IL-9 enhances growth of ICC, maintains network structure and strengthens rhythmicity of contraction in culture

Journal of Cellular and Molecular Medicine

Volumn 10, Issue 3, 2006, Pages 687-694

  Ye, Jing ^a   Zhu, Yaohui ^a   Khan, Waliul I ^a   Van Snick, Jacques ^b   Huizinga, Jan D ^a  

^a MCMASTER UNIVERSITY   (Canada)

^b UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

Author keywords

Auerbach's plexus; Explant culture; Growth factor; IL 9; Interstitial cell of Cajal (ICC); Myenteric plexus; Neurotransmission; Pacemaking; Smooth muscle cells; Ultrastructure

Indexed keywords

INTERLEUKIN 9;

ANIMAL; ARTICLE; CELL PROLIFERATION; CONNECTIVE TISSUE CELL; ELECTRON MICROSCOPY; GASTROINTESTINAL MOTILITY; GASTROINTESTINAL TRACT; IMMUNOHISTOCHEMISTRY; INFLAMMATION; INTESTINE INNERVATION; METABOLISM; MOUSE; MUSCLE CONTRACTION; PATHOLOGY; PHYSIOLOGY; STATISTICAL MODEL; TIME; ULTRASTRUCTURE;

ANIMALS; CELL PROLIFERATION; CONNECTIVE TISSUE CELLS; ENTERIC NERVOUS SYSTEM; GASTROINTESTINAL MOTILITY; GASTROINTESTINAL TRACT; IMMUNOHISTOCHEMISTRY; INFLAMMATION; INTERLEUKIN-9; MICE; MICROSCOPY, ELECTRON; MODELS, STATISTICAL; MUSCLE CONTRACTION; TIME FACTORS;

EID: 33845298296     PISSN: 15821838     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1582-4934.2006.tb00428.x     Document Type: Article

References (41)

