메뉴 건너뛰기




Volumn 38, Issue 11, 2006, Pages 727-731

The primary amine metabolite of sibutramine stimulates lipolysis in adipocytes isolated from lean and obese mice and in isolated human adipocytes

Author keywords

adrenoceptors; Lipolysis; M2; Sibutramine; White adipose tissue

Indexed keywords

1 (2 ETHYLPHENOXY) 3 (1,2,3,4 TETRAHYDRO 1 NAPHTHYLAMINO) 2 PROPANOL OXALATE; 1 [1 (4 CHLOROPHENYL)CYCLOBUTYL] 3 METHYL 1 METHYLAMINOBUTANE; 1 AMINO 1 [1 (4 CHLOROPHENYL)CYCLOBUTYL] 3 METHYLBUTANE; 3 ISOPROPYLAMINO 1 (7 METHYL 4 INDANYLOXY) 2 BUTANOL; 4 [2 [[2 (3 CHLOROPHENYL) 2 HYDROXYETHYL]AMINO]PROPYL]PHENOXYACETIC ACID; AMINE; ATENOLOL; GLYCEROL; ISOPRENALINE; PRAZOSIN; PROPANOL; SIBUTRAMINE; YOHIMBINE;

EID: 33845367675     PISSN: 00185043     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2006-955083     Document Type: Article
Times cited : (6)

