Bone morphogenetic protein 2 induced differentiation toward superficial epithelial cells in the gastric mucosa

Journal of Gastroenterology

Volumn 41, Issue 11, 2006, Pages 1064-1075

  Itoh, Keisuke ^a   Kataoka, Hiromi ^a   Sasaki, Makoto ^a   Tanida, Satoshi ^a   Oshima, Tadayuki ^a   Ogasawara, Naotaka ^a   Ohara, Hirotaka ^a   Nakao, Haruhisa ^a   Joh, Takashi ^a  

^a NAGOYA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICAL SCIENCES   (Japan)

Author keywords

BMP2; Epithelial mesenchymal interaction; MUC5AC

Indexed keywords

COLLAGEN GEL; MESSENGER RNA; MORPHOGEN; MUCIN 5AC; NOGGIN; PROTEIN KINASE B; RECOMBINANT BONE MORPHOGENETIC PROTEIN 2; SMAD1 PROTEIN;

ANIMAL CELL; ARTICLE; BRANCHING MORPHOGENESIS; CELL CULTURE; CELL DIFFERENTIATION; CELL INTERACTION; CELL PROLIFERATION; CELL STRAIN 3T3; COCULTURE; CONTROLLED STUDY; EPITHELIUM CELL; GENE EXPRESSION; GENE EXPRESSION REGULATION; IMMUNOFLUORESCENCE; IN VITRO STUDY; MOUSE; MOUSE STRAIN; MYOFIBROBLAST; NONHUMAN; NUCLEOTIDE SEQUENCE; PHASE CONTRAST MICROSCOPY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STOMACH EPITHELIUM; STOMACH MUCOSA; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; BONE MORPHOGENETIC PROTEINS; CELL DIFFERENTIATION; CELL LINE; EPITHELIAL CELLS; FIBROBLASTS; FLUORESCENT ANTIBODY TECHNIQUE; GASTRIC MUCOSA; GENE EXPRESSION; MICE; MICE, INBRED BALB C; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TRANSFORMING GROWTH FACTOR BETA;

EID: 33845404154     PISSN: 09441174     EISSN: 14355922     Source Type: Journal    
DOI: 10.1007/s00535-006-1899-6     Document Type: Article

References (39)

