Testicular morphology and expression of aromatase in testes of mice with the mosaic mutation (Atp7amo-ms)

Theriogenology

Volumn 67, Issue 2, 2007, Pages 423-434

  Kotula Balak, Małgorzata ^a   Lenartowicz, Małgorzata ^a   Kowal, Małgorzata ^a   Styrna, Józefa ^a   Bilińska, Barbara ^a  

^a JAGIELLONIAN UNIVERSITY   (Poland)

Author keywords

Apoptosis; Aromatase; Mosaic mutation; Sex steroid hormones; Testis

Indexed keywords

ADENOSINE TRIPHOSPHATASE; ANDROGEN; AROMATASE; ATP7A PROTEIN, MOUSE; CATION TRANSPORT PROTEIN; COPPER; ESTROGEN;

ANIMAL; ANIMAL DISEASE; ARTICLE; ENZYMOLOGY; GENETICS; IMMUNOHISTOCHEMISTRY; LETHAL GENE; LEYDIG CELL; MALE; METABOLISM; MOLECULAR WEIGHT; MOUSE; MUTATION; NICK END LABELING; PATHOLOGY; PHYSIOLOGY; TESTIS; WESTERN BLOTTING; Y CHROMOSOME;

ADENOSINE TRIPHOSPHATASES; ANDROGENS; ANIMALS; AROMATASE; BLOTTING, WESTERN; CATION TRANSPORT PROTEINS; COPPER; ESTROGENS; GENES, LETHAL; IMMUNOHISTOCHEMISTRY; IN SITU NICK-END LABELING; LEYDIG CELLS; MALE; MICE; MOLECULAR WEIGHT; MUTATION; TESTIS; Y CHROMOSOME;

EID: 33845319786     PISSN: 0093691X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.theriogenology.2006.08.016     Document Type: Article

References (65)

