JC virus T′135, T′136 and T′165 proteins interact with cellular p107 and p130 in vivo and influence viral transformation potential

Journal of NeuroVirology

Volumn 12, Issue 6, 2006, Pages 428-442

  Bollag, Brigitte ^a   Kilpatrick, Lisa H ^a   Tyagarajan, Shiva K ^a   Tevethia, Mary J ^b   Frisque, Richard J ^a  

^a PENNSYLVANIA STATE UNIVERSITY   (United States)

^b PENN STATE COLLEGE OF MEDICINE   (United States)

Author keywords

Immortalization; JC virus; Phosphorylation; Rb proteins; T proteins; Transformation

Indexed keywords

GLYCINE CLEAVAGE SYSTEM; HEAT SHOCK COGNATE PROTEIN 70; PROTEIN P107; PROTEIN P130; PROTEIN T' 136; PROTEIN T' 165; PROTEIN T'135; RAS PROTEIN; REGULATOR PROTEIN; RETINOBLASTOMA PROTEIN; VIRUS ANTIGEN; VIRUS PROTEIN;

AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL AGING; CELL CLONING; CELL GROWTH; CELL IMMORTALIZATION; CELL LINE; CELL MUTANT; CONTROLLED STUDY; CYTOMEGALOVIRUS; EMBRYO; GENE AMPLIFICATION; GENE EXPRESSION; GENETIC CODE; GENETIC LINKAGE; IN VIVO STUDY; JC VIRUS; NONHUMAN; PHENOTYPE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; RAT; RETINOBLASTOMA; RNA SPLICING; SIMIAN VIRUS 40; VIRUS CELL INTERACTION; VIRUS CELL TRANSFORMATION; VIRUS TRANSCRIPTION; VIRUS TRANSFORMATION; WILD TYPE;

ALTERNATIVE SPLICING; ANIMALS; ANTIGENS, POLYOMAVIRUS TRANSFORMING; ANTIGENS, VIRAL, TUMOR; BLOTTING, WESTERN; CELL LINE; CELL TRANSFORMATION, VIRAL; JC VIRUS; RATS; RETINOBLASTOMA-LIKE PROTEIN P107; RETINOBLASTOMA-LIKE PROTEIN P130; VIRAL PROTEINS;

CYTOMEGALOVIRUS; JC POLYOMAVIRUS; POLYOMAVIRUS;

EID: 33845489472     PISSN: 13550284     EISSN: None     Source Type: Journal    
DOI: 10.1080/13550280601009553     Document Type: Article

References (44)

