Intrinsic function of S100A8/A9 complex as an anti-inflammatory protein in liver injury induced by lipopolysaccharide in rats

Clinica Chimica Acta

Volumn 376, Issue 1-2, 2007, Pages 197-204

  Ikemoto, Masaki ^a   Murayama, Hiroshi ^b   Itoh, Hiroshi ^a   Totani, Masayuki ^c   Fujita, Masatoshi ^a  

^a Faculty of Medicine   (Japan)

^b YAMASA CORPORATION   (Japan)

^c SHOWA WOMEN'S UNIVERSITY   (Japan)

Author keywords

Acute inflammation; Cytokines; Lipopolysaccharide; Macrophage; Neutrophils; Nitric oxide; Rejection

Indexed keywords

IMMUNOGLOBULIN G; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; NITRATE; NITRIC OXIDE; NITRITE; PROTEIN S 100; S100 A8 A9 PROTEIN COMPLEX; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG ACCUMULATION; DRUG BINDING; IMMUNOREGULATION; IN VIVO STUDY; INFLAMMATION; KIDNEY; LEUKOCYTE; LIVER; LIVER INJURY; LUNG; MALE; MICROSCOPY; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN BLOOD LEVEL; PROTEIN FUNCTION; PROTEIN PURIFICATION; RAT; SPLEEN; TAIL;

ANIMALS; ANTIBODIES, MONOCLONAL; CALGRANULIN A; CALGRANULIN B; DISEASE MODELS, ANIMAL; HEPATITIS; HUMANS; INFLAMMATION MEDIATORS; INTERLEUKIN-6; LIPOPOLYSACCHARIDES; LIVER; MALE; MULTIPROTEIN COMPLEXES; NITRIC OXIDE; RATS; RATS, WISTAR;

EID: 33845305498     PISSN: 00098981     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cca.2006.08.018     Document Type: Article

References (30)