References (26)
  • 4
    • 12944308320 scopus 로고    scopus 로고
    • Sibutramine in the treatment of obesity in type 2 diabetic patients and in nondiabetic subjects
    • Tankova T, Dakovska G, Lazarova M, Dakovska L, Kirilov G, Koev D. Sibutramine in the treatment of obesity in type 2 diabetic patients and in nondiabetic subjects. Acta Diabetol 2004; 41: 146-153
    • (2004) Acta Diabetol , vol.41 , pp. 146-153
    • Tankova, T.1    Dakovska, G.2    Lazarova, M.3    Dakovska, L.4    Kirilov, G.5    Koev, D.6
  • 5
    • 1442301554 scopus 로고    scopus 로고
    • Clinical use of sibutramine
    • (Barc)
    • Ryan DH. Clinical use of sibutramine. Drugs Today (Barc) 2004; 40: 41-54
    • (2004) Drugs Today , vol.40 , pp. 41-54
    • Ryan, D.H.1
  • 6
    • 0036945748 scopus 로고    scopus 로고
    • Sibutramine: Its mode of action and efficacy
    • Finer N. Sibutramine: its mode of action and efficacy. Int J Obes Relat Metab Disord 2002; 26: 29-33
    • (2002) Int J Obes Relat Metab Disord , vol.26 , pp. 29-33
    • Finer, N.1
  • 7
    • 15944371577 scopus 로고    scopus 로고
    • Effect of sibutramine on weight management and metabolic control in type 2 diabetes: A meta-analysis of clinical studies
    • Vettor R, Serra R, Fabris R, Pagano C, Federspil G. Effect of sibutramine on weight management and metabolic control in type 2 diabetes: a meta-analysis of clinical studies. Diabetes Care 2005; 28: 942-949
    • (2005) Diabetes Care , vol.28 , pp. 942-949
    • Vettor, R.1    Serra, R.2    Fabris, R.3    Pagano, C.4    Federspil, G.5
  • 8
    • 0032434821 scopus 로고    scopus 로고
    • Sibutramine. A review of its contribution to the management of obesity
    • McNeely W, Goa KL. Sibutramine. A review of its contribution to the management of obesity. Drugs 1998; 56: 1093-1124
    • (1998) Drugs , vol.56 , pp. 1093-1124
    • McNeely, W.1    Goa, K.L.2
  • 10
    • 0036735737 scopus 로고    scopus 로고
    • Mechanism of the thermogenic effect of Metabolite 2 (BTS 54 505), a major pharmacologically active metabolite of the novel anti-obesity drug, sibutramine
    • Liu YL, Heal DJ, Stock MJ. Mechanism of the thermogenic effect of Metabolite 2 (BTS 54 505), a major pharmacologically active metabolite of the novel anti-obesity drug, sibutramine. Int J Obes Relat Metab Disord 2002; 26: 1245-1253
    • (2002) Int J Obes Relat Metab Disord , vol.26 , pp. 1245-1253
    • Liu, Y.L.1    Heal, D.J.2    Stock, M.J.3
  • 11
    • 0037183743 scopus 로고    scopus 로고
    • Comparison of the thermogenic and hypophagic effects of sibutramine's metabolite 2 and other monoamine reuptake inhibitors
    • Liu YL, Connoley IP, Harrison J, Heal DJ, Stock MJ. Comparison of the thermogenic and hypophagic effects of sibutramine's metabolite 2 and other monoamine reuptake inhibitors. Eur J Pharmacol 2002; 452: 49-56
    • (2002) Eur J Pharmacol , vol.452 , pp. 49-56
    • Liu, Y.L.1    Connoley, I.P.2    Harrison, J.3    Heal, D.J.4    Stock, M.J.5
  • 12
    • 0031837935 scopus 로고    scopus 로고
    • Effect of the antiobesity agent sibutramine in obese-diabetic ob/ob mice
    • Day C, Bailey CJ. Effect of the antiobesity agent sibutramine in obese-diabetic ob/ob mice. Int J Obes Relat Metab Disord 1998; 22: 619-623
    • (1998) Int J Obes Relat Metab Disord , vol.22 , pp. 619-623
    • Day, C.1    Bailey, C.J.2
  • 13
    • 0019471997 scopus 로고
    • Abnormal plasma glucose and insulin responses in heterozygous lean (ob/+) mice
    • Flatt PR, Bailey CJ. Abnormal plasma glucose and insulin responses in heterozygous lean (ob/+) mice. Diabetologia 1981; 20: 573-577
    • (1981) Diabetologia , vol.20 , pp. 573-577
    • Flatt, P.R.1    Bailey, C.J.2
  • 14
    • 0020086017 scopus 로고
    • Influence of genetic background and age on the expression of the obese hyperglycaemic syndrome in Aston ob/ob mice
    • Bailey CJ, Flatt PR, Atkins TW. Influence of genetic background and age on the expression of the obese hyperglycaemic syndrome in Aston ob/ob mice. Int J Obes 1982; 6: 11-21
    • (1982) Int J Obes , vol.6 , pp. 11-21
    • Bailey, C.J.1    Flatt, P.R.2    Atkins, T.W.3
  • 15
    • 78651166782 scopus 로고
    • Metabolism of isolated fat cells. I. Effects of hormones on glucose metabolism and lipolysis