1. Almadhidi J., Seralini G.E., Fresnel J., Silberzachn P., and Gaillard J. Immunohistochemical localization of cytochrome P450 aromatase in equine gonads. J Histochem Cytochem 43 (1995) 571-577
2. Bilińska B., Leśniak M., and Schmalz B. Are ovine Leydig cells able to aromatize androgens?. Reprod Fertil Develop 9 (1997) 193-199
3. Hess R.A. Estrogen in the adult male reproductive tract: a review. Reprod Biol Endocrinol 1 (2003) 52-58
4. Carreau S., Genissel C., Bilińska B., and Levallet J. Sources of oestrogen in the testis and reproductive tract of the male. Int J Androl 22 (1999) 211-223
5. O'Donnell L., Robertson K.M., Jones M.E., and Simpson E.R. Estrogen and spermatogenesis. Endocr Rev 22 (2001) 289-318
6. Kwon S., Hess R.A., Bunick D., Nitta H., Janulis L., Osawa Y., et al. Rooster testicular germ cells and epididymal sperm contain P450 aromatase. Biol Reprod 53 (1995) 1259-1264
7. Janulis L., Hess R.A., Bunick D., Nitta H., Janssen S., Osawa Y., et al. Mouse epididymal sperm contain active P450 aromatase which decreases as sperm traverse the epididymis. J Androl 17 (1996) 111-116
8. Aquila S., Sisci D., Gentile M., Middea E., Siciliano L., and Ando S. Human ejaculated spermatozoa contain active P450 aromatase. J Clin Endocrinol Metab 87 (2002) 3385-3390
9. Rago V., Bilińska B., Palma A., Ando S., and Carpino A. Evidence of aromatase localization in cytoplasmic droplet of human immature ejaculated spermatozoa. Folia Histochem Cytobiol 41 (2003) 23-27
10. Lambard S., Galeraud-Denis I., Bouraima H., Bourguiba S., Chocat A., and Carreau S. Expression of aromatase in human ejaculated spermatozoa: a putative marker of motility. Mol Hum Reprod 9 (2003) 117-124
11. Eddy E.M., Washburn T.F., Bunch D.O., Goulding E.H., Gladen B.C., Lubahn D.B., et al. Targeted disruption of the oestrogen receptor gene in male mice causes alteration of spermatogenesis and infertility. Endocrinology 137 (1996) 4796-4805
12. Robertson K.M., O'Donnell L., Jones M.E.E., Meachem S.J., Boon W.C., Fisher C.R., et al. Impairment of spermatogenesis in mice lacking a functional aromatase (cyp 19) gene. Proc Natl Acad Sci USA 96 (1996) 7986-7991
13. Couse J.F., and Korach K.S. Estrogen receptor null mice: what have we learned and where will they lead us?. Endocr Rev 20 (1999) 358-417
14. Lambard S., Silandre D., Delalande C., Denis-Galeraund I., Bourguiba S., and Carreau S. Aromatase in testis: expression and role in male reproduction. J Steroid Biochem Mol Biol 95 (2005) 63-69
15. Bedwal R.S., and Bahuguna A. Zinc, copper and selenium in reproduction. Experientia 50 (1994) 626-640
16. Danks D.M. Copper deficiency in humans. Annu Rev Nutr 8 (1988) 235-257
17. Krzanowska H. New mutation. Mouse News Lett 35 (1966) 34-35
18. Styrna J. Analysis of causes of lethality in mice with the Ms (mosaic) gene. Genet Polon 18 (1977) 61-79
19. Gitshier J., Motaff B., Reilly D., Wood W.I., and Fairbrother W.J. Solution structure of the fourth metal-binding domain from the Menkes copper-transporting ATPase. Nat Struct Biol 5 (1998) 47-54
20. Lenartowicz M., and Sasuła K. Altered copper metabolism in the mosaic mutant mice. Nutr Res 10 (2000) 1519-1529
21. Styrna J., Szkawran H., and Szerszeń B. The effect of copper injection on the Ms (mosaic) males. Zwierzeta Lab 15 (1978) 77-83
22. Bilińska B., and Litwin J. Immunocytochemical demonstration of peroxisomes in cultured Leydig cells: a decrease in testosterone secretion precedes reduction of peroxisomes. Eur J Histochem 39 (1995) 273-280
23. Schumacher M., Schafer G., Holstein A.F., and Hilz H. Rapid isolation of mouse Leydig cells by centrifugation in Percoll density gradients with complete retention of morphological and biochemical integrity. FEBS Lett 91 (1978) 333-338
24. Levallet J., Bilińska B., Mittre H., Genissel C., Fresnel J., and Carreau S. Expression and immunolocalization of functional cytochrome P450 aromatase in mature rat testicular cells. Biol Reprod 58 (1998) 919-926
