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Volumn 45, Issue 12, 2006, Pages 1177-1188

Pharmacokinetic profile of dexloxiglumide

Author keywords

[No Author keywords available]

Indexed keywords

17 DEACETYL NORGESTIMATE; CIMETIDINE; CYTOCHROME P450 2C9; CYTOCHROME P450 3A4; DEXLOXIGLUMIDE; DEXLOXIGLUMIDE CARBOXYLIC ACID; DICLOFENAC; ETHINYLESTRADIOL; ETHINYLESTRADIOL PLUS NORGESTIMATE; FLUCONAZOLE; KETOCONAZOLE; NORGESTIMATE; O DEMETHYL DEXLOXIGLUMIDE;

EID: 33845438851     PISSN: 03125963     EISSN: 03125963     Source Type: Journal    
DOI: 10.2165/00003088-200645120-00003     Document Type: Review
Times cited : (10)

References (20)
  • 2
    • 33646724266 scopus 로고    scopus 로고
    • CCK1 antagonists: Are they ready for clinical use?
    • Shajan AS, D'Amato M, Beglinger C. CCK1 antagonists: are they ready for clinical use? Dig Dis 2006; 24: 1-13
    • (2006) Dig Dis , vol.24 , pp. 1-13
    • Shajan, A.S.1    D'Amato, M.2    Beglinger, C.3
  • 3
    • 10744233931 scopus 로고    scopus 로고
    • Absorption, distribution, metabolism and excretion of the cholecystokinin-1 antagonist dexloxiglumide in the rat
    • Webber C, Stokes CA, Persiani S, et al. Absorption, distribution, metabolism and excretion of the cholecystokinin-1 antagonist dexloxiglumide in the rat. Eur J Drug Metab Pharmacokinet 2003; 28 (3): 201-12
    • (2003) Eur J Drug Metab Pharmacokinet , vol.28 , Issue.3 , pp. 201-212
    • Webber, C.1    Stokes, C.A.2    Persiani, S.3
  • 4
    • 2442549723 scopus 로고    scopus 로고
    • Absorption, distribution, metabolism and excretion of the cholecystokinin-1 antagonist dexloxiglumide in the dog
    • Webber C, Stokes CA, Persiani S, et al. Absorption, distribution, metabolism and excretion of the cholecystokinin-1 antagonist dexloxiglumide in the dog. Eur J Drug Metab Pharmacokinet 2004; 29 (1): 15-23
    • (2004) Eur J Drug Metab Pharmacokinet , vol.29 , Issue.1 , pp. 15-23
    • Webber, C.1    Stokes, C.A.2    Persiani, S.3
  • 6
    • 0005490955 scopus 로고    scopus 로고
    • The CCK1 receptor antagonist dexloxiglumide is effective and safe in female patients with constipation predominant irritable bowel syndrome
    • [abstract]
    • D'Amato M, Whorwell PJ, Thomson DG, et al. The CCK1 receptor antagonist dexloxiglumide is effective and safe in female patients with constipation predominant irritable bowel syndrome [abstract]. Am J Gastroenterol 2001; 96: S31
    • (2001) Am J Gastroenterol , vol.96
    • D'Amato, M.1    Whorwell, P.J.2    Thomson, D.G.3
  • 7
    • 0037464611 scopus 로고    scopus 로고
    • Development and validation of a bioanalytical method for the determination of the cholecystokinin type-1 (CCK1) receptor antagonist dexloxiglumide in human plasma
    • Brodie R, Peard A, Roth A, et al. Development and validation of a bioanalytical method for the determination of the cholecystokinin type-1 (CCK1) receptor antagonist dexloxiglumide in human plasma. J Chromatogr B 2003; 784: 91-100
    • (2003) J Chromatogr B , vol.784 , pp. 91-100
    • Brodie, R.1    Peard, A.2    Roth, A.3
  • 8
    • 27444441686 scopus 로고    scopus 로고
    • Effect of azole antifungals ketoconazole and fluconazole on the pharmacokinetics of dexloxiglumide
    • Jakate AS, Roy P, Patel A, et al. Effect of azole antifungals ketoconazole and fluconazole on the pharmacokinetics of dexloxiglumide. Br J Clin Pharmacol 2005; 60 (5): 498-507
    • (2005) Br J Clin Pharmacol , vol.60 , Issue.5 , pp. 498-507
    • Jakate, A.S.1    Roy, P.2    Patel, A.3
  • 9
    • 10744222974 scopus 로고    scopus 로고
    • Pharmacokinetics and metabolism of the cholecystokinin antagonist dexloxiglumide in male human subjects
