Molecular autopsy of sudden unexplained death in the young

American Journal of Forensic Medicine and Pathology

Volumn 22, Issue 2, 2001, Pages 105-111

  Ackerman, Michael J ^a,b   Tester, David J ^a,b   Driscoll, David J ^a,b  

^a MAYO CLINIC   (United States)

^b Mayo Eugenio Litta Children's Hospital   (United States)

Author keywords

Arrhythmia; Ion channels; Long QT syndrome; Molecular autopsy; Sudden unexplained death syndrome

Indexed keywords

ADRENALIN; CATECHOLAMINE;

ADOLESCENT; ARTICLE; AUTOPSY; BASE PAIRING; CASE REPORT; GENE AMPLIFICATION; GENE DELETION; HUMAN; HUMAN TISSUE; LONG QT SYNDROME; MALE; POTASSIUM CURRENT; SUDDEN DEATH;

ADOLESCENT; AUTOPSY; DEATH, SUDDEN, CARDIAC; DIAGNOSIS, DIFFERENTIAL; ELECTROCARDIOGRAPHY; EPINEPHRINE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; LONG QT SYNDROME; MALE; MUTATION; PEDIGREE;

EID: 0035019541     PISSN: 01957910     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000433-200106000-00001     Document Type: Article

References (23)

1. Sudden death from cardiac causes in children and young adults
2. Sudden unexpected death in children and adolescents
3. The investigation of sudden cardiac death
4. The long QT syndrome: A review of recent molecular genetic and physiologic discoveries
5. Ion channels: Basic science and clinical disease
6. The long QT syndrome: Ion channel diseases of the heart
7. Positional cloning of a novel, potassium channel gene: KVLQTl mutations cause cardiac arrhythmias
8. A molecular basis for cardiac arrhythmia: HERG mutations cause long QT syndrome
9. Molecular mechanisms for an inherited cardiac arrhythmia
10. Mapping of a gene for long QT syndrome to chromosome 4q25-27
11. Ks potassium channel
12. Spectrum of mutations in long-QT syndrome genes KVLQT1, HERG, SCN5A, KCNE1, and KCNE2
13. Talk to them
14. Use of cyclosporin A in establishing Epstein-Barr virus-transformed human lymphoblastoid cell lines
15. Genomic structure of three long QT syndrome genes: KVLQT1, HERG, and KCNE1
16. A novel mutation in KVLQT1 is the molecular basis of inherited long QT syndrome in a near drowning family
17. Molecular diagnosis of the inherited long QT syndrome in a woman who died after near-drowning
18. Swimming, a gene-specific arrhythmogenic trigger for inherited long QT syndrome
19. Diagnostic criteria for the long QT syndrome: An update
20. The spectrum of symptoms and QT intervals in carriers of the gene for the long-QT syndrome
21. Low penetrance in the long-QT syndrome: Clinical impact
22. The long QT syndrome: Ion channel diseases of the heart
23. Epinephrine-induced changes in serum potassium and cardiac repolarization and effects of pretreatment with propranolol and diltiazem