Functional identification of a protein inhibitor of neuronal nitric oxide synthase of Taenia solium metacestode

Molecular and Biochemical Parasitology

Volumn 151, Issue 1, 2007, Pages 41-51

  Kim, Seon Hee ^a   Chung, Joon Yong ^b   Bae, Young An ^a   Cai, Guo Bin ^a   Na, Byoung Kuk ^a   Kim, Nam Joo ^c   Kwack, Han Shik ^c   Kim, Tong Soo ^d   Kong, Yoon ^a  

^a Sungkyunkwan University School of Medicine   (South Korea)

^b Inje University   (South Korea)

^c PaiChai University   (South Korea)

^d Korea Centers for Disease Control and Prevention   (South Korea)

Author keywords

Cellular homeostasis; Neuronal nitric oxide synthase; Nitric oxide; Protein inhibitor of nNOS; Protein protein interaction; Taenia solium metacestode

Indexed keywords

DYNEIN ADENOSINE TRIPHOSPHATASE; NEURONAL NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE INHIBITOR; PROTEIN ANTIBODY; RECOMBINANT PROTEIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE DEHYDROGENASE;

AMINO ACID SEQUENCE; ANIMAL CELL; ANTIBODY SPECIFICITY; ARTICLE; BLADDER WALL; CELL STIMULATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOSOL; DIMERIZATION; FEEDBACK SYSTEM; GENE EXPRESSION; GENE FREQUENCY; GENE ISOLATION; GENETIC CODE; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; INTRON; LIGHT CHAIN; MOLECULAR WEIGHT; MOUSE; MUSCLE; NEUROBLASTOMA CELL; NEUROCYSTICERCOSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PRIORITY JOURNAL; PROTEIN LOCALIZATION; SCOLEX; SEQUENCE HOMOLOGY; TAENIA SOLIUM;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CELL LINE, TUMOR; DIMERIZATION; ENZYME INHIBITORS; HELMINTH PROTEINS; HUMANS; IMMUNOHISTOCHEMISTRY; MOLECULAR SEQUENCE DATA; NADP; NITRIC OXIDE SYNTHASE TYPE I; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID; TAENIA SOLIUM;

TAENIA SOLIUM;

EID: 33845314319     PISSN: 01666851     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molbiopara.2006.10.003     Document Type: Article

References (43)

