Time-dependent transition from H2O2-extracellular signal-regulated kinase- to O2--nitric oxide-dependent mechanisms in the stimulatory effect of leptin on renal Na+/K +-ATPase in the rat

Clinical and Experimental Pharmacology and Physiology

Volumn 33, Issue 12, 2006, Pages 1216-1224

  Marciniak, Andrzej ^a   Borkowska, Ewelina ^a   Kȩdra, Anna ^a   Rychlik, Monika ^a   Beltowski, Jerzy ^a  

^a MEDICAL UNIVERSITY OF LUBLIN   (Poland)

Author keywords

Arterial hypertension; Hydrogen peroxide; Leptin; Mitogen activated protein kinases; Na+ K+ ATPase; Nitric oxide; Obesity; Superoxide anion radical

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 MORPHOLINO 8 PHENYLCHROMONE; 8 BROMO CYCLIC GMP; ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); ADENOSINE TRIPHOSPHATE; APOCYNIN; CATALASE; HYDROGEN PEROXIDE; LEPTIN; MITOGEN ACTIVATED PROTEIN KINASE; N BENZYL 2 CYANO 3 (3,4 DIHYDROXYPHENYL)ACRYLAMIDE; NITRIC OXIDE; OXYGEN; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; RECOMBINANT LEPTIN; TEMPOL; WORTMANNIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG ANTAGONISM; DRUG BLOOD LEVEL; DRUG EFFECT; DRUG MECHANISM; HYPERLEPTINEMIA; HYPERTENSION; KIDNEY PARENCHYMA; MALE; NONHUMAN; PROTEIN PHOSPHORYLATION; RAT; URINARY EXCRETION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ACETOPHENONES; ANIMALS; CYCLIC N-OXIDES; ENZYME INHIBITORS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FREE RADICAL SCAVENGERS; HYDROGEN PEROXIDE; INDICATORS AND REAGENTS; JANUS KINASES; KIDNEY; LEPTIN; MALE; NA(+)-K(+)-EXCHANGING ATPASE; NITRIC OXIDE; OXIDANTS; PHOSPHORYLATION; RATS; RATS, WISTAR; SPIN LABELS; STIMULATION, CHEMICAL; SUPEROXIDE DISMUTASE; SUPEROXIDES;

EID: 33845545281     PISSN: 03051870     EISSN: 14401681     Source Type: Journal    
DOI: 10.1111/j.1440-1681.2006.04513.x     Document Type: Article

References (49)

