Elevation of Serum Krebs von den Lunge-6 Levels in Patients With Tubulointerstitial Nephritis and Uveitis Syndrome

American Journal of Kidney Diseases

Volumn 48, Issue 6, 2006, Pages 935-941

  Kase, Satoru ^a   Kitaichi, Nobuyoshi ^a   Namba, Kenichi ^a   Miyazaki, Akiko ^a   Yoshida, Kazuhiko ^a   Ishikura, Kenji ^a   Ikeda, Masahiro ^a   Nakashima, Taiji ^a   Ohno, Shigeaki ^a  

^a HOKKAIDO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

2 microglobulin; interstitial nephritis; Krebs von den Lunge 6; uveitis

Indexed keywords

BETA 2 MICROGLOBULIN; BETAMETHASONE; CORTICOSTEROID; GLYCOPROTEIN; KREBS VON DEN LUNGE 6; PREDNISOLONE;

ADOLESCENT; ADULT; ARTICLE; BLOOD SAMPLING; CHEMOLUMINESCENCE; CHILD; CONTROLLED STUDY; DIAGNOSTIC APPROACH ROUTE; ELECTROCHEMICAL DETECTION; FEMALE; FOLLOW UP; HUMAN; IMMUNOASSAY; IMMUNOREACTIVITY; INTERSTITIAL NEPHRITIS; KIDNEY BIOPSY; KIDNEY DISTAL TUBULE; KIDNEY PARENCHYMA; MAJOR CLINICAL STUDY; MALE; PROTEIN BLOOD LEVEL; PROTEIN DETERMINATION; STAINING; TISSUE FIXATION; TISSUE SECTION; UVEITIS;

ADOLESCENT; ADULT; ANTIGENS, NEOPLASM; BETA 2-MICROGLOBULIN; BIOLOGICAL MARKERS; CHILD; COMORBIDITY; FEMALE; HUMANS; IMMUNOASSAY; IMMUNOHISTOCHEMISTRY; MALE; MUCINS; NEPHRITIS, INTERSTITIAL; SYNDROME; UVEITIS;

EID: 33845449533     PISSN: 02726386     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.ajkd.2006.09.013     Document Type: Article

References (29)