    • Webber C, Roth A, Persiani S, et al. Pharmacokinetics and metabolism of the cholecystokinin antagonist dexloxiglumide in male human subjects. Xenobiotica 2003; 33 (6): 625-41
    • (2003) Xenobiotica , vol.33 , Issue.6 , pp. 625-641
    • Webber, C.1    Roth, A.2    Persiani, S.3
  • 10
    • 0141507964 scopus 로고    scopus 로고
    • Characterization of dexloxiglumide in vitro biopharmaceutical properties and active transport
    • Tolle-Sander S, Grill A, Joshi H, et al. Characterization of dexloxiglumide in vitro biopharmaceutical properties and active transport. J Pharm Sci 2003; 92 (10): 1968-80
    • (2003) J Pharm Sci , vol.92 , Issue.10 , pp. 1968-1980
    • Tolle-Sander, S.1    Grill, A.2    Joshi, H.3
  • 11
    • 0036251597 scopus 로고    scopus 로고
    • Pharmacokinetics of dexloxiglumide after administration of single and repeated oral escalating doses in healthy young males
    • Persiani S, D'Amato M, Makovec F, et al. Pharmacokinetics of dexloxiglumide after administration of single and repeated oral escalating doses in healthy young males. Int J Clin Pharmacol Ther 2002; 40 (5): 198-206
    • (2002) Int J Clin Pharmacol Ther , vol.40 , Issue.5 , pp. 198-206
    • Persiani, S.1    D'Amato, M.2    Makovec, F.3
  • 12
    • 33845437242 scopus 로고    scopus 로고
    • Evaluation of intestinal absorption sites for dexloxiglumide, a novel selective cholecystokinin (CCK1) receptor antagonist, in healthy subjects
    • [abstract]. Nov 7-11; Baltimore (MD)
    • Roy P, Jakate A, Niamehr S, et al. Evaluation of intestinal absorption sites for dexloxiglumide, a novel selective cholecystokinin (CCK1) receptor antagonist, in healthy subjects [abstract]. 2004 AAPS Annual Meeting and Exposition; 2005 Nov 7-11; Baltimore (MD)
    • (2005) 2004 AAPS Annual Meeting and Exposition
    • Roy, P.1    Jakate, A.2    Niamehr, S.3
  • 13
    • 33845429214 scopus 로고    scopus 로고
    • Effect of a high fat meal on the bioavailability of dexloxiglumide from tablet in healthy subjects
    • [abstract]. Oct 26-30; Salt Lake City (UT)
    • Roy P, Nolting A, Abramowitz W, et al. Effect of a high fat meal on the bioavailability of dexloxiglumide from tablet in healthy subjects [abstract]. 2003 AAPS Annual Meeting and Exposition; 2003 Oct 26-30; Salt Lake City (UT)
    • (2003) 2003 AAPS Annual Meeting and Exposition
    • Roy, P.1    Nolting, A.2    Abramowitz, W.3
  • 16
    • 2942637496 scopus 로고    scopus 로고
    • Interaction of dexloxiglumide, a cholecystokinin type-1 receptor antagonist, with human cytochromes P450
    • Hall M, Persiani S, Cheung Y-L, et al. Interaction of dexloxiglumide, a cholecystokinin type-1 receptor antagonist, with human cytochromes P450. Biopharm Drug Dispos 2004; 25: 163-76
    • (2004) Biopharm Drug Dispos , vol.25 , pp. 163-176
    • Hall, M.1    Persiani, S.2    Cheung, Y.-L.3
  • 18
    • 24944554604 scopus 로고    scopus 로고
    • The single-dose pharmacokinetics of the novel CCK1 receptor antagonist, dexloxiglumide, are not influenced by age and gender
    • Roy P, Wangsa J, Patel A, et al. The single-dose pharmacokinetics of the novel CCK1 receptor antagonist, dexloxiglumide, are not influenced by age and gender. Int J Clin Pharmacol Ther 2005; 43 (9): 444-51
    • (2005) Int J Clin Pharmacol Ther , vol.43 , Issue.9 , pp. 444-451
    • Roy, P.1    Wangsa, J.2    Patel, A.3
  • 20
    • 16844370522 scopus 로고    scopus 로고
    • Effect of multiple-dose dexloxiglumide on the pharmacokinetics of oral contraceptives in healthy women
    • Roy P, Jakate AS, Patel A, et al. Effect of multiple-dose dexloxiglumide on the pharmacokinetics of oral contraceptives in healthy women. J Clin Pharmacol 2005; 45: 329-36
    • (2005) J Clin Pharmacol , vol.45 , pp. 329-336
    • Roy, P.1    Jakate, A.S.2    Patel, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.