Application of a validated stability-indicating densitometric thin-layer chromatographic method to stress degradation studies on moxifloxacin

Analytica Chimica Acta

Volumn 582, Issue 1, 2007, Pages 75-82

  Motwani, Sanjay K ^a   Khar, Roop K ^a   Ahmad, Farhan J ^a   Chopra, Shruti ^a   Kohli, K ^a   Talegaonkar, S ^a  

^a HAMDARD UNIVERSITY   (India)

Author keywords

High performance thin layer chromatography; Kinetics of degradation; Method validation; Moxifloxacin; pH rate profile; Stability indicating; Stress degradation

Indexed keywords

CHROMATOGRAPHIC ANALYSIS; CONCENTRATION (PROCESS); DEGRADATION; PH EFFECTS; REACTION KINETICS; SILICA GEL;

HIGH-PERFORMANCE THIN-LAYER CHROMATOGRAPHY; KINETICS OF DEGRADATION; METHOD VALIDATION; MOXIFLOXACIN; STABILITY INDICATING; STRESS DEGRADATION;

DRUG PRODUCTS;

MOXIFLOXACIN;

ACCURACY; ARTICLE; DENSITOMETRY; DRUG DEGRADATION; DRUG DETERMINATION; HEAT TREATMENT; HIGH PERFORMANCE THIN LAYER CHROMATOGRAPHY; HYDROLYSIS; PHOTODEGRADATION; PRIORITY JOURNAL; REPRODUCIBILITY;

AZA COMPOUNDS; CALIBRATION; CHROMATOGRAPHY, THIN LAYER; DENSITOMETRY; DRUG STABILITY; HYDROGEN-ION CONCENTRATION; KINETICS; QUINOLINES; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY;

EID: 33845296146     PISSN: 00032670     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.aca.2006.08.053     Document Type: Article

References (27)

1. Balfour J.A.B., and Wiseman L.R. Drugs 57 (1999) 363
2. Balfour J.A.B., and Lamb H.M. Drugs 59 (2000) 115
3. Pestova E., Millichap J.J., Noskin G.A., et al. J. Antimicrob. Chemother. 45 (2000) 583
4. Muijsers R.B.R., and Jarvis B. Drugs 62 (2002) 967
5. Chan K.P., Chu K.O., Lai W.W.K., Choy K.W., Wang C.C., Lam D.S.C., and Pang C.P. Anal. Biochem. 353 (2006) 30
6. Zhang C., Nightingale C.H., and Nicolau D.P. Zhongguo Yaoxue Zazhi 39 (2004) 699
7. Nguyen H.A., Grellet J., Boubakar B.B., Quentin C., and Saux M.C. J. Chromatogr. B 810 (2004) 77
8. Liang H., Kays M.B., and Sowinski K.M. J. Chromatogr. B 772 (2002) 53
9. Gonzalez J.A.O., Mochon M.C., and de la Rosa F.J.B. Microchim. Acta 151 (2005) 39
10. Lemoine T., Breilh D., Ducint D., Dubrez J., Jougon J., Velly J.F., and Saux M.C. J. Chromatogr. B 742 (2000) 247
11. Erk N. Anal. Bioanal. Chem. 378 (2004) 1351
12. Moller J.G., Stass H., Heinig R., and Blaschke G. J. Chromatogr. B 716 (1998) 325
13. Zhu B., Hu C., Jiang S., and Yin L. Zhongguo Kangshengsu Zazhi 27 (2002) 462
14. ICH-Q1A (R2), Stability Testing of New Drug Substances and Products, International Conference on Harmonization, Geneva, February 2003, http://www.ich.org/cache/compo/363-272-1.html#Q1A(R2).
15. Kulkarni S.P., and Amin P.D. J. Pharm. Biomed. Anal. 23 (2000) 983
16. Thoppil S.O., Cardoza R.M., and Amin P.D. J. Pharm. Biomed. Anal. 25 (2001) 15
17. Makhija S.N., and Vavia P.R. J. Pharm. Biomed. Anal. 25 (2001) 663
18. Kaul N., Agrawal H., Paradkar A.R., and Mahadik K.R. Anal. Chim. Acta 502 (2004) 31
19. Patravale V.B., D'Souza S., and Narkar Y. J. Pharm. Biomed. Anal. 25 (2001) 685
20. Ansari M.J., Ahmad S., Kohli K., Ali J., and Khar R.K. J. Pharm. Biomed. Anal. 39 (2005) 132
21. ICH-Q2 (R1), Validation of Analytical Procedures: Text and Methodology, International Conference on Harmonization, Geneva, November 2005, http://www.ich.org/LOB/media/MEDIA417.pdf.
22. Motwani S.K., Khar R.K., Ahmad F.J., Chopra S., Kohli K., Talegaonkar S., and Iqbal Z. Anal. Chim. Acta 576 (2006) 253
23. Chopra S., Ahmad F.J., Khar R.K., Motwani S.K., Mahdi S., Iqbal Z., and Talegaonkar S. Anal. Chim. Acta 577 (2006) 46
24. Indian Pharmacopoeia, vol. 2, Government of India, Ministry of Health and Family Welfare, 1996, p. A144.
25. Sethi P.D. High Performance Thin Layer Chromatography: Quantitative Analysis of Pharmaceutical Formulations (1996), CBS Publishers and Distributors, New Delhi
26. Garrett E.R., and Carper R.F. J. Am. Pharm. Assoc. Sci. 44 (1955) 515
27. Carstensen J.T., and Rhodes C.T. Drug Stability: Principles and Practices (2000), Marcel Dekker Inc., New York