25. Kotula-Balak M., Gancarczyk M., Sadowska J., and Bilińska B. The expression of estrogen receptors α and β in mouse Leydig cells in vitro that derived from cryptorchid males. Eur J Histochem 49 (2005) 395-402
26. Sambrook J., Fritsch E.F., and Maniatis T. Detection and analysis of proteins expressed from cloned genes. In: Ford N., Nolan C., and Ferguson C. (Eds). Molecular cloning. A laboratory manual (1989), Cold Spring Laboratory Press, Cold Spring, NY, USA 18.60-18.67
27. Dufau M.L., Catt K.J., Tsuruhara T., and Ryan D. Radioimmunoassay of plasma testosterone. Chim Acta 37 (1972) 109-116
28. Hotchkiss J., Atkinson L.E., and Knobil E. Time course of serum estrogen and luteinizing hormone concentrations during menstrual cycle of rhesus monkey. Endocrinology 89 (1971) 177-183
29. Robertson K.M., Jones M.E., and Simpson E.R. Estrogen and spermatogenesis. Endocr Rev 22 (2001) 289-318
30. Carreau S., Lambard S., Delalande C., Denis-Galeraud I., Bilińska B., and Bourguiba S. Aromatase expression and role of estrogens in male gonad: a review. Reprod Biol Endocrinol 1 (2003) 35-42
31. Hess R.A., Bunick D., Lee K.H., Bahr J., Taylor J.A., Korach K.S., et al. A role for oestrogen in the male reproductive tract. Nature 390 (1997) 509-512
32. Radochońska A. Effect of the gene mosaic (Ms) on growth rate, weight of organs and hair structure in mouse. Genet Polon 11 (1970) 257-274
33. Rodriguez I., Ody C., Araki K., Garcia I., and Vasselli P. An early and massive wave of germinal cell apoptosis is required for the developed of functional spermatogenesis. EMBO J 16 (1997) 2262-2270
34. Koji T. Male germ cell death in mouse testes: possible involvement of Fas and Fas ligand. Med Electr Microsc 34 (2001) 213-222
35. Ren X.Y., Zhou Y., Zhang J.P., Feng W.H., and Jiao B.H. Metallotioneine gene expression under different time in testicular Sertoli and spermatogenic cells of the rats treated with cadmium. Reprod Toxicol 17 (2003) 219-227
36. Kowal M., Kotula-Balak M., Styrna J., and Bilińska B. Immunohistochemical localization of androgen receptors in testicular cells of mice with mosaic mutation. Folia Histochem Cytobiol 40 (2002) 161-162
37. Lenartowicz M., Sasuła K., and Zawadowska B. Alterations in kidney morphology in mice with mosaic mutation. Folia Histochem Cytobiol 39 (2001) 275-818
38. Lenartowicz M., Kowal M., Buda-Lewandowska D., and Styrna J. Pathological structure of the kidney from the adult mice with mosaic mutation. J Inherit Metab Dis 23 (2003) 1-13
39. Hummel K.P., Richardson F.L., and Fekete E. Biology of the laboratory mouse. In: Green E.L. (Ed). Anatomy (1966), McGraw-Hill Book Company, New York 247-307
40. Nitta H., Bunick D., Hess R.A., Janulis L., Newton S.C., Millette C.F., et al. Germ cells of mouse testis express P450 aromatase. Endocrinology 132 (1993) 1396-1401
41. Tsubota T., Nitta H., Osawa Y., Mason I.J., Kita I., Tiba T., et al. Immunolacalization of steroidogenic enzymes, P450scc, 3β-HSD, P450c17, and P450arom in the Hokkaido brown bear (Ursus arctos yesoensis) testis. Gen Comp Endocr 92 (1993) 439-444
42. Inkster S., Yue W., and Brodie A. Human testicular aromatase: immunocytochemical and biochemical studies. J Clin Endocr Metab 80 (1995) 1941-1947
43. Bilińska B., Schmalz-Fra{ogonek}czek B., Sadowska J., and Carreau S. Immunolocalization of cytochrome P450 aromatase and estrogen receptors α and β in bank vole testicular cells. Acta Histochem 102 (2000) 167-181
44. Bilińska B., Schmalz-Fra{ogonek}czek B., Kotula M., and Carreau S. Photoperiod-dependent capability of androgen aromatization and the role of estrogens in the bank vole testis visualized by means of immunohistochemistry. Mol Cell Endocrinol 178 (2001) 189-198