1. Ali, S and Kasper, J and Arai, T and DeCaprio, J. (2004) Cul7/p185/p193 binding to simian virus 40 large T antigen has a role in cellular transformation J Virol, 78, pp. 2749-2757. http://www4.infotrieve.com/ newmedline/detail.asp?NameID=14990695&Session=&searchQuery=J+ Virol%5BJournal+Name%5D+AND+78%5BVolume%5D+AND+2749%5BPage+Number%5D+AND+ 2004%5BPublication+Date%5D+AND+Ali%5BAuthor+Name%5D&count=1 http://www.csa.com/htbin/linkabst.cgi?issn=0022-538X&vol= 78&iss=&firstpage=2749
2. Beachy, T and Cole, S and Cavender, J and Tevethia, M. (2002) Regions and activities of simian virus 40 T antigen that cooperate with an activated ras oncogene in transforming primary rat embryo fibroblasts J Virol, 76, pp. 3145-3157. http://www4.infotrieve.com/newmedline/ detail.asp?NameID=11884539&Session=&searchQuery=J+Virol% 5BJournal+Name%5D+AND+76%5BVolume%5D+AND+3145%5BPage+Number%5D+AND+ 2002%5BPublication+Date%5D+AND+Beachy%5BAuthor+Name%5D&count=1 http://dx.doi.org/10.1128%2FJVI.76.7.3145-3157.2002 http://www.csa.com/ htbin/linkabst.cgi?issn=0022-538X&vol=76&iss=&firstpage=3145
3. Bollag, B and Chuke, W-F and Frisque, R. (1989) Hybrid genomes of the polyomaviruses JC virus, BK virus, and simian virus 40: Identification of sequences important for efficient transformation J Virol, 63, pp. 863-872. http://www4.infotrieve.com/newmedline/detail.asp?NameID= 2536108&Session=&searchQuery=J+Virol%5BJournal+Name%5D+AND+ 63%5BVolume%5D+AND+863%5BPage+Number%5D+AND+1989%5BPublication+Date%5D+ AND+Bollag%5BAuthor+Name%5D&count=1 http://www.csa.com/htbin/ linkabst.cgi?issn=0022-538X&vol=63&iss=&firstpage=863
4. Bollag, B and Prins, C and Snyder, E and Frisque, R. (2000) Purified JC virus T and T′ proteins differentially interact with the retinoblastoma family of tumor suppressor proteins Virology, 274, pp. 165-178. http://www4.infotrieve.com/newmedline/detail.asp?NameID= 10936097&Session=&searchQuery=Virology%5BJournal+Name%5D+AND+ 274%5BVolume%5D+AND+165%5BPage+Number%5D+AND+2000%5BPublication+Date%5D+ AND+Bollag%5BAuthor+Name%5D&count=1 http://dx.doi.org/ 10.1006%2Fviro.2000.0451 http://www.csa.com/htbin/ linkabst.cgi?issn=0042-6822&vol=274&iss=&firstpage=165
5. Boyapati, A and Wilson, M and Yu, J and Rundell, K. (2003) SV40 17KT antigen complements dnaJ mutations in large T antigen to restore transformation of primary human fibroblasts Virology, 315, pp. 148-158. http://www4.infotrieve.com/newmedline/detail.asp?NameID=14592767& Session=&searchQuery=Virology%5BJournal+Name%5D+AND+315%5BVolume%5D+ AND+148%5BPage+Number%5D+AND+2003%5BPublication+Date%5D+AND+Boyapati% 5BAuthor+Name%5D&count=1 http://dx.doi.org/10.1016%2FS0042- 6822%2803%2900524-5 http://www.csa.com/htbin/ linkabst.cgi?issn=0042-6822&vol=315&iss=&firstpage=148
6. Cavender, J and Conn, A and Epler, M and Lacko, H and Tevethia, M. (1995) Simian virus 40 T antigen contains two independent activities that cooperate with a ras oncogene to transform rat embryo fibroblasts J Virol, 69, pp. 923-934. http://www4.infotrieve.com/newmedline/ detail.asp?NameID=7815561&Session=&searchQuery=J+Virol%5BJournal+ Name%5D+AND+69%5BVolume%5D+AND+923%5BPage+Number%5D+AND+1995% 5BPublication+Date%5D+AND+Cavender%5BAuthor+Name%5D&count=1 http://www.csa.com/htbin/linkabst.cgi?issn=0022-538X&vol= 69&iss=&firstpage=923