1. Carpio A., Escobar A., and Hauser W.A. Cysticercosis and epilepsy: a critical review. Epilepsia 39 (1998) 1025-1040
2. Garcia H.H., et al. Taenia solium cysticercosis. Lancet 362 (2003) 547-556
3. Cardona A.E., Restrepo B.I., Jaramillo J.M., and Teale J.M. Development of an animal model for neurocysticercosis: immune response in the central nervous system is characterized by a predominance of gamma delta T cells. J Immunol 162 (1999) 995-1002
4. Escobar A., and Weidenheim K.M. The pathology of neurocysticercosis. In: Singh G., and Prabhakar S. (Eds). Taenia solium cysticercosis: from basic to clinical science (2002), CAB International, Oxford 289-305
5. Terenina N.B., and Gustafsson M.K. Nitric oxide and its target cells in cercaria of Diplostomum chromatophorum: a histochemical and immunocytochemical study. Parasitol Res 89 (2003) 199-206
6. Gustafsson M.K.S., Terenina N.B., Reuter M., and Movsessian S.O. NO nerves and their targets in a tapeworm: An immunocytochemical study of cGMP in Hymenolepis diminuta. Parasitol Res 90 (2003) 148-152
7. Gustafsson M.K.S., Gaivoronskaja T.V., Terenina N.B., and Tolstenkov O.O. The nitrergic nervous system in flatworms. Helminthologia 40 (2003) 79-85
8. Ahmed S.F., Oswald I.P., Caspar P., et al. Developmental differences determine larval susceptibility to nitric oxide-mediated killing in a murine model of vaccination against Schistosoma mansoni. Infect Immun 65 (1997) 219-226
9. Basu N.K., Kole L., Ghosh A., and Das P.K. Isolation of a nitric oxide synthase from the protozoan parasite, Leishmania donovani. FEMS Microbiol Lett 156 (1997) 43-47
10. Kubes P., Suzuki M., and Granger D.N. Nitric oxide: an endogenous modulator of leukocyte adhesion. Proc Natl Acad Sci USA 88 (1991) 4651-4655
11. Li C.Q., and Wogan G.N. Nitric oxide as a modulator of apoptosis. Cancer Lett 226 (2005) 1-15
12. Jaffrey S.R., and Snyder S.H. PIN: an associated protein inhibitor of neuronal nitric oxide synthase. Science 274 (1996) 774-777
13. King S.J., Brown C.L., Maier K.C., Quintyne N.J., and Schroer T.A. Analysis of the dynein-dynactin interaction in vitro and in vivo. Mol Biol Cell 14 (2003) 5089-5097
14. Hemmens B., Woschitz S., Pitters E., et al. The protein inhibitor of neuronal nitric oxide synthase (PIN): characterization of its action on pure nitric oxide synthases. FEBS Lett 430 (1998) 397-400
15. Rubinek T., Rubinfeld H., Hadani M., Barkai G., and Shimon I. Nitric oxide stimulates growth hormone secretion from human fetal pituitaries and cultured pituitary adenomas. Endocrine 28 (2005) 209-216
16. Schnorrer F., Bohmann K., and Nusslein-Volhard C. The molecular motor dynein is involved in targeting swallow and bicoid RNA to the anterior pole of Drosophila oocytes. Nat Cell Biol 2 (2000) 185-190
17. Crepieux P., Kwon H., Leclerc N., et al. I kappaB alpha physically interacts with a cytoskeleton-associated protein through its signal response domain. Mol Cell Biol 17 (1997) 7375-7385
18. Puthalakath H., Huang D.C., O'Reilly L.A., King S.M., and Strasser A. The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex. Mol Cell 3 (1999) 287-296
19. Herzig R.P., Andersson U., and Scarpulla R.C. Dynein light chain interacts with NRF-1 and EWG, structurally and functionally related transcription factors from humans and Drosophila. J Cell Sci 113 (2000) 4263-4273
20. Kohn A.B., Moroz L.L., Lea J.M., and Greenberg R.M. Distribution of nitric oxide synthase immunoreactivity in the nervous system and peripheral tissues of Schistosoma mansoni. Parasitology 122 (2001) 87-92
21. Chung J.Y., Bahk Y.Y., Huh S., Kang S.Y., Kong Y., and Cho S.Y. A recombinant 10-kDa protein of Taenia solium metacestodes specific to active neurocysticercosis. J Infect Dis 180 (1999) 1307-1315
22. Klatt P., Schmidt K., Lehner D., Glatter O., Bachinger H.P., and Mayer B. Structural analysis of porcine brain nitric oxide synthase reveals a role for tetrahydrobiopterin and l-arginine in the formation of an SDS-resistant dimmer. EMBO J 14 (1995) 3687-3695