45. Carpino A., Pezzi V., Rago V., Bilińska B., and Ando S. Immunolocalization of cytochrome P450 aromatase in rat testis during postnatal development. Tissue Cell 33 (2001) 349-353
46. Turner K.J., Macpherson S., Millar M.R., McNeilly A.S., Williams K., Cranfield M., et al. Development and validation of a new monoclonal antibody to mammalian aromatase. J Endocrinol 172 (2002) 21-30
47. Hejmej A., Gorazd M., Kosiniak-Kamysz K., Wiszniewska B., Sadowska J., and Bilińska B. Expression of aromatase and estrogen receptors in the reproductive tissues of the stallion and a single cryptorchid visualised by means of immunohistochemistry. Domest Anim Endocrinol 29 (2005) 534-547
48. 1 hybrids in maturation age. Acta Biol Crac 14 (1971) 73-84
49. Krzanowska H., and Bilińska B. Number of chromocentres in the nuclei of mouse Sertoli cells in relation to the strain and age of males from puberty to senescence. J Reprod Fertil 118 (2000) 343-350
50. Bilińska B., Kotula-Balak M., Gancarczyk M., Sadowska J., Tabarowski Z., and Wojtusiak A. Androgen aromatization in cryptorchid mouse testes. Acta Histochem 105 (2003) 57-65
51. Kotula-Balak M., Grzmil P., Styrna J., and Bilińska B. Immunodetection of aromatase in mice with a partial deletion in the long arm of the Y chromosome. Acta Histochem 106 (2004) 55-64
52. Li X., Nokkala E., Yan W., Streng T., Saarinen N., Warri A., et al. Altered structure and function of reproductive organs in transgenic male mice overexpressing human aromatase. Endocrinology 142 (2001) 2435-2442
53. Sharpe R. The roles of oestrogen in the male. Trends Endocrin Met 9 (1998) 371-377
54. Hilakivi-Clarke L., Cho E., and Onojafe I. High-fat diet induces aggressive behavior in male mice and rats. Life Sci 58 (1996) 1653-1660
55. Trainor B.C., Kyomen H.H., and Marler C.A. Estrogenic encounters: how interactions between aromatase and the environment modulate aggression. Front Neuroendocrin (2005) [Epub ahead of print]
56. Atanassova N., McKinnell C., Walker M., Turner K.J., Fisher J.S., Morley M., et al. Permanent effects of neonatal estrogen exposure in rats on reproductive hormone levels, Sertoli cell number, and the efficiency of spermatogenesis in adulthood. Endocrinology 140 (1999) 5364-7311
57. Toyama Y., Hosoi I., Ichikawa S., Maruoka M., Yashiro E., Ito H., et al. 17β-Estradiol 3-benzoate affects spermatogenesis in the adult mouse. Mol Cell Endocrinol 178 (2001) 161-168
58. Gancarczyk M., Paziewska-Hejmej A., Carreau S., Tabarowski Z., and Bilińska B. Dose- and photoperiod-dependent effect of 17β-estradiol or ICI 182, 780 administration on testicular structure, acceleration of spermatogenesis, and aromatase immunoexpression in immature bank voles. Acta Histochem 106 (2004) 269-278
59. Saylor W.W., and Downer J.V. Copper and zinc distribution in liver and oviduct of estrogen and testosterone treated hens. Nutr Res 6 (1986) 181-190
60. Fields M., Lewis C., Scholfield D., Powel A.S., Rose A.J., Reiser S., et al. Female rats are protected against the fructose induced mortality of copper deficiency. Proc Soc Exp Biol Med 183 (1987) 145-149
61. 2+ deficiency and overload in the male rat: measurement of certain parameters of testicular and spermatozoan activity. Compt Rend Sci Soc Biol 180 (1986) 151-158
62. Hafiez A.A., El-Kirdassay Z.H., El-Malkh N.M., and El-Zayat E.M. Role of zinc in regulating the testicular function. Part 3. Histopathological changes induced by dietary zinc deficiency in testes of male albino rats. Nahrung 34 (1990) 65-73
63. Hartoma T.R., Nahoul K., and Nettem A. Zinc, plasma androgens and male sterility. Lancet 26 (1977) 1125-1126
64. Behne D., Weiler H., and Kyriakopoulos A. Effects of selenium deficiency on testicular morphology and function in rats. J Reprod Fertil 106 (1996) 291-297
65. Ursini F., Heim S., Kiess M., Maiorino M., Roveri A., Wissing J., et al. Dual function of the selenoprotein PHGPx during sperm maturation. Science 27 (1999) 1393-1396