1. Pausova Z. From big fat cells to high blood pressure: A pathway to obesity-associated hypertension. Curr. Opin. Nephrol. Hypertens. 2006; 15: 173-8.
2. Haynes WG. Role of leptin in obesity-related hypertension. Exp. Physiol. 2005; 90: 683-8.
3. Beltowski J. Role of leptin in blood pressure regulation and arterial hypertension. J. Hypertens. 2006; 24: 789-801.
4. Considine RV, Sinha MK, Heiman ML et al. Serum immunoreactiveleptin concentrations in normal-weight and obese humans. N. Engl. J. Med. 1996; 334: 292-5.
5. Jackson EK, Li P. Human leptin has natriuretic activity in the rat. Am. J. Physiol. Renal Physiol. 1997; 272: F333-8.
6. Kuo JJ, Jones OB, Hall JE. Inhibition of NO synthesis enhances chronic cardiovascular and renal actions of leptin. Hypertension 2001; 37: 670-6.
7. Beltowski J, Wójcicka G, Marciniak A, Jamroz A. Oxidative stress, nitric oxide production, and renal sodium handling in leptin-induced hypertension. Life Sci. 2004; 74: 2987-3000.
8. El-Gharbawy AH, Kotchen JM, Grim CE et al. Gender-specific correlates of leptin with hypertension-related phenotypes in African Americans. Am. J. Hypertens. 2002; 15: 989-93.
9. Féraille E, Doucet A. Sodium-potassium-adenosinetriphosphatase- dependent sodium transport in the kidney: Hormonal control. Physiol. Rev. 2001; 81: 345-418.
10. +-ATPase trafficking in response to GPCR signals and intracellular sodium. Circ. Res. 2004; 95: 1100-8.
11. +-ATPase in proximal tubules in young spontaneously hypertensive rats. Hypertension 2004; 44: 95-100.
12. Banday AA, Hussain T, Lokhandwala MF. Renal dopamine D1 receptor dysfunction is acquired and not inherited in obese Zucker rats. Am. J. Physiol. Renal Physiol. 2004; 287: F109-16.
13. Tsuchida H, Imai G, Shima Y, Satoh T, Owada S. Mechanism of sodium load-induced hypertension in non-insulin dependent diabetes mellitus model rats: Defective dopaminergic system to inhibit Na-K-ATPase activity in renal epithelial cells. Hypertens. Res. 2001; 24: 127-35.
14. Bickel CA, Verbalis JG, Knepper MA, Ecelbarger CA. Increased renal Na-K-ATPase, NCC, and beta-ENaC abundance in obese Zucker rats. Am. J. Physiol. Renal Physiol. 2001; 281: F639-48.
15. +-ATPase in the proximal tubules of obese Zucker rats. Clin. Exp. Hypertens. 2006; 28: 29-40.
16. +-ATPase. The possible novel mechanism of leptin-induced hypertension. Pol. J. Pharmacol. 2004; 56: 213-22.
17. +-ATPase activity in hyperleptinemic rats. Pharmacol. Rep. 2005; 57: 219-28.
18. +-ATPase activity. Acta Biochim. Pol. 2005; 52: 803-9.
19. +-ATPase. Acta Biochim. Pol. 2004; 51: 933-42.
20. Hurst RO. The determination of nucleotide phosphorus with a stannous chloride-hydrazine sulphate reagent. Can. J. Biochem. 1964; 42: 287-92.
21. Lowry OH, Rosenbrough NI, Farr AL, Randall RJ. Protein measurement with the Folin phenol reagent. J. Biol. Chem. 1951; 193: 265-75.
22. Yuen JW, Benzie IF. Hydrogen peroxide in urine as a potential biomarker of whole body oxidative stress. Free Radic. Res. 2003; 37: 1209-13.
23. Paglia DE, Valentine WN. Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase. J. Lab Clin. Med. 1967; 70: 158-69.
24. Pham I, Sediame S, Maistre G et al. Renal and vascular effects of C-type and atrial natriuretic peptides in humans. Am. J. Physiol. Regul. Integr. Comp. Physiol. 1997; 273: R1457-64.
25. Guha PK, Villarreal D, Reams GP, Freeman RH. Role of leptin in the regulation of body fluid volume and pressures. Am. J. Ther. 2003; 10: 211-18.
26. Levy JR, Stevens W. Plasma hyperosmolality stimulates leptin secretion acutely by a vasopressin-adrenal mechanism. Am. J. Physiol. Endocrinol. Metab. 2004; 287: E263-8.
27. Villarreal D, Reams G, Freeman R, Spear R, Tchoukina I, Samar H. Leptin blockade attenuates sodium excretion in saline-loaded normotensive rats. Mol. Cell. Biochem. 2006; 283: 153-7.
28. +-ATPase activity in the rat: Impaired effect in dietary-induced obesity. Med. Sci. Monit. 2002; 8: BR221-9.