23. Wei I.H., Huang C.C., Chang H.M., et al. Neuronal NADPH-d/NOS expression in the nodose ganglion of severe hypoxic rats with or without mild hypoxic preconditioning. J Chem Neuroanat 29 (2005) 149-156
24. Liang J., Jaffrey S.R., Guo W., Snyder S.H., and Clardy J. Structure of the PIN/LC8 dimer with a bound peptide. Nat Struct Biol 6 (1999) 735-740
25. Rodriguez-Crespo I., Straub W., Gavilanes F., and Ortiz de Montellano P.R. Binding of dynein light chain (PIN) to neuronal nitric oxide synthase in the absence of inhibition. Arch Biochem Biophys 359 (1998) 297-304
26. Alderton W.K., Cooper C.E., and Knowles R.G. Nitric oxide synthases: structure, function and inhibition. Biochem J 357 (2001) 593-615
27. Hope B.T., Michael G.J., Knigge K.M., and Vincent S.R. Neuronal NADPH diaphorase is a nitric oxide synthase. Proc Natl Acad Sci USA 88 (1991) 2811-2814
28. Vincent S.R., and Kimura H. Histochemical mapping of nitric oxide synthase in the rat brain. Neuroscience 46 (1992) 755-784
29. Yang W., Jones M.K., Fan J., Hughes-Stamm S.R., and McManus D.P. Characterisation of a family of Schistosoma japonicum proteins related to dynein light chains. Biochim Biophys Acta 1432 (1999) 13-26
30. Piedrafita D., Parsons J.C., Sandeman R.M., et al. Antibody-dependent cell-mediated cytotoxicity to newly excysted juvenile Fasciola hepatica in vitro is mediated by reactive nitrogen intermediates. Parasite Immunol 3 (2001) 473-482
31. Boutlis C.S., Weinberg J.B., Baker J., et al. Nitric oxide production and nitric oxide synthase activity in malaria-exposed Papua New Guinean children and adults show longitudinal stability and no association with parasitemia. Infect Immun 72 (2004) 6932-6938
32. Magez S., Radwanska M., Drennan M., et al. Interferon-gamma and nitric oxide in combination with antibodies are key protective host immune factors during Trypanosoma congolense Tc13 Infections. J Infect Dis 193 (2006) 1575-1583
33. Xia Y., Berlowitz C.O., and Zweier J.L. PIN inhibits nitric oxide and superoxide production from purified neuronal nitric oxide synthase. Biochem Biophys Acta 1760 (2006) 1445-1449
34. Fan J., Zhang Q., Tochio H., Li M., and Zhang M. Structural basis of diverse sequence-dependent target recognition by the 8 kDa dynein light chain. J Mol Biol 306 (2001) 97-108
35. Lack G., Homberger-Zizzari E., Folkers G., Scapozza L., and Perozzo R. Recombinant expression and biochemical characterization of the unique elongating beta-ketoacyl-acyl carrier protein synthase involved in fatty acid biosynthesis of Plasmodium falciparum using natural and artificial substrates. J Biol Chem 281 (2006) 9538-9546
36. Andrew P.J., and Mayer B. Enzymatic function of nitric oxide synthases. Cardiovasc Res 43 (1999) 521-531
37. Genestra M., Guedes-Silva D., Souza W.J., et al. Nitric oxide synthase (NOS) characterization in Leishmania amazonensis axenic amastigotes. Arch Med Res 37 (2006) 328-333
38. Hurst W.J., Moroz L.L., Gillette M.U., and Gillete R. Nitric oxide synthase immunolabeling in the molluscan CNS and peripheral tissues. Biochem Biophys Res Commun 262 (1999) 545-548
39. Ahmed B., and Van Den Oord J.J. Expression of the neuronal isoform of nitric oxide synthase (nNOS) and its inhibitor, protein inhibitor of nNOS, in pigment cell lesions of the skin. Br J Dermatol 141 (1999) 12-19
40. Palmer R.M., Ferrige A.G., and Moncada S. Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor. Nature 327 (1987) 524-526
41. Dick T., Ray K., Salz H.K., and Chia W. Cytoplasmic dynein (ddlc1) mutations cause morphogenetic defects and apoptotic cell death in Drosophila melanogaster. Mol Cell Biol 16 (1996) 1966-1977
42. Hoffmann K.F., and Strand M. Molecular identification of a Schistosoma mansoni tegumental protein with similarity to cytoplasmic dynein light chains. J Biol Chem 271 (1996) 26117-26123
43. Tochio H., Ohki S., Zhang Q., Li M., and Zhang M. Solution structure of a protein inhibitor of neuronal nitric oxide synthase. Nat Struct Biol 5 (1998) 965-969