1. SM Karam CP Leblond 1993 Dynamics of epithelial cells in the corpus of the mouse stomach. I. Identification of proliferative cell types and pinpointing of the stem cell Anat Rec 236 259-79 10.1002/ar.1092360202 1:STN:280:ByyA3s3isVM%3D 8338232
2. K Haffen M Kedinger P Simon-Assmann 1987 Mesenchyme-dependent differentiation of epithelial progenitor cells in the gut J Pediatr Gastroenterol Nutr 6 14-23 1:STN:280:BiiD1cngslU%3D 3540259
3. BM Gumbiner 1992 Epithelial morphogenesis Cell 69 385-7 10.1016/ 0092-8674(92)90440-N 1:CAS:528:DyaK38XktVClurc%3D 1581959
4. NA Bhowmick A Chytil D Plieth AE Gorska N Dumont S Shappell 2004 TGF-beta signaling in fibroblasts modulates the oncogenic potential of adjacent epithelia Science 303 848-51 10.1126/science.1090922 1:CAS:528:DC%2BD2cXovVKmtQ%3D%3D 14764882
5. S Yasugi 1993 Role of epithelial-mesenchymal interactions in differentiation of epithelium of vertebrate digestive organs Dev Growth Differ 35 1-9 10.1111/j.1440-169X.1993.00001.x
6. RL Juliano S Haskill 1993 Signal transduction from the extracellular matrix J Cell Biol 120 577-85 10.1083/jcb.120.3.577 1:CAS:528:DyaK3sXnslKjug%3D%3D 8381117
7. ED Hay 1993 Extracellular matrix alters epithelial differentiation Curr Opin Cell Biol 5 1029-35 10.1016/0955-0674(93)90088-8 1:CAS:528:DyaK2cXltVOjtA%3D%3D 8129940
8. GR van den Brink JC Hardwick GN Tytgat MA Brink FJ Ten Kate SJ Van Deventer 2001 Sonic hedgehog regulates gastric gland morphogenesis in man and mouse Gastroenterology 121 317-28 10.1053/gast.2001.26261 1:CAS:528:DC%2BD3MXmsVyms7w%3D 11487541
9. T Halttunen A Marttinen I Rantala H Kainulainen M Maki 1996 Fibroblasts and transforming growth factor beta induce organization and differentiation of T84 human epithelial cells Gastroenterology 111 1252-62 10.1053/gast.1996.v111.pm8898639 1:CAS:528:DyaK28XmvFygsb0%3D 8898639
10. AU Dignass S Tsunekawa DK Podolsky 1994 Fibroblast growth factors modulate intestinal epithelial cell growth and migration Gastroenterology 106 1254-62 1:STN:280:ByuB38bks1E%3D 7513666
11. C Fritsch EA Swietlicki O Lefebvre M Kedinger H Iordanov MS Levin 2002 Epimorphin expression in intestinal myofibroblasts induces epithelial morphogenesis J Clin Invest 110 1629-41 10.1172/JCI200213588 1:CAS:528:DC%2BD38Xptlarsrk%3D 12464668
12. R Montesano K Matsumoto T Nakamura L Orci 1991 Identification of a fibroblast-derived epithelial morphogen as hepatocyte growth factor Cell 67 901-8 10.1016/0092-8674(91)90363-4 1:CAS:528:DyaK38XhvFGhuw%3D%3D 1835669
13. T Narita K Saitoh T Kameda A Kuroiwa M Mizutani C Koike 2000 BMPs are necessary for stomach gland formation in the chicken embryo: A study using virally induced BMP-2 and Noggin expression Development 127 981-8 1:CAS:528:DC%2BD3cXit1aqu74%3D 10662637
14. JM Wozney V Rosen AJ Celeste LM Mitsock MJ Whitters RW Kriz 1988 Novel regulators of bone formation: Molecular clones and activities Science 242 1528-34 10.1126/science.3201241 1:CAS:528:DyaL1MXkvFantr8%3D 3201241
15. K Miyazono K Kusanagi H Inoue 2001 Divergence and convergence of TGF-beta/BMP signaling J Cell Physiol 187 265-76 10.1002/jcp.1080 1:CAS:528:DC%2BD3MXjtF2isbk%3D 11319750
16. JM Wozney 1992 The bone morphogenetic protein family and osteogenesis Mol Reprod Dev 32 160-7 10.1002/mrd.1080320212 1:CAS:528:DyaK38XltVCgtrk%3D 1637554
17. BL Hogan 1996 Bone morphogenetic proteins: Multifunctional regulators of vertebrate development Genes Dev 10 1580-94 1:CAS:528:DyaK28Xkt1CksL4%3D 8682290
18. T Koike S Yasugi 1999 In vitro analysis of mesenchymal influences on the differentiation of stomach epithelial cells of the chicken embryo Differentiation 65 13-25 10.1046/j.1432-0436.1999.6510013.x 1:STN:280:DyaK1MznslygsA%3D%3D 10448710
19. V Romano M Hatzfeld TM Magin R Zimbelmann WW Franke G Maier 1986 Cytokeratin expression in simple epithelia. I. Identification of mRNA coding for human cytokeratin no. 18 by a cDNA clone Differentiation 30 244-53 10.1111/j.1432-0436.1986.tb00787.x 1:CAS:528:DyaL28XktVWlsr8%3D 2422083
20. J Bara E Chastre J Mahiou RL Singh ME Forgue-Lafitte E Hollande 1998 Gastric M1 mucin, an early oncofetal marker of colon carcinogenesis, is encoded by the MUC5AC gene Int J Cancer 75 767-73 10.1002/ (SICI)1097-0215(19980302)75:5<767::AID-IJC17>3.0.CO;2-3 1:CAS:528:DyaK1cXhsVymtLk%3D 9495247
21. SB Ho AM Roberton LL Shekels CT Lyftogt GA Niehans NW Toribara 1995 Expression cloning of gastric mucin complementary DNA and localization of mucin gene expression Gastroenterology 109 735-47 10.1016/ 0016-5085(95)90380-1 1:CAS:528:DyaK2MXos1Grurw%3D 7657101
