The effect of water solubility of solutes on their flux through human skin in vitro

International Journal of Pharmaceutics

Volumn 329, Issue 1-2, 2007, Pages 25-36

  Majumdar, Susruta ^a   Thomas, Joshua ^a   Wasdo, Scott ^a   Sloan, Kenneth B ^a  

^a UNIVERSITY OF FLORIDA   (United States)

Author keywords

Flux; Human skin; In vitro; Lipid solubility; Water solubility

Indexed keywords

2 CHLOROPHENOL; 2 NAPHTHOL; 2,4 DICHLOROPHENOL; 2,4,6 TRICHLOROPHENOL; 3 NITROPHENOL; 3,4 XYLENOL; 4 BROMOPHENOL; 4 CHLOROPHENOL; 4 ETHYLPHENOL; 4 NITROPHENOL; ALKANOL; ANALGESIC AGENT; CARBOXYLIC ACID; CHLOROCRESOL; CHLOROXYLENOL; CODEINE; ESTRADIOL; FENTANYL; HYDROCORTISONE; HYDROMORPHONE; META CRESOL; METHYL PARABEN; OCTANOL; ORTHO CRESOL; PARA CRESOL; PHENOL; STEROID; THYMOL; UNINDEXED DRUG; WATER;

ARTICLE; CALCULATION; DATA BASE; DEPENDENT VARIABLE; DRUG PENETRATION; DRUG SOLUBILITY; EXPERIMENTAL STUDY; IN VITRO STUDY; INDEPENDENT VARIABLE; MATHEMATICAL MODEL; MOLECULAR WEIGHT; PHYSICAL CHEMISTRY; PREDICTION; PRIORITY JOURNAL; SKIN; SKIN ABSORPTION; SKIN PENETRATION; SKIN PERMEABILITY; SKINFOLD THICKNESS; SOLUTE; WATER PERMEABILITY;

ANALGESICS; FATTY ACIDS; FATTY ALCOHOLS; HUMANS; HYDROCORTISONE; ORGANIC CHEMICALS; PHENOLS; SKIN; SOLUBILITY; SOLUTIONS;

EID: 33845577021     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2006.08.015     Document Type: Article

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