons have the greater risk of abdominal aortic aneurysm (AAA) as compared to the hypertensive persons. Eur J Human Genet 2004; 12, suppl. 1: 298.
    • (2004) Eur J Human Genet , vol.12 , Issue.SUPPL. 1 , pp. 298
    • Strauss, E.1    Waliszewski, K.2    Głuszek, J.3    Pawlak, A.L.4
  • 13
    • 0035370968 scopus 로고    scopus 로고
    • Mutation A1298C of methylenetetrahydrofolate reductase: Risk for early coronary disease not associated with hyperhomocysteinemia
    • Szczeklik A, Sanak M, Jankowski M, et al. Mutation A1298C of methylenetetrahydrofolate reductase: risk for early coronary disease not associated with hyperhomocysteinemia. Am JMed Genet 2001; 101: 36-39.
    • (2001) Am J Med Genet , vol.101 , pp. 36-39
    • Szczeklik, A.1    Sanak, M.2    Jankowski, M.3
  • 14
    • 0031458361 scopus 로고    scopus 로고
    • The frequency of the methylenetetrahydrofolate reductase-gene mutation varies with age in the normal population
    • Matsushita S, Muramatsu T, Arai H, Matsui T, Higuchi S. The frequency of the methylenetetrahydrofolate reductase-gene mutation varies with age in the normal population. Am J Hum Genet 1997; 61: 1459-1460.
    • (1997) Am J Hum Genet , vol.61 , pp. 1459-1460
    • Matsushita, S.1    Muramatsu, T.2    Arai, H.3    Matsui, T.4    Higuchi, S.5
  • 16
    • 0035574446 scopus 로고    scopus 로고
    • Paraoxonase status in coronary heart disease: Are activity and concentration more important than genotype?
    • Mackness B, Davies GK, Turkie W, et al. Paraoxonase status in coronary heart disease: are activity and concentration more important than genotype? Arterioscler Thromb Vasc Biol 2001; 21: 1451-1457.
    • (2001) Arterioscler Thromb Vasc Biol , vol.21 , pp. 1451-1457
    • Mackness, B.1    Davies, G.K.2    Turkie, W.3
  • 17
    • 0036122850 scopus 로고    scopus 로고
    • High expressor paraoxonase PON1 gene promoter polymorphisms are associated with reduced risk of vascular disease in younger coronary patients
    • Leviev I, Poirier O, Nicaud V, et al. High expressor paraoxonase PON1 gene promoter polymorphisms are associated with reduced risk of vascular disease in younger coronary patients. Atherosclerosis 2002; 161: 463-467.
    • (2002) Atherosclerosis , vol.161 , pp. 463-467
    • Leviev, I.1    Poirier, O.2    Nicaud, V.3
  • 18
    • 18444377055 scopus 로고    scopus 로고
    • Genetic analysis of Paraoxonase (PON1) locus reveals an increased frequency of Arg192 allele in centenarians
    • Bonafe M, Marchegiani F, Cardelli M, et al. Genetic analysis of Paraoxonase (PON1) locus reveals an increased frequency of Arg192 allele in centenarians. Eur J Hum Genet 2002; 10: 292-296.
    • (2002) Eur J Hum Genet , vol.10 , pp. 292-296
    • Bonafe, M.1    Marchegiani, F.2    Cardelli, M.3
  • 19
    • 12144287437 scopus 로고    scopus 로고
    • Paraoxonase polymorphisms PON1 192 and 55 and longevity in Italian centenarians and Irish nonagenarians. A pooled analysis
    • Rea IM, McKeown PP, McMaster D, et al. Paraoxonase polymorphisms PON1 192 and 55 and longevity in Italian centenarians and Irish nonagenarians. A pooled analysis. Exp Gerontol 2004; 39: 629-635.
    • (2004) Exp Gerontol , vol.39 , pp. 629-635
    • Rea, I.M.1    McKeown, P.P.2    McMaster, D.3
  • 20
    • 3242687047 scopus 로고    scopus 로고
    • Association between serum paraoxonase (PON1) gene promoter T(-107)C polymorphism, PON1 activity and HDL levels in healthy Sicilian octogenarians
    • Campo S, Sardo MA, Trimarchi G, et al. Association between serum paraoxonase (PON1) gene promoter T(-107)C polymorphism, PON1 activity and HDL levels in healthy Sicilian octogenarians. Exp Gerontol 2004; 39: 1089-1094.
    • (2004) Exp Gerontol , vol.39 , pp. 1089-1094
    • Campo, S.1    Sardo, M.A.2    Trimarchi, G.3
  • 21
    • 3042766490 scopus 로고    scopus 로고
    • Clinical use and rational management of homocysteine, folic acid, and B vitamins in cardiovascular and thrombotic diseases
    • Stanger O, Herrmann W, Pietrzik K, et al. Clinical use and rational management of homocysteine, folic acid, and B vitamins in cardiovascular and thrombotic diseases. Z Kardiol 2004; 93: 439-453.