7. DeCaprio, J and Ludlow, J and Figge, J and Shew, J and Huang, C and Lee, W and Marsilio, E and Paucha, E and Livingston, D. (1988) SV40 large tumor antigen forms a specific complex with the product of the retinoblastoma susceptibility gene Cell, 54, pp. 275-283. http://www4.infotrieve.com/newmedline/detail.asp?NameID=2839300& Session=&searchQuery=Cell%5BJournal+Name%5D+AND+54%5BVolume%5D+AND+ 275%5BPage+Number%5D+AND+1988%5BPublication+Date%5D+AND+DeCaprio% 5BAuthor+Name%5D&count=1 http://dx.doi.org/10.1016%2F0092- 8674%2888%2990559-4 http://www.csa.com/htbin/ linkabst.cgi?issn=0576-9787&vol=54&iss=&firstpage=275
8. Dyson, N and Howley, P and Munger, K and Harlow, E. (1989) The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product Science, 243, pp. 934-936. http://www4.infotrieve.com/ newmedline/detail.asp?NameID=2537532&Session=&searchQuery= Science%5BJournal+Name%5D+AND+243%5BVolume%5D+AND+934%5BPage+Number%5D+ AND+1989%5BPublication+Date%5D+AND+Dyson%5BAuthor+Name%5D&count=1 http://dx.doi.org/10.1126%2Fscience.2537532 http://www.csa.com/htbin/ linkabst.cgi?issn=0294-0337&vol=243&iss=&firstpage=934
9. Eash, S and Manley, K and Gasparovic, M and Querbes, W and Atwood, W. (2006) The human polyomaviruses Cell Mol Life Sci, 63, pp. 865-876. http://www4.infotrieve.com/newmedline/detail.asp?NameID=16501889& Session=&searchQuery=Cell+Mol+Life+Sci%5BJournal+Name%5D+AND+ 63%5BVolume%5D+AND+865%5BPage+Number%5D+AND+2006%5BPublication+ Date%5D+AND+Eash%5BAuthor+Name%5D&count=1 http://dx.doi.org/ 10.1007%2Fs00018-005-5454-z http://www.csa.com/htbin/ linkabst.cgi?issn=1420-682X&vol=63&iss=&firstpage=865
10. Fanning, E and Knippers, R. (1992) Structure and function of simian virus 40 large tumor antigen Ann Rev Biochem, 61, pp. 55-85. http://www4.infotrieve.com/newmedline/detail.asp?NameID=1323237& Session=&searchQuery=Ann+Rev+Biochem%5BJournal+Name%5D+AND+ 61%5BVolume%5D+AND+55%5BPage+Number%5D+AND+1992%5BPublication+ Date%5D+AND+Fanning%5BAuthor+Name%5D&count=1 http://dx.doi.org/ 10.1146%2Fannurev.bi.61.070192.000415 http://www.csa.com/htbin/ linkabst.cgi?issn=0066-4154&vol=61&iss=&firstpage=55
11. Frisque, R.(1983) Regulatory sequences and virus-cell interactions of JC virus. In Polyomaviruses and human neurological disease. (pp. 41-59). New York: Alan R. Liss.
12. Frisque, R and White, F, III. (1992) The molecular biology of JC virus, causative agent of progressive multifocal leukoencephalopathy. In Molecular neurovirology, (pp. 25-158). Totowa NJ: Humana Press.
13. Goldfarb, M and Shimizu, K and Perucho, M and Wigler, M. (1982) Isolation and preliminary characterization of a human transforming gene from T24 bladder carcinoma cells Nature, 296, pp. 404-409. http://www4.infotrieve.com/newmedline/detail.asp?NameID=7063039& Session=&searchQuery=Nature%5BJournal+Name%5D+AND+296%5BVolume%5D+ AND+404%5BPage+number%5D+AND+1982%5BPublication+Date%5D+AND+Goldfarb% 5BAuthor+Name%5D&count=1 http://dx.doi.org/10.1038%2F296404a0 http://www.csa.com/htbin/ linkabst.cgi?issn=0028-0887&vol=296&iss=&firstpage=404
