Sudden cardiac death in the young: A clinical genetic approach

Internal Medicine Journal

Volumn 37, Issue 1, 2007, Pages 32-37

  Ingles, J ^a,b   Semsarian, C ^a,b,c,d  

^a CENTENARY INSTITUTE   (Australia)

^b ROYAL PRINCE ALFRED HOSPITAL   (Australia)

^c University of Sydney   (Australia)

^d CENTENARY INSTITUTE   (Australia)

Author keywords

Family; Gene; Multidisciplinary; Screening; Sudden cardiac death

Indexed keywords

CARDIOLOGIST; CLINICAL FEATURE; CLINICAL GENETICS; FAMILY HISTORY; FAMILY RELATION; FORENSIC PATHOLOGY; GENETIC COUNSELING; GENETIC SCREENING; GENETICS; HEART DISEASE; HUMAN; HYPERTROPHIC CARDIOMYOPATHY; LONG QT SYNDROME; MULTIDISCIPLINARY CARE; PATIENT CARE; PRIORITY JOURNAL; PSYCHOLOGICAL ASPECT; REVIEW; SOCIAL ASPECT; SUDDEN DEATH;

ADOLESCENT; ADULT; AGE OF ONSET; ARRHYTHMIA; AUSTRALIA; CARDIOLOGY; CARDIOMYOPATHIES; CARDIOVASCULAR DISEASES; CAUSE OF DEATH; CHILD; CHILD, PRESCHOOL; COHORT STUDIES; DEATH, SUDDEN, CARDIAC; FAMILY HEALTH; FORENSIC PATHOLOGY; GENETIC COUNSELING; GENETIC PREDISPOSITION TO DISEASE; GENETICS, MEDICAL; HUMANS; INFANT; INTERDISCIPLINARY COMMUNICATION; MASS SCREENING; MEDICAL HISTORY TAKING; SOCIAL SUPPORT;

EID: 33845517423     PISSN: 14440903     EISSN: 14455994     Source Type: Journal    
DOI: 10.1111/j.1445-5994.2006.01241.x     Document Type: Review

References (14)

1. Zheng Z, Croft J, Giles W, Mensah G. Sudden cardiac death in the United States, 1989 to 1998. Circulation 2001; 104: 2158-63.
2. Tunstall-Pedoe H, Kuulasmaa K, Amouyel P, Arveiler D, Rajakangas AM, Pajak A. Myocardial infarction and coronary deaths in the World Health Organization MONICA Project. Registration procedures, event rates, and case-fatality rates in 38 populations from 21 countries in four continents. Circulation 1994; 90: 583-612.
3. Semsarian C, Maron BJ. Sudden cardiac death in the young. Med J Aust 2002; 176: 148-9.
4. Doolan A, Langlois N, Semsarian C. Causes of sudden cardiac death in young Australians. Med J Aust 2004; 180: 110-12.
5. Milewicz DM, Seidman CE. Genetics of cardiovascular disease. Circulation 2000; 102 (20 Suppl 4): IV103-111.
6. Ackerman MJ, Tester DJ, Driscoll DJ. Molecular autopsy of sudden unexplained death in the young. Am J Forensic Med Pathol 2001; 22: 105-111.
7. Tan HL, Hofman N, van Langen IM, van der Wal AC, Wilde AA. Sudden unexplained death: heritability and diagnostic yield of cardiological and genetic examination in surviving relatives. Circulation 2005; 112: 207-13.
8. Maron BJ, Seidman JG, Seidman CE. Proposal for contemporary screening strategies in families with hypertrophic cardiomyopathy. J Am Coll Cardiol 2004; 44: 2125-32.
9. Tsoutsman T, Lam L, Semsarian C. Genes, calcium and modifying factors in hypertrophic cardiomyopathy. Clin Exp Pharmacol Physiol 2006; 33: 139-45.
10. Tester DJ, Kopplin LJ, Will ML, Ackerman MJ. Spectrum and prevalence of cardiac ryanodine receptor (RyR2) mutations in a cohort of unrelated patients referred explicitly for long QT syndrome genetic testing. Heart Rhythm 2005; 2: 1099-105.
11. Ingles J, Doolan A, Chiu C, Seidman CE, Semsarian C. Compound and double mutations in patients with hypertrophic cardiomyopathy: implications for genetic testing and counselling. J Med Genet 2005; 42: e59.
12. Westenskow P, Splawski I, Timothy KW, Keating MT, Sanguinetti MC. Compound mutations: a common cause of severe long-QT syndrome. Circulation 2004; 109: 1834-41.
13. Merlevede E, Spooren D, Henderick H, Portzky G, Buylaert W, Jannes C et al. Perceptions, needs and mourning reactions of bereaved relatives confronted with a sudden unexpected death. Resuscitation 2004; 61: 341-8.
14. Parkes CM. Bereavement in adult life. BMJ 1998; 316: 856-9.