1. Odink K., Gerletti N., Bruggen J., et al. Two calcium-binding proteins in infiltrate macrophages of rheumatoid arthritis. Nature 330 (1987) 80-82
2. Kerkhoff C., Klempt M., and Sorg C. Novel insights into structure and function of MRP8 (S100A8) and MRP14 (S100A9). Biochim Biophys Acta 1448 (1998) 200-211
3. Rammes A., Roth J., Goebeler M., Klempt M., Hartmann M., and Sorg C. Myeloid-related protein (MRP) 8 and MRP14, calcium-binding proteins of the S100 family, are secreted by activated monocytes via novel, tubulin-dependent pathway. J Biol Chem 272 (1997) 9496-9502
4. Guignard F., Mauel J., and Markert M. Identification and characterization of a novel human neutrophil protein related to the S100 family. Biochem J 309 (1995) 395-401
5. Schafer B.W., and Heizmann C.W. The S100 family of EF-hand calcium-binding proteins: functions and pathology. Trends Biochem Sci 21 (1996) 134-140
6. Ross K.F., and Herzberg M.C. Calprotectin expression by gingival epithelial cells. Infect Immun 69 (2001) 3248-3254
7. Lusitani D., Malawista S.E., and Montgomery R.R. Calprotectin, an abundant cytosolic protein from human polymorphonuclear leukocytes, inhibits the growth of Borrelia burgdorferi. Infect Immun 71 (2003) 4711-4716
8. Vogl T., Propper C., Hartmann M., et al. S100A12 is expressed exclusively by granulocytes and acts independently from MRP8 and MRP14. J Biol Chem 274 (1999) 25291-25296
9. Teigelkamp S., Bhardwaj R.S., Roth J., Meinardus H.G., Karas M., and Sorg C. Calcium-dependent complex assembly of the myeloic differentiation proteins MRP-8 and MRP-14. J Biol Chem 266 (1991) 13462-13467
10. Barthe C., Figarella C., Carrere J., and Guy-Crotte O. Identification of "cystic fibrosis protein" as a complex of two calcium-binding proteins present in human cells of myeloid origin. Biochim Biophys Acta 1096 (1991) 175-180
11. Hunter M.J., and Chazin W.J. High concentration expression and dimmer characterization of the S100 EF-hand proteins, migration inhibitory factor-related proteins 8 and 14. J Biol Chem 273 (1998) 12427-12435
12. Bhardwaj R., Zotz C., Zwadlo-Klarwasser G., et al. The calcium-binding proteins MRP8 and MRP14 form a membrane-associated heterodimer in a subset of monocytes/macrophages present in acute but absent in chronic inflammatory lesions. Eur J Immunol 22 (1992) 1891-1897
13. Ikemoto M., Tanaka T., Takai Y., Murayama H., Tanak K., and Fujita M. New ELISA system for myeloid-related protein complex (MRP8/14) and its clinical significance as a sensitive marker for inflammatory response associated with transplant rejection. Clin Chem 49 (2003) 594-600
14. Beckman J.S., and Koppenol W.H. Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and the ugly. Am J Physiol 271 (1996) C1424-C1437
15. Rubbo H., Darley-Usmar V., and Freeman B.A. Nitric oxide regulation of tissue free radical injury. Chem Res Toxicol 9 (1996) 809-820
16. Ischiropoulos H. Biological tyrosine nitration: a pathophysiological function of nitric oxide and reactive oxygen species. Arch Biochem Biophys 365 (1998) 1-11
17. Stamler J.S., Toone E.J., Lipton S.A., et al. (S)NO signals: translocation, regulation, and a consensus motif. Neuron 18 (1997) 691-696
18. Inoue K., Akaike T., Miyamoto Y., et al. Nitrosothiol formation catalyzed by ceruloplasmin: implication for cytoprotective mechanism in vivo. J Biol Chem 274 (1999) 27069-27075
19. Umezawa K., Akaike T., Fujii S., et al. Induction of nitric oxide synthesis and xanthine oxidase and their role in the antimicrobial mechanism against Salmonella typhimurium in mice. Infect Immun 65 (1997) 2932-2940
20. Towbin H., Staehelin T., and Gordon J. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc Natl Acad Sci U S A 76 (1979) 4350-4354
21. 15N nitrate in biological fluids. Anal Biochem 126 (1982) 131-138
22. Ikemoto M., Ishida A., Tsunekawa S., et al. Enzyme immunoassay of liver-type arginase and its potential clinical application. Clin Chem 39 (1993) 794-799
23. Nacken W., Sopalla C., Propper C., Sorg C., and Kerkhoff C. Biochemical characterization of the murine S100A9 (MRP14) protein suggests that it is functionally equivalent to its human counterpart despite its low degree of sequence homology. Eur J Biochem 267 (2000) 560-565
24. Nacken W., Roth J., Sorg C., and Kerkhoff C. S100A9/S100A8: myeloid representatives of the S100 protein family as prominent players in innate immunity. Microsc Res Tech 60 (2003) 569-580
25. Ryckman C., Vandal K., Rouleau P., Talbot M., and Tessier P.A. Proinflammatory activities of S100: proteins S100A8, S100A9, and S100A8/A9 induce neutrophil chemotaxis and adhesion. J Immunol 170 (2003) 3233-3242
26. Teigelkamp S., Bhardwaj R.S., Roth J., Meinardus-Hager G., Karas M., and Sorg C. Calcium-dependent complex assembly of the myeloic differentiation proteins MRP-8 and MRP-14. J Biol Chem 266 (1991) 13462-13467
27. 2+-dependent regulator protein in inflammatory process. J Mol Biol 316 (2002) 265-276
28. Robinson M.J., Tessier P., Poulsom R., and Hogg N. The S100 family heterodimer, MRP8/14, binds with high affinity to heparin and heparin sulfate glycosaminoglycans on endothelial cells. J Biol Chem 277 (2002) 3658-3665
29. 2+-binding proteins MRP8 and MRP14 binds arachidonic acid. FEBS Lett 408 (1997) 81-84
30. Kerkhoff C., Sorg C., Tandon N.N., and Nacken W. Interaction of S100A8/S100A9-arachidonic acid complexes with the scavenger receptor CD36 may facilitate fatty acid uptake by endothelial cells. Biochemistry 40 (2001) 241-248