14. Haggerty, S and Walker, D and Frisque, R. (1989) JC virus-simian virus 40 genomes containing heterologous regulatory signals and chimeric early regions: Identification of regions restricting transformation by JC virus J Virol, 63, pp. 2180-2190. http://www4.infotrieve.com/newmedline/ detail.asp?NameID=2539511&Session=&searchQuery=J+Virol%5BJournal+ Name%5D+AND+63%5BVolume%5D+AND+2180%5BPage+Number%5D+AND+ 1989%5BPublication+Date%5D+AND+Haggerty%5BAuthor+Name%5D&count=1 http://www.csa.com/htbin/linkabst.cgi?issn=0022-538X&vol= 63&iss=&firstpage=2180
15. Harris, K and Christensen, J and Radany, E and Imperiale, M. (1998) Novel mechanisms of E2F induction by BK virus large-T antigen: Requirement of both the pRb-binding and the J domains Mol Cell Biol, 18, pp. 1746-1756. http://www4.infotrieve.com/newmedline/detail.asp?NameID= 9488491&Session=&searchQuery=Mol+Cell+Biol%5BJournal+Name%5D+AND+ 18%5BVolume%5D+AND+1746%5BPage+Number%5D+AND+1998%5BPublication+Date%5D+ AND+Harris%5BAuthor+Name%5D&count=1 http://www.csa.com/ htbin/linkabst.cgi?issn=1522-4724&vol=18&iss=&firstpage=1746
16. Kalderon, D and Smith, A. (1984) In vitro mutagenesis of a putative DNA binding domain of SV40 large-T Virology, 139, pp. 109-137. http://www4.infotrieve.com/newmedline/detail.asp?NameID=6093377& Session=&searchQuery=Virology%5BJournal+Name%5D+AND+139%5BVolume%5D+ AND+109%5BPage+Number%5D+AND+1984%5BPublication+Date%5D+AND+Kalderon% 5BAuthor+Name%5D&count=1 http://dx.doi.org/10.1016%2F0042- 6822%2884%2990334-9 http://www.csa.com/htbin/ linkabst.cgi?issn=0042-6822&vol=139&iss=&firstpage=109
17. Kasper, J and Kuwabara, H and Arai, T and Ali, S and DeCaprio, J. (2005) Simian virus 40 large T antigen's association with the CUL7 SCF complex contributes to cellular transformation J Virol, 79, pp. 11685-11692. http://www4.infotrieve.com/newmedline/detail.asp?NameID=16140746& Session=&searchQuery=J+Virol%5BJournal+Name%5D+AND+79%5BVolume%5D+ AND+11685%5BPage+Number%5D+AND+2005%5BPublication+Date%5D+AND+Kasper% 5BAuthor+Name%5D&count=1 http://dx.doi.org/ 10.1128%2FJVI.79.18.11685-11692.2005 http://www.csa.com/htbin/ linkabst.cgi?issn=0022-538X&vol=79&iss=&firstpage=11685
18. Kohrman, D and Imperiale, M. (1992) Simian virus 40 large T antigen stably complexes with a 185-kilodalton host protein J Virol, 66, pp. 1752-1760. http://www4.infotrieve.com/newmedline/detail.asp?NameID= 1310776&Session=&searchQuery=J+Virol%5BJournal+Name%5D+AND+ 66%5BVolume%5D+AND+1752%5BPage+Number%5D+AND+1992%5BPublication+Date%5D+ AND+Kohrman%5BAuthor+Name%5D&count=1 http://www.csa.com/ htbin/linkabst.cgi?issn=0022-538X&vol=66&iss=&firstpage=1752
19. Lin, J and DeCaprio, J. (2003) SV40 large T antigen promotes dephosphorylation of p130 J Biol Chem, 278, pp. 46482-46487. http://www4.infotrieve.com/newmedline/detail.asp?NameID=12968030& Session=&searchQuery=J+Biol+Chem%5BJournal+Name%5D+AND+278% 5BVolume%5D+AND+46482%5BPage+Number%5D+AND+2003%5BPublication+Date%5D+ AND+Lin%5BAuthor+Name%5D&count=1 http://dx.doi.org/ 10.1074%2Fjbc.M307044200 http://www.csa.com/htbin/ linkabst.cgi?issn=0884-3996&vol=278&iss=&firstpage=46482
