Synthetic applications of Baylis-Hillman chemistry: An efficient and solely stereoselective synthesis of (E)-α-methylcinnamic acids and potent hypolipidemic agent LK-903 from unmodified Baylis-Hillman adducts

Chemical and Pharmaceutical Bulletin

Volumn 54, Issue 12, 2006, Pages 1725-1727

  Das, Biswanath ^a   Banerjee, Joydeep ^a   Chowdhury, Nikhil ^a   Majhi, Anjoy ^a  

^a INDIAN INSTITUTE OF CHEMICAL TECHNOLOGY   (India)

Author keywords

(E) methylcinnamic acid; Baylis Hillman adduct; Hypolipidemic agent; LK 903; Stereoselective synthesis

Indexed keywords

ALPHA METHYLCINNAMIC ACID DERIVATIVE; ANTILIPEMIC AGENT; METHYL 3 HYDROXY 3 ARYL 2 METHYLENEPROPANOATE DERIVATIVE; PROPIONIC ACID DERIVATIVE; REAGENT;

ARTICLE; BAYLIS HILLMAN REACTION; DRUG POTENCY; DRUG SYNTHESIS; HYDROLYSIS; ROOM TEMPERATURE; STEREOCHEMISTRY;

ANTILIPEMIC AGENTS; CINNAMATES; GLYCERIDES; MOLECULAR STRUCTURE;

EID: 33845407223     PISSN: 00092363     EISSN: 13475223     Source Type: Journal    
DOI: 10.1248/cpb.54.1725     Document Type: Article

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