29. Villarreal D, Reams G, Freeman RH, Taraben A. Renal effects of leptin in normotensive, hypertensive, and obese rats. Am. J. Physiol. Regul. Integr. Comp. Physiol. 1998; 275: R2056-60.
30. Pal R, Sahu A. Leptin signaling in the hypothalamus during chronic central leptin infusion. Endocrinology 2003; 144: 3789-98.
31. Scarpace PJ, Matheny M, Zolotukhin S, Tumer N, Zhang Y. Leptin-induced leptin resistant rats exhibit enhanced responses to the melanocortin agonist MT II. Neuropharmacology 2003; 45: 211-19.
32. Munzberg H, Myers MG. Molecular and anatomical determinants of central leptin resistance. Nat. Neurosci. 2005; 8: 566-70.
33. Coatmellec-Taglioni G, Dausse JP, Giudicelli Y, Ribiere C. Sexual dimorphism in cafeteria diet-induced hypertension is associated with gender-related difference in renal leptin receptor down-regulation. J. Pharmacol. Exp. Ther. 2003; 305: 362-7.
34. Droge W. Free radicals in the physiological control of cell function. Physiol. Rev. 2002; 82: 47-95.
35. Zhan CD, Sindhu RK, Pang J, Ehdaie A, Vaziri ND. Superoxide dismutase, catalase and glutathione peroxidase in the spontaneously hypertensive rat kidney: Effect of antioxidant-rich diet. J. Hypertens. 2004; 22: 2025-33.
36. Meng S, Roberts LJ, Cason GW, Curry TS, Manning RD. Superoxide dismutase and oxidative stress in Dahl salt-sensitive and -resistant rats. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2002; 283: R732-8.
37. Kitiyakara C, Chabrashvili T, Chen Y et al. Salt intake, oxidative stress, and renal expression of NADPH oxidase and superoxide dismutase. J. Am. Soc. Nephrol. 2003; 14: 2775-82.
38. Chabrashvili T, Kitiyakara C, Blau J et al. Effects of ANG II type 1 and 2 receptors on oxidative stress, renal NADPH oxidase, and SOD expression. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2003; 285: R117-24.
39. Vaziri ND, Lin CY, Farmand F, Sindhu RK. Superoxide dismutase, catalase, glutathione peroxidase and NADPH oxidase in lead-induced hypertension. Kidney Int. 2003; 63: 186-94.
40. Farmand F, Ehdaie A, Roberts CK, Sindhu RK. Lead-induced dysregulation of superoxide dismutases, catalase, glutathione peroxidase, and guanylate cyclase. Environ. Res. 2005; 98: 33-9.
41. Sindhu RK, Roberts CK, Ehdaie A, Zhan CD, Vaziri ND. Effects of aortic coarctation on aortic antioxidant enzymes and NADPH oxidase protein expression. Life Sci. 2005; 76: 945-53.
42. Sainz J, Wangensteen R, Rodriguez GI et al. Antioxidant enzymes and effects of tempol on the development of hypertension induced by nitric oxide inhibition. Am. J. Hypertens. 2005; 18: 871-7.
43. Yu BP. Cellular defenses against damage from reactive oxygen species. Physiol. Rev. 1994; 74: 139-62.
44. Beltowski J, Marciniak A, Wójcicka G. Leptin decreases renal medullary Na(+),K(+)-ATPase activity through phosphatidylinositol 3-kinase dependent mechanism. J. Physiol. Pharmacol. 2004; 55: 391-407.
45. Kim J, Lee YR, Lee CH et al. Mitogen-activated protein kinase contributes to elevated basal tone in aortic smooth muscle from hypertensive rats. Eur. J. Pharmacol. 2005; 514: 209-15.
46. Olzinski AR, McCafferty TA, Zhao SQ et al. Hypertensive target organ damage is attenuated by a p38 MAPK inhibitor: Role of systemic blood pressure and endothelial protection. Cardiovasc. Res. 2005; 66: 170-8.
47. Xu ZG, Lanting L, Vaziri ND et al. Upregulation of angiotensin II type 1 receptor, inflammatory mediators, and enzymes of arachidonate metabolism in obese Zucker rat kidney: Reversal by angiotensin II type 1 receptor blockade. Circulation 2005; 111: 1962-9.
48. Srivastava T. Nondiabetic consequences of obesity on kidney. Pediatr. Nephrol. 2006; 21: 463-70.
49. Wolf G, Hamann A, Han DC et al. Leptin stimulates proliferation and TGF-beta expression in renal glomerular endothelial cells: Potential role in glomerulosclerosis. Kidney Int. 1999; 56: 860-72.