20. Lynch, K and Frisque, R. (1991) Factors contributing to the restricted DNA replicating activity of JC virus Virology, 180, pp. 306-317. http://www4.infotrieve.com/newmedline/detail.asp?NameID=1845827& Session=&searchQuery=Virology%5BJournal+Name%5D+AND+180%5BVolume%5D+ AND+306%5BPage+Number%5D+AND+1991%5BPublication+Date%5D+AND+ Lynch%5BAuthor+Name%5D&count=1 http://dx.doi.org/10.1016%2F0042- 6822%2891%2990035-A http://www.csa.com/htbin/ linkabst.cgi?issn=0042-6822&vol=180&iss=&firstpage=306
21. McVey, D and Brizuela, L and Mohr, I and Marshak, D and Gluzman, Y and Beach, D. (1989) Phosphorylation of large tumor antigen by cdc2 stimulates SV40 DNA replication Nature, 341, pp. 503-507. http://www4.infotrieve.com/newmedline/detail.asp?NameID=2552322& Session=&searchQuery=Nature%5BJournal+Name%5D+AND+341%5BVolume%5D+ AND+503%5BPage+Number%5D+AND+1989%5BPublication+Date%5D+AND+McVey% 5BAuthor+Name%5D&count=1 http://dx.doi.org/10.1038%2F341503a0 http://www.csa.com/htbin/ linkabst.cgi?issn=0028-0887&vol=341&iss=&firstpage=503
22. Niv, Y and Goel, A and Boland, C. (2005) JC virus and colorectal cancer: a possible trigger in the chromosomal instability pathways Curr Opin Gatroenterol, 21, pp. 85-89. http://www.csa.com/htbin/linkabst.cgi?issn= &vol=21&iss=&firstpage=85
23. Prins, C and Frisque, R. (2001) JC virus T′ proteins encoded by alternatively spliced early mRNAs enhance T antigen-mediated viral DNA replication in human cells J NeuroVirol, 7, pp. 250-264. http://www4.infotrieve.com/newmedline/detail.asp?NameID=11517399& Session=&searchQuery=J+NeuroVirol%5BJournal+Name%5D+AND+7%5BVolume% 5D+AND+250%5BPage+Number%5D+AND+2001%5BPublication+Date%5D+AND+Prins% 5BAuthor+Name%5D&count=1 http://dx.doi.org/ 10.1080%2F13550280152403290 http://www.csa.com/htbin/ linkabst.cgi?issn=1355-0284&vol=7&iss=&firstpage=250
24. Risser, R and Pollack, R. (1974) A nonselective analysis of SV40 transformation of mouse 3T3 cells Virology, 59, pp. 477-489. http://www4.infotrieve.com/newmedline/detail.asp?NameID=4364825& Session=&searchQuery=Virology%5BJournal+Name%5D+AND+59%5BVolume%5D+ AND+477%5BPage+Number%5D+AND+1974%5BPublication+Date%5D+AND+Risser% 5BAuthor+Name%5D&count=1 http://dx.doi.org/10.1016%2F0042- 6822%2874%2990457-7 http://www.csa.com/htbin/ linkabst.cgi?issn=0042-6822&vol=59&iss=&firstpage=477
25. Scheidtmann, K and Buck, M and Schneider, J and Kalderon, D and Fanning, E and Smith, A. (1991) Biochemical characterization of phosphorylation site mutants of simian virus 40 large T-antigen: Evidence for interaction between amino- and carboxy-terminal domains J Virol, 65, pp. 1479-1490. http://www4.infotrieve.com/newmedline/detail.asp?NameID= 1847465&Session=&searchQuery=J+Virol%5BJournal+Name%5D+AND+ 65%5BVolume%5D+AND+1479%5BPage+Number%5D+AND+1991%5BPublication+Date%5D+ AND+Scheidtmann%5BAuthor+Name%5D&count=1 http://www.csa.com/htbin/ linkabst.cgi?issn=0022-538X&vol=65&iss=&firstpage=1479
26. Schneider, J and Fanning, E. (1988) Mutations in the phosphorylation sites of simian virus 40 (SV40) T antigen alter its origin DNA-binding specificity for site I or II and affect SV40 DNA replication activity J Virol, 62, pp. 1598-1605. http://www4.infotrieve.com/newmedline/ detail.asp?NameID=3357207&Session=&searchQuery=J+Virol%5BJournal+ Name%5D+AND+62%5BVolume%5D+AND+1598%5BPage+Number%5D+AND+ 1988%5BPublication+Date%5D+AND+Schneider%5BAuthor+Name%5D&count=1 http://www.csa.com/htbin/linkabst.cgi?issn=0022-538X&vol= 62&iss=&firstpage=1598
