Incidence of Down syndrome in Dubai, UAE

Medical Principles and Practice

Volumn 16, Issue 1, 2006, Pages 25-28

  Murthy, Sabita K ^a   Malhotra, Ashok K ^a   Mani, Sara ^a   Shara, Maryam Essa A ^a   Al Rowaished, Eman Essa Mohd ^a   Naveed, Sehba ^a   Alkhayat, Abdulla Ibrahim ^a   Alali, Mahmoud Taleb ^a  

^a Al Wasl Hospital   (United Arab Emirates)

Author keywords

Down syndrome; Down syndrome, incidence; Ethnicity; Maternal age; Middle East

Indexed keywords

ARTICLE; CHROMOSOME ANALYSIS; CHROMOSOME TRANSLOCATION; DOWN SYNDROME; DUBAI; FEMALE; GENETIC COUNSELING; GENETIC RISK; HUMAN; INCIDENCE; KARYOTYPING; MAJOR CLINICAL STUDY; MALE; MATERNAL AGE; MOSAICISM; NEWBORN; PARITY; PRENATAL DIAGNOSIS; RISK ASSESSMENT; RISK FACTOR; SYMPTOM; TRISOMY 21; UNITED ARAB EMIRATES;

ADOLESCENT; ADULT; DOWN SYNDROME; FEMALE; HUMANS; INCIDENCE; MALE; MATERNAL AGE; MIDDLE AGED; UNITED ARAB EMIRATES;

EID: 33845548364     PISSN: 10117571     EISSN: None     Source Type: Journal    
DOI: 10.1159/000096136     Document Type: Article

References (27)

1. Gardner RJM, Sutherland GR: Chromosome Abnormalities and Genetic Counseling, ed 3. Oxford, Oxford University Press, 2004.
2. Hecht CA, Hook EB: Rates of Down syndrome at live birth by one-year maternal age intervals in studies with apparent close to complete ascertainment in populations of European origin: a proposed rate schedule for use in genetic and prenatal screening. Am J Med Genet 1996;62:376-385.
3. Hsu LYF: Prenatal diagnosis of chromosomal abnormalities through amniocentesis; in Milunsky A (ed): Genetic Disorders and the Fetus, ed 4. Baltimore, Johns Hopkins University Press, 1998, pp 179-248.
4. Hassold T, Chiu D: Maternal age-specific rates of numerical chromosome abnormalities with special reference to trisomy. Hum Genet 1985;70:11-17.
5. Warburton D, Dallaire L, Thangavelu M, Ross L, Levin B, Kline J: Trisomy recurrence: a reconsideration based on North American data. Am J Hum Genet 2004;75:376-385.
6. Hassold T, Sherman S: Down syndrome: genetic recombination and origin of the extra chromosome 21. Clin Genet 2000;57:95-100.
7. Morton NE, Jacobs PA, Hassold T, Wu D: Maternal age in trisomy. Ann Hum Genet 1998;52:227-235.
8. Lamb NE, Yu K, Shaffer J, Feingold E, Sherman SL: Association between maternal age and meiotic recombination for trisomy 21. Am J Hum Genet 2005;76:91-99.
9. Farag TI, Al-Awadi SA, Al-Othman SA, Sundareshan TS, Krishna Murthy DS, Usha R, Mady SA, Uma R: Down syndrome and trisomy 18 in the Bedouins. Am J Med Genet 1988;29:943-944.
10. Al-Naggar RL, Mady SA, Tayel SM, Farag TI, Al-Awadi SA, Al-Ghanim MM, Abulhasan SJ, Sabry MA, Bastaki L: Profile of chromosomal abnormalities in the Al Jahara region of Kuwait. Med Princ Pract 1999;8:167-172.
11. Verma IC, Mathews AR, Faquih A, El-Zouki AA, Malik GR, Mohammed F: Cytogenetic analysis of Down syndrome in Libya. Indian J Pediatr 1990;57:245-248.
12. Harlap S: Down syndrome in West Jerusalem. Am J Epidemiol 1974;94:225-232.
13. Merrick J: Incidence and mortality of Down syndrome. Isr Med Assoc J 2000;2:25-26.
14. Abeliovich D, Atia Y, Sarov B: Down syndrome in Negev region. Am J Med Genet 1986;25:183.
15. Niazi MA, Al-Mazyad AS, Al-Husain MA, Al-Mofada SM, Al-Zamil FA, Khashoggi TY, Al-Eissa YA: Down syndrome in Saudi Arabia: incidence and cytogenetics. Hum Hered 1995;45:65-69.
16. Amir IM, Al-Tawila KA, Al-Harbi: Cytogenetics and prevalence of Down syndrome: a study from Saudi Arabia. Am J Hum Genet 2002;71(suppl): abstract 1204.
17. Wahab AA, Bener A, Teebi AS: The incidence patterns of Down syndrome in Qatar. Clin Genet 2006;69:360-362.
18. Zahed L, Megarbane A: A cytogenetic registry of Down syndrome in Lebanon. Commun Genet 1998;1:84-89.
19. Mokhtar MM, Abdel-Azziz AM, Nazmy NA, Mahrous HS: Cytogenetic profile of Down syndrome in Alexandria, Egypt. East Mediterr Health J 2003;9:37-44.
20. Seabright M: A rapid banding technique for human chromosomes. Lancet 1971;ii:971-972.
21. Clementi M, Bianca S, Benedicenti F, Tenconi R, Working Group on Down Syndrome: Down syndrome and parity. Commun Genet 1999;2:18-22.
22. Kallan K: Parity and Down syndrome. Am J Med Genet 1997;70:196-201.
23. Schimmel MS, Eidelman AI, Hammerman C, Kornbluth E, Zadka P: Increased parity and risk of trisomy 21: Review of 37,110 live births. BMJ 1997;314:720.
24. Chan A, McCaul KA, Keane RJ, Haan EA: Effect of parity, gravidity, previous miscarriage and age on risk of Down syndrome: population study. BMJ 1998;317:923-924.
25. Doria-Rose VP, Kim HS, Augustine ET, Edwards KL: Parity and the risk of Down's syndrome. Am J Epidemiol 2003;158:503-508.
26. Krishna Murthy DS, Farag TI: Recurrent regular trisomy-21 in two Bedouin families. Parental mosaicism versus genetic predisposition. Ann Genet 1995;38:217-224.
27. Carothers AD, Hecht CA, Hook EB: International variation in reported liveborth prevalence rates of Down syndrome, adjusted for maternal age. J Med Genet 1999;36:386-393.