    • (2004) Z Kardiol , vol.93 , pp. 439-453
    • Stanger, O.1    Herrmann, W.2    Pietrzik, K.3
  • 22
    • 0029860742 scopus 로고    scopus 로고
    • Homocysteine-respondent genes in vascular endothelial cells identified by differential display analysis. GRP78/BiP and novel genes
    • Kokame K, Kato H, Miyata T. Homocysteine-respondent genes in vascular endothelial cells identified by differential display analysis. GRP78/BiP and novel genes. J Biol Chem 1996; 271: 29659-29665.
    • (1996) J Biol Chem , vol.271 , pp. 29659-29665
    • Kokame, K.1    Kato, H.2    Miyata, T.3
  • 23
    • 0035014266 scopus 로고    scopus 로고
    • Homocysteine-induced endoplasmic reticulum stress causes dysregulation of the cholesterol and triglyceride biosynthetic pathways
    • Werstuck GH, Lentz SR, Dayal S, et al. Homocysteine-induced endoplasmic reticulum stress causes dysregulation of the cholesterol and triglyceride biosynthetic pathways. J Clin Invest 2001; 107: 1263-1273.
    • (2001) J Clin Invest , vol.107 , pp. 1263-1273
    • Werstuck, G.H.1    Lentz, S.R.2    Dayal, S.3
  • 24
    • 0041989674 scopus 로고    scopus 로고
    • TDAG51 is induced by homocysteine, promotes detachment-mediated programmed cell death, and contributes to the development of atherosclerosis in hyperhomocysteinemia
    • Hossain GS, van Thienen JV, Werstuck GH, et al. TDAG51 is induced by homocysteine, promotes detachment-mediated programmed cell death, and contributes to the development of atherosclerosis in hyperhomocysteinemia. J Biol Chem 2003; 278: 30317-30327.
    • (2003) J Biol Chem , vol.278 , pp. 30317-30327
    • Hossain, G.S.1    Van Thienen, J.V.2    Werstuck, G.H.3
  • 25
    • 2542487367 scopus 로고    scopus 로고
    • Death Receptor Induced Apoptosis: A New Mechanism of Homocysteine- Mediated Endothelial Cell Cytotoxicity
    • Skurk C, Walsh K. Death Receptor Induced Apoptosis: A New Mechanism of Homocysteine-Mediated Endothelial Cell Cytotoxicity Hypertension 2004; 43: 1168-1170.
    • (2004) Hypertension , vol.43 , pp. 1168-1170
    • Skurk, C.1    Walsh, K.2
  • 26
    • 20044391979 scopus 로고    scopus 로고
    • Nitric Oxide Inhibition of Homocysteine-induced Human Endothelial Cell Apoptosis by Down-regulation of p53-dependent Noxa Expression through the Formation of S-Nitrosohomocysteine
    • Lee SJ, Kim KM, Namkoong S, et al. Nitric Oxide Inhibition of Homocysteine-induced Human Endothelial Cell Apoptosis by Down-regulation of p53-dependent Noxa Expression through the Formation of S-Nitrosohomocysteine. J Biol Chem 2005; 280: 5781-5788.
    • (2005) J Biol Chem , vol.280 , pp. 5781-5788
    • Lee, S.J.1    Kim, K.M.2    Namkoong, S.3
  • 27
    • 10344245574 scopus 로고    scopus 로고
    • NDRG1 Is Necessary for p53-dependent Apoptosis
    • Stein S., Thomas E. K., Herzog B., et al. NDRG1 Is Necessary for p53-dependent Apoptosis. J Biol Chem 2004; 279: 48930-48940.
    • (2004) J Biol Chem , vol.279 , pp. 48930-48940
    • Stein, S.1    Thomas, E.K.2    Herzog, B.3
  • 28
    • 0027531427 scopus 로고
    • Adverse vascular effects of homocysteine are modulated by endothelium-derived relaxing factor and related oxides of nitrogen
    • Stamler J.S., Osborne J.A., Jaraki O., et al. Adverse vascular effects of homocysteine are modulated by endothelium-derived relaxing factor and related oxides of nitrogen. J Clin Invest 1993; 91: 308-318.
    • (1993) J Clin Invest , vol.91 , pp. 308-318
    • Stamler, J.S.1    Osborne, J.A.2    Jaraki, O.3
  • 29
    • 0035109723 scopus 로고    scopus 로고
    • Elevation of asymmetrical dimethylarginine may mediate endothelial dysfunction during experimental hyperhomocyst(e)inaemia in humans
    • Boger RH, Lentz SR, Bode-Boger SM, Knapp HR, Haynes WG. Elevation of asymmetrical dimethylarginine may mediate endothelial dysfunction during experimental hyperhomocyst(e)inaemia in humans. Clin Sci (Lond) 2001; 100: 161-167.
    • (2001) Clin Sci (Lond) , vol.100 , pp. 161-167
    • Boger, R.H.1    Lentz, S.R.2    Bode-Boger, S.M.3    Knapp, H.R.4    Haynes, W.G.5
  • 30
    • 5644243210 scopus 로고    scopus 로고
    • Acute hyperhomocysteinemia decreases NO bioavailability in healthy adults
    • Romerio SC, Linder L, Nyfeler J, et al. Acute hyperhomocysteinemia decreases NO bioavailability in healthy adults. Atherosclerosis 2004; 176: 337-344.
    • (2004) Atherosclerosis , vol.176 , pp. 337-344
    • Romerio, S.C.1    Linder, L.2    Nyfeler, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.