27. Sheng, Q and Denis, D and Ratnofsky, M and Roberts, T and DeCaprio, J and Schaffhausen, B. (1997) The DnaJ domain of polyomavirus large T is required to regulate RB family tumor suppressor function J Virol, 71, pp. 9410-9416. http://www4.infotrieve.com/newmedline/detail.asp?NameID= 9371601&Session=&searchQuery=J+Virol%5BJournal+Name%5D+AND+ 71%5BVolume%5D+AND+9410%5BPage+Number%5D+AND+1997%5BPublication+Date%5D+ AND+Sheng%5BAuthor+Name%5D&count=1 http://www.csa.com/ htbin/linkabst.cgi?issn=0022-538X&vol=71&iss=&firstpage=9410
28. Stubdal, H and Zalvide, J and Campbell, K and Schweitzer, C and Roberts, T and DeCaprio, J. (1997) Inactivation of pRB-related proteins p130 and p107 mediated by the J domain of simian virus 40 large T antigen Mol Cell Biol, 17, pp. 4979-4990. http://www4.infotrieve.com/newmedline/ detail.asp?NameID=9271376&Session=&searchQuery=Mol+Cell+ Biol%5BJournal+Name%5D+AND+17%5BVolume%5D+AND+4979%5BPage+Number%5D+AND+ 1997%5BPublication+Date%5D+AND+Stubdal%5BAuthor+Name%5D&count=1 http://www.csa.com/htbin/linkabst.cgi?issn=1522-4724&vol= 17&iss=&firstpage=4979
29. Stubdal, H and Zalvide, J and DeCaprio, J. (1996) Simian virus 40 large T antigen alters the phosphorylation state of the RB-related proteins p130 and p107 J Virol, 70, pp. 2781-2788. http://www4.infotrieve.com/ newmedline/detail.asp?NameID=8627752&Session=&searchQuery=J+ Virol%5BJournal+Name%5D+AND+70%5BVolume%5D+AND+2781%5BPage+Number%5D+AND+ 1996%5BPublication+Date%5D+AND+Stubdal%5BAuthor+Name%5D&count=1 http://www.csa.com/htbin/linkabst.cgi?issn=0022-538X&vol= 70&iss=&firstpage=2781
30. Sullivan, C and Cantalupo, P and Pipas, J. (2000) The molecular chaperone activity of simian virus 40 large T antigen is required to disrupt Rb-E2F family complexes by an ATP-dependent mechanism Mol Cell Biol, 20, pp. 6233-6243. http://www4.infotrieve.com/newmedline/ detail.asp?NameID=10938100&Session=&searchQuery=Mol+Cell+ Biol%5BJournal+Name%5D+AND+20%5BVolume%5D+AND+6233%5BPage+Number%5D+AND+ 2000%5BPublication+Date%5D+AND+Sullivan%5BAuthor+Name%5D&count=1 http://dx.doi.org/10.1128%2FMCB.20.17.6233-6243.2000 http://www.csa.com/ htbin/linkabst.cgi?issn=1522-4724&vol=20&iss=&firstpage=6233
31. Sullivan, C and Gilbert, S and Pipas, J. (2001) ATP-dependent simian virus 40 T-antigen-Hsc70 complex formation J Virol, 75, pp. 1601-1610. http://www4.infotrieve.com/newmedline/detail.asp?NameID=11160658& Session=&searchQuery=J+Virol%5BJournal+Name%5D+AND+75%5BVolume%5D+ AND+1601%5BPage+Number%5D+AND+2001%5BPublication+Date%5D+AND+Sullivan% 5BAuthor+Name%5D&count=1 http://dx.doi.org/ 10.1128%2FJVI.75.4.1601-1610.2001 http://www.csa.com/ htbin/linkabst.cgi?issn=0022-538X&vol=75&iss=&firstpage=1601
32. Sullivan, C and Pipas, J. (2002) T antigens of simian virus 40: molecular chaperones for viral replication and tumorigenesis Micro Mol Biol Rev, 66, pp. 179-202. http://dx.doi.org/ 10.1128%2FMMBR.66.2.179-202.2002 http://www.csa.com/htbin/ linkabst.cgi?issn=1092-2172&vol=66&iss=&firstpage=179