    • Rodbell M. Metabolism of isolated fat cells. I. Effects of hormones on glucose metabolism and lipolysis. J Biol Chem 1964; 239: 375-380
    • (1964) J Biol Chem , vol.239 , pp. 375-380
    • Rodbell, M.1
  • 17
    • 0001118775 scopus 로고
    • Glycerol UV method
    • Bergmeyer HU (ed). London: Academic Press
    • Wieland O. Glycerol UV method. In: Bergmeyer HU (ed). Methods of Enzymatic Analysis. London: Academic Press, 1974; 1404-1409
    • (1974) Methods of Enzymatic Analysis , pp. 1404-1409
    • Wieland, O.1
  • 18
    • 0030860731 scopus 로고    scopus 로고
    • Comparison of the effects of sibutramine and other monoamine reuptake inhibitors on food intake in the rat
    • Jackson HC, Needham AM, Hutchins LJ, Mazurkiewicz SE, Heal DJ. Comparison of the effects of sibutramine and other monoamine reuptake inhibitors on food intake in the rat. Br J Pharmacol 1997; 121: 1758-1762
    • (1997) Br J Pharmacol , vol.121 , pp. 1758-1762
    • Jackson, H.C.1    Needham, A.M.2    Hutchins, L.J.3    Mazurkiewicz, S.E.4    Heal, D.J.5
  • 19
    • 0031820091 scopus 로고    scopus 로고
    • Sibutramine: A novel anti-obesity drug. A review of the pharmacological evidence to differentiate it from d-amphetamine and d-fenfluramine
    • Heal DJ, Aspley S, Prow MR, Jackson HC, Martin KF, Cheetham SC. Sibutramine: a novel anti-obesity drug. A review of the pharmacological evidence to differentiate it from d-amphetamine and d-fenfluramine. Int J Obes Relat Metab Disord 1998; 22: 18-28
    • (1998) Int J Obes Relat Metab Disord , vol.22 , pp. 18-28
    • Heal, D.J.1    Aspley, S.2    Prow, M.R.3    Jackson, H.C.4    Martin, K.F.5    Cheetham, S.C.6
  • 21
    • 0033956149 scopus 로고    scopus 로고
    • Modalities of the food intake-reducing effect of sibutramine in humans
    • Chapelot D, Marmonier C, Thomas F, Hanotin C. Modalities of the food intake-reducing effect of sibutramine in humans. Physiol Behav 2000; 68: 299-308
    • (2000) Physiol Behav , vol.68 , pp. 299-308
    • Chapelot, D.1    Marmonier, C.2    Thomas, F.3    Hanotin, C.4
  • 22
    • 0037499534 scopus 로고    scopus 로고
    • Short-term effects of sibutramine (Reductil) on appetite and eating behaviour and the long-term therapeutic outcome
    • Barkeling B, Elfhag K, Rooth P, Rossner S. Short-term effects of sibutramine (Reductil) on appetite and eating behaviour and the long-term therapeutic outcome. Int J Obes Relat Metab Disord 2003; 27: 693-700
    • (2003) Int J Obes Relat Metab Disord , vol.27 , pp. 693-700
    • Barkeling, B.1    Elfhag, K.2    Rooth, P.3    Rossner, S.4
  • 24
    • 0030811318 scopus 로고    scopus 로고
    • Regional lipolytic responses to isoproterenol in women
    • Guo A, Johnson M, Jensen MD. Regional lipolytic responses to isoproterenol in women. Am Physiol Soc 1997; 273: 108-112
    • (1997) Am Physiol Soc , vol.273 , pp. 108-112
    • Guo, A.1    Johnson, M.2    Jensen, M.D.3
  • 25
    • 0027536169 scopus 로고
    • Coexistence of beta 1-, beta 2-, and beta 3-adrenoceptors in dog fat cells and their differential activation by catecholamines
    • Galitzky J, Reverte M, Portillo M, Carpene C, Lafontan M, Berlan M. Coexistence of beta 1-, beta 2-, and beta 3-adrenoceptors in dog fat cells and their differential activation by catecholamines. Am J Physiol 1993; 264: 403-412
    • (1993) Am J Physiol , vol.264 , pp. 403-412
    • Galitzky, J.1    Reverte, M.2    Portillo, M.3    Carpene, C.4    Lafontan, M.5    Berlan, M.6
  • 26
    • 0034878265 scopus 로고    scopus 로고
    • Effects of sibutramine on body weight and serum lipids: A double-blind, randomized, placebo-controlled study in 322 overweight and obese patients with dyslipidemia
    • Sibutramine Study Group
    • Dujovne CA, Zavoral JH, Rowe E, Mendel CM. Sibutramine Study Group. Effects of sibutramine on body weight and serum lipids: a double-blind, randomized, placebo-controlled study in 322 overweight and obese patients with dyslipidemia. Am Heart J 2001; 142: 489-497
    • (2001) Am Heart J , vol.142 , pp. 489-497
    • Dujovne, C.A.1    Zavoral, J.H.2    Rowe, E.3    Mendel, C.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.