1. Vanhaesebrouck P., Carton D., De Bel C., et al. Acute tubulo-interstitial nephritis and uveitis syndrome (TINU syndrome). Nephron 40 (1985) 418-422
2. Mandeville J.T., Levinson R.D., and Holland G.N. The tubulointerstitial nephritis and uveitis syndrome. Surv Ophthalmol 46 (2001) 195-208
3. Salu P., Stempels N., Vanden Houte K., et al. Acute tubulointerstitial nephritis and uveitis syndrome in the elderly. Br J Ophthalmol 74 (1990) 53-55
4. Rosenbaum J.T. Bilateral anterior uveitis and interstitial nephritis. Am J Ophthalmol 105 (1988) 534-537
5. Tanaka H., Suzuki K., Nakahata T., et al. Repeat renal biopsy in a girl with tubulointerstitial nephritis and uveitis syndrome. Pediatr Nephrol 16 (2001) 885-887
6. Deguchi H.E., and Amemiya T. Two cases of uveitis with tubulointerstitial nephritis in HTLV-1 carriers. Jpn J Ophthalmol 47 (2003) 372-378
7. Takemura T., Okada M., Hino S., et al. Course and outcome of tubulointerstitial nephritis and uveitis syndrome. Am J Kidney Dis 34 (1999) 1016-1021
8. Kikkawa Y., Mimura A., and Inage Z. [Regional distribution of sulfatide in human kidney, and anti-sulfatide antibodies in sera from patients with nephritis detected by TLC immunostaining]. Nippon Jinzo Gakkai Shi 33 (1991) 635-642
9. Wakaki H., Sakamoto H., and Awazu M. Tubulointerstitial nephritis and uveitis syndrome with autoantibody directed to renal tubular cells. Pediatrics 107 (2001) 1443-1446
10. Kohno N., Akiyama M., Kyoizumi S., et al. Detection of soluble tumor-associated antigens in sera and effusions using novel monoclonal antibodies, KL-3 and KL-6, against lung adenocarcinoma. Jpn J Clin Oncol 18 (1988) 203-216
11. Kohno N., Kyoizumi S., Awaya Y., et al. New serum indicator of interstitial pneumonitis activity. Sialylated carbohydrate antigen KL-6. Chest 96 (1989) 68-73
12. Hayashi Y., Kao W.W., Kohno N., et al. Expression patterns of sialylated epitope recognized by KL-6 monoclonal antibody in ocular surface epithelium of normals and dry eye patients. Invest Ophthalmol Vis Sci 45 (2004) 2212-2217
13. Kobayashi J., and Kitamura S. KL-6: A serum marker for interstitial pneumonia. Chest 108 (1995) 311-315
14. Hamada H., Kohno N., Akiyama M., et al. Monitoring of serum KL-6 antigen in a patient with radiation pneumonia. Chest 101 (1992) 858-860
15. Tokiya R., Hiratsuka J., Yoshida K., et al. Evaluation of serum KL-6 as a predictive marker of radiation pneumonitis in patients with breast-conservation therapy. Int J Clin Oncol 9 (2004) 498-502
16. Hamada H., Kohno N., Yokoyama A., et al. KL-6 as a serologic indicator of Pneumocystis carinii pneumonia in immunocompromised hosts. Intern Med 37 (1998) 307-310
17. Narita M., Tanaka H., Abe S., et al. Close association between pulmonary disease manifestation in Mycoplasma pneumoniae infection and enhanced local production of interleukin-18 in the lung, independent of gamma interferon. Clin Diagn Lab Immunol 7 (2000) 909-914
18. Kobayashi J., and Kitamura S. Serum KL-6 for the evaluation of active pneumonitis in pulmonary sarcoidosis. Chest 109 (1996) 1276-1282
19. Ogawa Y., Ishikawa T., Ikeda K., et al. Evaluation of serum KL-6, a mucin-like glycoprotein, as a tumor marker for breast cancer. Clin Cancer Res 6 (2000) 4069-4072
20. Kohno N., Kyoizumi S., Tanabe M., et al. Detection of a circulating tumor-associated antigen with a murine monoclonal antibody, LISA 101, selected by reversed indirect enzyme-linked immunosorbent assay. Cancer Res 49 (1989) 3412-3419
21. Kitaichi N., Ariga T., Kase S., et al. Usefulness of quantifying serum KL-6 levels in the follow-up of uveitic patients with sarcoidosis. Graefes Arch Clin Exp Ophthalmol 244 (2006) 433-437
22. Kitaichi N., Kotake S., Shibuya H., et al. Increase of KL-6 in sera of uveitis patients with sarcoidosis. Graefes Arch Clin Exp Ophthalmol 241 (2003) 879-883
23. Takahashi T., Takamura K., Sakaue S., et al. Elevated serum KL-6 concentrations in patients with diabetes mellitus. J Diabetes Complications 16 (2002) 352-358
24. Goda C., Kotake S., Ichiishi A., et al. Clinical features in tubulointerstitial nephritis and uveitis (TINU) syndrome. Am J Ophthalmol 140 (2005) 637-641
25. Kikkawa Y., Sakurai M., Mano T., et al. Interstitial nephritis with concomitant uveitis. Report of two cases. Contrib Nephrol 4 (1975) 1-11
26. Azar R., Verove C., and Boldron A. Delayed onset of uveitis in TINU syndrome. J Nephrol 13 (2000) 381-383
27. Kase S., Kitaichi N., Furudate N., et al. Increased expression of mucinous glycoprotein KL-6 in human pterygium. Br J Ophthalmol 90 (2006) 1208-1209
28. Eiro M., Katoh T., and Watanabe T. Risk factors for bleeding complications in percutaneous renal biopsy. Clin Exp Nephrol 9 (2005) 40-45
29. Parrish A.E. Complications of percutaneous renal biopsy: A review of 37 years' experience. Clin Nephrol 38 (1992) 135-141