33. Swenson, J and Frisque, R. (1995) Biochemical characterization and localization of JC virus large T antigen phosphorylation domains Virology, 212, pp. 295-308. http://www4.infotrieve.com/newmedline/ detail.asp?NameID=7571399&Session=&searchQuery=Virology% 5BJournal+Name%5D+AND+212%5BVolume%5D+AND+295%5BPage+Number%5D+AND+ 1995%5BPublication+Date%5D+AND+Swenson%5BAuthor+Name%5D&count=1 http://dx.doi.org/10.1006%2Fviro.1995W1487 http:/www.csa.com/htbin/ linkabst.cgi?issn=0042-6822&vol=212&iss=&firstpage=295
34. Tavis, J and Trowbridge, P and Frisque, R. (1994) Converting the JCV T antigen Rb binding domain to that of SV40 does not alter JCV's limited transforming activity but does eliminate viral viability Virology, 199, pp. 384-392. http://www4.infotrieve.com/newmedline/detail.asp?NameID= 8122368&Session=&searchQuery=Virology%5BJournal+Name%5D+AND+ 199%5BVolume%5D+AND+384%5BPage+Number%5D+AND+1994%5BPublication+Date%5D+ AND+Tavis%5BAuthor+Name%5D&count=1 http://dx.doi.org/ 10.1006%2Fviro.1994.1136 http://www.csa.com/htbin/ linkabst.cgi?issn=0042-6822&vol=199&iss=&firstpage=384
35. Tevethia, S and Epler, M and Georgoff, I and Teresky, A and Marlow, M and Levine, A. (1992) Antibody response to human papovavirus JC (JCV) and simian virus-40 (SV40) T-antigens in SV40 T antigen-transgenic mice Virology, 190, pp. 459-464. http://www4.infotrieve.com/newmedline/ detail.asp?NameID=1382342&Session=&searchQuery=Virology% 5BJournal+Name%5D+AND+190%5BVolume%5D+AND+459%5BPage+Number%5D+AND+ 1992%5BPublication+Date%5D+AND+Tevethia%5BAuthor+Name%5D&count=1 http://dx.doi.org/10.1016%2F0042-6822%2892%2991234-L http://www.csa.com/ htbin/linkabst.cgi?issn=0042-6822&vol=190&iss=&firstpage=459
36. Trowbridge, P and Frisque, R. (1993) Analysis of G418-selected Rat2 cells containing prototype, variant, mutant, and chimeric JC-virus and SV40 genomes Virology, 196, pp. 458-474. http://www4.infotrieve.com/ newmedline/detail.asp?NameID=8396798&Session=&searchQuery= Virology%5BJournal+Name%5D+AND+196%5BVolume%5D+AND+458%5BPage+Number%5D+ AND+1993%5BPublication+Date%5D+AND+Trowbridge%5BAuthor+ Name%5D&count=1 http://dx.doi.org/10.1006%2Fviro.1993.1502 http://www.csa.com/htbin/linkabst.cgi?issn=0042-6822&vol=196&iss= &firstpage=458
37. Trowbridge, P and Frisque, R. (1995) Identification of three new JC virus proteins generated by alternative splicing of the early viral mRNA J NeuroVirol, 1, pp. 195-206. http://www4.infotrieve.com/newmedline/ detail.asp?NameID=9222358&Session=&searchQuery=J+NeuroVirol% 5BJournal+Name%5D+AND+1%5BVolume%5D+AND+195%5BPage+Number%5D+AND+1995% 5BPublication+Date%5D+AND+Trowbridge%5BAuthor+Name%5D&count=1 http://www.csa.com/htbin/linkabst.cgi?issn=1355-0284&vol= 1&iss=&firstpage=195
38. Tyagarajan, S and Frisque, R. (2006) Stability and function of JC virus large T antigen and T′ proteins are altered by mutation of their phosphorylated threonine 125 residues J Virol, 80, pp. 2083-2091. http://www4.infotrieve.com/newmedline/detail.asp?NameID=16474116& Session=&searchQuery=J+Virol%5BJournal+Name%5D+AND+80%5BVolume%5D+ AND+2083%5BPage+Number%5D+AND+2006%5BPublication+Date%5D+AND+Tyagarajan% 5BAuthor+Name%5D&count=1 http://dx.doi.org/ 10.1128%2FJVI.80.5.2083-2091.2006 http://www.csa.com/ htbin/linkabst.cgi?issn=0022-538X&vol=80&iss=&firstpage=2083
