Liquid chromatography/electrospray ionization tandem mass spectrometry validated method for the simultaneous quantification of sibutramine and its primary and secondary amine metabolites in human plasma and its application to a bioequivalence study

Rapid Communications in Mass Spectrometry

Volumn 20, Issue 23, 2006, Pages 3509-3521

  Jain, Deepak S ^a,b   Subbaiah, Gunta ^b   Sanyal, Mallika ^c   Shrivastav, Pranav S ^a   Pal, Usha ^a   Ghataliya, Shailesh ^b   Kakad, Abhijeet ^b   Patel, Heena ^b   Shah, Sapna ^b  

^a GUJARAT UNIVERSITY   (India)

^b Torrent Pharmaceuticals Ltd   (India)

^c ST XAVIER S COLLEGE   (India)

Author keywords

[No Author keywords available]

Indexed keywords

BIOMOLECULES; EXTRACTION; IONIZATION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PHASE SEPARATION; PLASMA (HUMAN);

BIOEQUIVALENCE STUDY; COEFFICIENT OF VARIANCE; ELECTROSPRAY IONIZATION TANDEM MASS SPECTROMETRY; HUMAN PLASMAS; INTERNAL STANDARDS; ITS APPLICATIONS; LIQUID CHROMATOGRAPHY ELECTROSPRAY; PRIMARY AND SECONDARY AMINE; SOLID-PHASE EXTRACTION; VALIDATED METHODS;

METABOLITES;

EID: 33845295148     PISSN: 09514198     EISSN: 10970231     Source Type: Journal    
DOI: 10.1002/rcm.2760     Document Type: Article

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