22. C De Bolos M Garrido FX Real 1995 MUC6 apomucin shows a distinct normal tissue distribution that correlates with Lewis antigen expression in the human stomach Gastroenterology 109 723-34 10.1016/0016-5085(95)90379-8 1:CAS:528:DyaK2MXos1Grur8%3D 7657100
23. RH Wetzels R Holland UJ van Haelst EB Lane IM Leigh FC Ramaekers 1989 Detection of basement membrane components and basal cell keratin 14 in noninvasive and invasive carcinomas of the breast Am J Pathol 134 571-9 1:STN:280:BiaC28vktF0%3D 2466404
24. OF Santos SK Nigam 1993 HGF-induced tubulogenesis and branching of epithelial cells is modulated by extracellular matrix and TGF-beta Dev Biol 160 293-302 10.1006/dbio.1993.1308 1:CAS:528:DyaK2cXhsVeq 8253265
25. JV Soriano MS Pepper T Nakamura L Orci R Montesano 1995 Hepatocyte growth factor stimulates extensive development of branching duct-like structures by cloned mammary gland epithelial cells J Cell Sci 108 2 413-30 1:CAS:528:DyaK2MXktFSjsr8%3D 7768990
26. R Montesano G Schaller L Orci 1991 Induction of epithelial tubular morphogenesis in vitro by fibroblast-derived soluble factors Cell 66 697-711 10.1016/0092-8674(91)90115-F 1:CAS:528:DyaK3MXlslKjsLY%3D 1878968
27. AE Sirica TW Gainey 1997 A new rat bile ductular epithelial cell culture model characterized by the appearance of polarized bile ducts in vitro Hepatology 26 537-49 1:STN:280:ByiH2cjnsVQ%3D 9303480
28. J Jacquot C Spilmont H Burlet C Fuchey AC Buisson JM Tournier 1994 Glandular-like morphogenesis and secretory activity of human tracheal gland cells in a three-dimensional collagen gel matrix J Cell Physiol 161 407-18 10.1002/jcp.1041610303 1:CAS:528:DyaK2MXisVCksb0%3D 7962124
29. MJ Bitgood AP McMahon 1995 Hedgehog and Bmp genes are coexpressed at many diverse sites of cell-cell interaction in the mouse embryo Dev Biol 172 126-38 10.1006/dbio.1995.0010 1:CAS:528:DyaK2MXptFGru7Y%3D 7589793
30. XZ Wen S Miyake Y Akiyama Y Yuasa 2004 BMP-2 modulates the proliferation and differentiation of normal and cancerous gastric cells Biochem Biophys Res Commun 316 100-6 10.1016/j.bbrc.2004.02.016 1:CAS:528:DC%2BD2cXhslentrg%3D 15003517
31. N Jonckheere M Van Der Sluis A Velghe MP Buisine M Sutmuller MP Ducourouble 2004 Transcriptional activation of the murine Muc5ac mucin gene in epithelial cancer cells by TGF-beta/Smad4 signalling pathway is potentiated by Sp1 Biochem J 377 797-808 1:CAS:528:DC%2BD2cXls1Grtg%3D%3D 14570593
32. A Schmassmann C Stettler R Poulsom N Tarasova C Hirschi B Flogerzi 1997 Roles of hepatocyte growth factor and its receptor Met during gastric ulcer healing in rats Gastroenterology 113 1858-72 10.1016/ S0016-5085(97)70005-2 1:CAS:528:DyaK2sXotFSluro%3D 9394725
33. S Tsuji S Kawano M Tsujii H Fusamoto T Kamada 1995 Roles of hepatocyte growth factor and its receptor in gastric mucosa. A cell biological and molecular biological study Dig Dis Sci 40 1132-9 10.1007/BF02064211 1:CAS:528:DyaK2MXmt1Klsrw%3D 7729276
34. M Takahashi S Ota T Shimada E Hamada T Kawabe T Okudaira 1995 Hepatocyte growth factor is the most potent endogenous stimulant of rabbit gastric epithelial cell proliferation and migration in primary culture J Clin Invest 95 1994-2003 1:CAS:528:DyaK2MXltlWrtr8%3D 7738166
35. MA Hull JL Brough DG Powe GI Carter D Jenkins CJ Hawkey 1998 Expression of basic fibroblast growth factor in intact and ulcerated human gastric mucosa Gut 43 525-36 1:CAS:528:DyaK1cXmvFanur4%3D 9824581
36. Y Kinoshita H Nakata S Hassan M Asahara C Kawanami Y Matsushima 1995 Gene expression of keratinocyte and hepatocyte growth factors during the healing of rat gastric mucosal lesions Gastroenterology 109 1068-77 10.1016/0016-5085(95)90564-2 1:CAS:528:DyaK2MXos1aqtLY%3D 7557071
37. M Kretzschmar F Liu A Hata J Doody J Massague 1997 The TGF-beta family mediator Smad1 is phosphorylated directly and activated functionally by the BMP receptor kinase Genes Dev 11 984-95 1:CAS:528:DyaK2sXivFWgsb8%3D 9136927
38. CH Heldin K Miyazono PTG ten Dijke 1997 F-beta signalling from cell membrane to nucleus through SMAD proteins Nature 390 465-71 10.1038/ 37284 1:CAS:528:DyaK2sXnvFyrtLo%3D 9393997
39. PA Hoodless T Haerry S Abdollah M Stapleton MB O'Connor L Attisano 1996 MADR1, a MAD-related protein that functions in BMP2 signaling pathways Cell 85 489-500 10.1016/S0092-8674(00)81250-7 1:CAS:528:DyaK28XjtFyitrc%3D 8653785