1. Bernstein A, Forrester L, Reith AD, Dubreuil P, Rottapel R. The murine W/c-kit and Steel loci and the control of hematopoiesis. [Review]. Sem Hematol. 1991; 28: 138-42.
2. de Mesy Jensen KL, di Sant'Agnese PA. Large block embedding and "pop-off" technique for immunoelectron microscopy. Ultrastruct Pathol. 1992; 16: 51-9.
3. Der T, Bercik P, Donnelly G, Jackson T, Berezin I, Collins SM, Huizinga JD. Interstitial cells of Cajal and inflammation-induced motor dysfunction in the mouse small intestine. Gastroenterology 2000; 119: 1590-9.
4. Fujiki H, Kimura T, Minamiguchi H, Harada S, Wang J, Nakao M, Yokota S, Urata Y, Ueda Y, Yamagishi H, Sonoda Y. Role of human interleukin-9 as a megakaryocyte potentiator in culture. Exp Hematol 2002; 30: 1373-80.
5. Galli SJ, Kitamura Y. Genetically mast-cell-deficient W/Wv and Sl/Sld mice. Their value for the analysis of the roles of mast cells in biologic responses in vivo. Am J Pathol. 1987; 127: 191-198.
6. Glauert AM. Fixation, dehydration and embedding of biological specimens. Amsterdam. New York. Oxford: North-Holland Publishing Company, 1981.
7. Gounni AS, Hamid Q, Rahman SM, Hoeck J, Yang J, Shan L. IL-9-mediated induction of cotaxin1/CCL11 in human airway smooth muscle cells. J Immunol. 2004; 173: 2771-9.
8. Horvath VJ, Vittal H, Lorincz A, Chen H, meida-Porada G, Redelman D, Ordog T. Reduced stem cell factor links smooth myopathy and loss of interstitial cells of Cajal in murine diabetic gastroparesis. Gastroenterology 2006; 130: 759-70.
9. Horvath VJ, Vittal H, Ordog T. Reduced insulin and IGF-I signaling, not hyperglycemia, underlies the diabetes-associated depletion of interstitial cells of Cajal in the murine stomach. Diabetes 2005; 54: 1528-33.
10. Huizinga JD. Physiology and pathophysiology of the interstitial cell of Cajal: from bench to bedside. II. Gastric motility: lessons from mutant mice on slow waves and innervation. Am J Physiol Gastrointest Liver Physiol. 2001; 281: G1129-34.
11. Huizinga JD, Thuneberg L, Klüppel M, Malysz J, Mikkelsen HB, Bernstein A. The W/kit gene required for interstitial cells of Cajal and for intestinal pacemaker activity. Nature 1995; 373: 347-9.
12. Huizinga JD, Thuneberg L, Vanderwinden JM, Rumessen JJ. Interstitial cells of Cajal as pharmacological targets for gastrointestinal motility disorders. Trends Pharmacol Sci. 1997; 18: 393-403.
13. Huizinga JD, Zhu Y, Ye J, Molleman A. High-conductance chloride channels generate pacemaker currents in interstitial cells of Cajal. Gastroenterology 2002; 123: 1627-36.
14. Khan WI, Richard M, Akiho H, Blennerhasset PA, Humphreys NE, Grencis RK, Van Snick J, Collins SM. Modulation of intestinal muscle contraction by interleukin-9 (IL-9) or IL-9 neutralization: correlation with worm expulsion in murine nematode infections. Infect Immun. 2003; 71: 2430-8.
15. Klüppel M, Huizinga JD, Malysz J, Bernstein A. Developmental origin and Kit-dependent development of the interstitial cells of Cajal in the mammalian small intestine. Dev Dyn. 1998; 211: 60-71.
16. Leblanc N, Ledoux J, Saleh S, Sanguinetti A, Angermann J, O'Driscoll K, Britton F, Perrino BA, Greenwood IA. Regulation of calcium-activated chloride channels in smooth muscle cells: a complex picture is emerging. Can J Physiol Pharmacol. 2005; 83: 541-56.
17. Lee JCF. Intrinsic electrophysiological properties of interstitial cells of Cajal and smooth muscle cells. (Dissertation). McMaster University, 1999.
18. Maeda H, Yamagata A, Nishikawa S, Yoshinaga K, Kobayashi S, Nishi K. Requirement of c-kit for development of intestinal pacemaker system. Development 1992; 116: 369-75.
19. Matsuzawa S, Sakashita K, Kinoshita T, Ito S, Yamashita T, Koike K. IL-9 enhances the growth of human mast cell progenitors under stimulation with stem cell factor. J Immunol. 2003; 170: 3461-7.
20. McDermott JR, Bartram RE, Knight PA, Miller HR, Garrod DR, Grencis RK. Mast cells disrupt epithelial barrier function during enteric nematode infection. Proc Natl Acad Sci USA. 2003; 100: 7761-6.
21. d) mutant mouse small intestine. Neurogastroenterol Motil. 1998; 10: 1-17.