39. Young, A and Longmore, G. (2004) Differential regulation of apoptotic genes by Rb in human versus mouse cells Oncogene, 23, pp. 2587-2599. http://www4.infotrieve.com/newmedline/detail.asp?NameID=15048095& Session=&searchQuery=Oncogene%5BJournal+Name%5D+AND+23%5BVolume%5D+ AND+2587%5BPage+Number%5D+AND+2004%5BPublication+Date%5D+AND+Young% 5BAuthor+Name%5D&count=1 http://dx.doi.org/10.1038%2Fsj.onc.1207330 http://www.csa.com/htbin/ linkabst.cgi?issn=0950-9232&vol=23&iss=&firstpage=2587
40. White, M and Khalili, K. (2005) Expression of JC virus regulatory proteins in human cancer: Potential mechanisms for tumourigenesis Eur J Cancer, 41, pp. 2537-2548. http://www4.infotrieve.com/newmedline/ detail.asp?NameID=16219459&Session=&searchQuery=Eur+J+ Cancer%5BJournal+Name%5D+AND+41%5BVolume%5D+AND+2537%5BPage+Number%5D+ AND+2005%5BPublication+Date%5D+AND+White%5BAuthor+Name%5D&count=1 http://dx.doi.org/10.1016%2Fj.ejca.2005.08.019 http://www.csa.com/htbin/linkabst.cgi?issn=0277-5379&vol=41&iss= &firstpage=2537
41. Whyte, P and Buchkovich, K and Horowitz, J and Friend, S and Raybuck, M and Weinberg, R and Harlow, E. (1988) Association between an oncogene and an antioncogene: The adenovirus E1A proteins bind to the retinoblastoma gene product Nature, 334, pp. 124-129. http://www4.infotrieve.com/newmedline/detail.asp?NameID=2968522& Session=&searchQuery=Nature%5BJournal+Name%5D+AND+334%5BVolume%5D+ AND+124%5BPage+Number%5D+AND+1988%5BPublication+Date%5D+AND+Whyte% 5BAuthor+Name%5D&count=1 http://dx.doi.org/10.1038%2F334124a0 http://www.csa.com/htbin/ linkabst.cgi?issn=0028-0887&vol=334&iss=&firstpage=124
42. Zalvide, J and Stubdal, H and Decaprio, J. (1998) The J domain of simian virus 40 large T antigen is required to functionally inactivate RB family proteins Mol Cell Biol, 18, pp. 1408-1415. http://www4.infotrieve.com/newmedline/detail.asp?NameID=9488456& Session=&searchQuery=Mol+Cell+Biol%5BJournal+Name%5D+AND+18% 5BVolume%5D+AND+1408%5BPage+Number%5D+AND+1998%5BPublication+Date%5D+ AND+Zalvide%5BAuthor+Name%5D&count=1 http://www.csa.com/htbin/ linkabst.cgi?issn=1522-4724&vol=18&iss=&firstpage=1408
43. Zerrahn, J and Knippschild, U and Winkler, T and Deppert, W. (1993) Independent expression of the transforming amino-terminal domain of SV40 large T-antigen from an alternatively spliced third SV40 early messenger RNA EMBO J, 12, pp. 4739-4746. http://www4.infotrieve.com/newmedline/ detail.asp?NameID=8223482&Session=&searchQuery=EMBO+J%5BJournal+ Name%5D+AND+12%5BVolume%5D+AND+4739%5BPage+Number%5D+AND+ 1993%5BPublication+Date%5D+AND+Zerrahn%5BAuthor+Name%5D&count=1 http://www.csa.com/htbin/linkabst.cgi?issn=0261-4189&vol= 12&iss=&firstpage=4739
44. Zhu, J and Rice, P and Gorsch, L and Abate, M and Cole, C. (1992) Transformation of a continuous rat embryo fibroblast cell line requires 3 separate domains of simian virus-40 large T-antigen J Virol, 66, pp. 2780-2791. http://www4.infotrieve.com/newmedline/detail.asp?NameID= 1313902&Session=&searchQuery=J+Virol%5BJournal+Name%5D+AND+ 66%5BVolume%5D+AND+2780%5BPage+Number%5D+AND+1992%5BPublication+Date%5D+ AND+Zhu%5BAuthor+Name%5D&count=1 http://www.csa.com/ htbin/linkabst.cgi?issn=0022-538X&vol=66&iss=&firstpage=2780