22. Ordog T, Takayama I, Cheung WK, Ward SM, Sanders KM. Remodeling of networks of interstitial cells of Cajal in a murine model of diabetic gastroparesis. Diabetes 2000; 49: 1731-9.
23. Reith AD, Bernstein A. Molecular Biology of the W and Steel loci. In: Genome Analysis Volume:3 Genes and Phenotypes. Cold Spring Harbour Laboratory Press, 1991; pp. 105-33.
24. Rich A, Miller SM, Gibbons SJ, Malysz J, Szurszewski JH, Farrugia G. Local presentation of Steel factor increases expression of c-kit immunoreactive interstitial cells of Cajal in culture. Am J Physiol Gastrointest Liver Physiol. 2003; 284: G313-20.
25. Rumessen JJ, Vanderwinden JM. Interstitial cells in the musculature of the gastrointestinal tract: Cajal and beyond. Int Rev Cytol. 2003; 229: 115-208.
26. Sanders KM. A case for interstitial cells of Cajal as pacemakers and mediators of neurotransmission in the gastrointestinal tract. [Review]. Gastroenterology 1996; 111: 492-515.
27. Soussi-Gounni A, Kontolemos M, Hamid Q. Role of IL-9 in the pathophysiology of allergic diseases. J Allergy Clin Immunol. 2001; 107: 575-82.
28. Temann UA, Geba GP, Rankin JA, Flavell RA. Expression of interleukin 9 in the lungs of transgenic mice causes airway inflammation, mast cell hyperplasia, and bronchial hyperresponsiveness. J Exp Med. 1998; 188: 1307-20.
29. Thuneberg L. Interstitial cells of Cajal in primary cultures of mouse small intestinal muscularis. Neurogastroenterol Motil. 1996; 8: 194.
30. Timmermans JP. Interstitial cells of Cajal: is their role in gastrointestinal function in view of therapeutic perspectives underestimated or exaggerated? Folia Morphol (Warsz). 2001; 60: 1-9.
31. Toda M, Tulic MK, Levitt RC, Hamid Q. A calcium-activated chloride channel (HCLCA1) is strongly related to IL-9 expression and mucus production in bronchial epithelium of patients with asthma. J Allergy Clin Immunol. 2002; 109: 246-50.
32. Vallance BA, Blennerhassett PA, Huizinga JD, Collins SM. Mast cell-independent impairment of host defense and muscle contraction in T. spiralis-infected W/W(V) mice. Am J Physiol Gastrointest Liver Physiol. 2001; 280: G640-8.
33. Vanderwinden JM, Rumessen JJ. Interstitial cells of Cajal in human gut and gastrointestinal disease. Microsc Res Tech. 1999; 47: 344-60.
34. Vetuschi A, Sferra R, Latella G, D'Angelo A, Caritti V, Zanninelli G, Continenza MA, Gaudio E. Smad3-null mice lack interstitial cells of Cajal in the colonic wall. Eur J Clin Invest. 2006; 36: 41-8.
35. Wang XY, Berezin I, Mikkelsen HB, Der T, Bercik P, Collins SM, Huizinga JD. Pathology of interstitial cells of Cajal in relation to inflammation revealed by ultrastructure but not immunohistochemistry. Am J Pathol. 2002; 160: 1529-40.
36. Wang XY, Vannucchi MG, Nieuwmeyer F, Ye J, Faussone-Pellegrini MS, Huizinga JD. Changes in interstitial cells of Cajal at the deep muscular plexus are associated with loss of distention-induced burst-type muscle activity in mice infected by Trichinella spiralis. Am J Pathol. 2005; 167: 437-53.
37. Ward SM, Burns AJ, Torihashi S, Sanders KM. Mutation of the proto-oncogene c-kit blocks development of interstitial cells and electrical rhythmicity in murine intestine. J Physiol. 1994; 94: 91-7.
38. Wiener Z, Falus A, Toth S. IL-9 increases the expression of several cytokines in activated mast cells, while the IL-9-induced IL-9 production is inhibited in mast cells of histamine-free transgenic mice. Cytokine 2004; 26: 122-30.
39. Zarate N, Wang XY, Tougas G, Anvari M, Birch D, Mearin F, Malagelada JR, Huizinga JD. Intramuscular interstitial cells of Cajal associated with mast cells survive nitrergic nerves in achalasia. Neurogastroenterol Motil. 2006; 18: 556-68.
40. Zhou Y, Dong Q, Louahed J, Dragwa C, Savio D, Huang M, Weiss C, Tomer Y, McLane MP, Nicolaides NC, Levitt RC. Characterization of a calcium-activated chloride channel as a shared target of Th2 cytokine pathways and its potential involvement in asthma. Am J Respir Cell Mol Biol. 2001; 25: 486-91.
41. Zhu Y, Mucci A, Huizinga JD. Inwardly rectifying chloride channel activity in intestinal pacemaker cells. Am J Physiol Gastrointest Liver Physiol. 2005; 288: G809-21.