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Volumn 38, Issue 6, 2006, Pages 383-389

Frontline defense against the next pandemic: Antivirals for avian flu

Author keywords

Antiviral drugs; Bird flu; Drug resistance

Indexed keywords

AMANTADINE; DNA VACCINE; INFLUENZA VACCINE; OSELTAMIVIR; RIMANTADINE; SIALIDASE INHIBITOR; VIRUS VACCINE; ZANAMIVIR;

EID: 33845270426     PISSN: 02537613     EISSN: None     Source Type: Journal    
DOI: 10.4103/0253-7613.28203     Document Type: Review
Times cited : (1)

References (52)
  • 1
    • 0036514779 scopus 로고    scopus 로고
    • Updating the account lobal mortality of the 1918-1920 "Spanish" influenza pandemic
    • Johnson NP, Mueller J. Updating the account lobal mortality of the 1918-1920 "Spanish" influenza pandemic. Bull Hist Med 2002;76:105-15.
    • (2002) Bull Hist Med , vol.76 , pp. 105-115
    • Johnson, N.P.1    Mueller, J.2
  • 3
    • 33144461911 scopus 로고    scopus 로고
    • Avian influenza virus infections in humans
    • Wong SS, Yuen KY. Avian influenza virus infections in humans. Chest 2006;129:156-68.
    • (2006) Chest , vol.129 , pp. 156-168
    • Wong, S.S.1    Yuen, K.Y.2
  • 4
    • 23844499985 scopus 로고    scopus 로고
    • Origin and evolution of highly pathogenic H5N1 avian influenza in Asia
    • Sims LD, Domenech J, Benigno C, Kahn S, Kamata A, Lubroth J, et al. Origin and evolution of highly pathogenic H5N1 avian influenza in Asia. Vet Rec 2005;157:159-64.
    • (2005) Vet Rec , vol.157 , pp. 159-164
    • Sims, L.D.1    Domenech, J.2    Benigno, C.3    Kahn, S.4    Kamata, A.5    Lubroth, J.6
  • 5
    • 0037095571 scopus 로고    scopus 로고
    • Influenza A (H5N1) in Hong Kong: An overview
    • Tam JS. Influenza A (H5N1) in Hong Kong: An overview. Vaccine 2002;20:77-81.
    • (2002) Vaccine , vol.20 , pp. 77-81
    • Tam, J.S.1
  • 6
    • 0037847590 scopus 로고    scopus 로고
    • The next influenza pandemic: Lessons from Hong Kong
    • Shortridge KF, Peiris JS, Guan Y. The next influenza pandemic: Lessons from Hong Kong. J Appl Microbiol 2003;94:70-9.
    • (2003) J Appl Microbiol , vol.94 , pp. 70-79
    • Shortridge, K.F.1    Peiris, J.S.2    Guan, Y.3
  • 7
    • 10744229587 scopus 로고    scopus 로고
    • Transmission of H7N7 avian influenza A virus to human beings during a large outbreak in commercial poultry farms in the Netherlands
    • Koopmans M, Wilbrink B, Conyn M, Natrop G, van der Nat H, Vennema H, et al. Transmission of H7N7 avian influenza A virus to human beings during a large outbreak in commercial poultry farms in the Netherlands. Lancet 2004;363:587-93.
    • (2004) Lancet , vol.363 , pp. 587-593
    • Koopmans, M.1    Wilbrink, B.2    Conyn, M.3    Natrop, G.4    Van Der Nat, H.5    Vennema, H.6
  • 8
    • 33749596400 scopus 로고    scopus 로고
    • [accessed: 2006 May 2]. Available from
    • World Health Organisation. Avian Influenza- frequently asked questions. [accessed: 2006 May 2]. Available from: http://www.who.int/csr/disease/ avian_influenza/avian_faqs/en/index.html
    • Avian Influenza- Frequently Asked Questions
  • 10
    • 30744450242 scopus 로고    scopus 로고
    • The birds are coming: Are we ready?
    • Jameel S. The birds are coming: Are we ready? Indian J Med Res 2005;122:277-81.
    • (2005) Indian J Med Res , vol.122 , pp. 277-281
    • Jameel, S.1
  • 15
    • 33845237891 scopus 로고    scopus 로고
    • [accessed: 2006 May 3]. Available from
    • Oseltamivir. [accessed: 2006 May 3]. Available from: http://en.wikipedia. org/wiki/oseltamivirf
    • Oseltamivir
  • 16
    • 0031916471 scopus 로고    scopus 로고
    • Identification of GS 4104 as an orally bioavailable prodrug of the influenza virus neuraminidase inhibitor GS 4071
    • Li W, Escarpe PA, Eisenberg EJ, Cundy KC, Sweet C, Jakeman KJ, et al. Identification of GS 4104 as an orally bioavailable prodrug of the influenza virus neuraminidase inhibitor GS 4071. Antimicrob Agents Chemother 1998;42:647-53.
    • (1998) Antimicrob Agents Chemother , vol.42 , pp. 647-653
    • Li, W.1    Escarpe, P.A.2    Eisenberg, E.J.3    Cundy, K.C.4    Sweet, C.5    Jakeman, K.J.6
  • 17
    • 0031919227 scopus 로고    scopus 로고
    • Oral administration of a prodrug of the influenza virus neuraminidase inhibitor GS 4071 protects mice and ferrets against influenza infection
    • Mendel DB, Tai CY, Escarpe PA, Li W, Sidwell RW, Huffman JH, et al. Oral administration of a prodrug of the influenza virus neuraminidase inhibitor GS 4071 protects mice and ferrets against influenza infection. Antimicrob Agents Chemother 1998;42:640-6.
    • (1998) Antimicrob Agents Chemother , vol.42 , pp. 640-646
    • Mendel, D.B.1    Tai, C.Y.2    Escarpe, P.A.3    Li, W.4    Sidwell, R.W.5    Huffman, J.H.6
  • 18
    • 0033651178 scopus 로고    scopus 로고
    • The neuraminidase inhibitor GS4104 (oseltamivir phosphate) is efficacious against A/ Hong Kong/156/97 (H5N1) and A/Hong Kong/1074/99 (H9N2) influenza viruses
    • Leneva IA, Roberts N, Govorkova EA, Goloubeva OG, Webster RG. The neuraminidase inhibitor GS4104 (oseltamivir phosphate) is efficacious against A/ Hong Kong/156/97 (H5N1) and A/Hong Kong/1074/99 (H9N2) influenza viruses. Antiviral Res 2000;48:101-15.
    • (2000) Antiviral Res , vol.48 , pp. 101-115
    • Leneva, I.A.1    Roberts, N.2    Govorkova, E.A.3    Goloubeva, O.G.4    Webster, R.G.5
  • 19
    • 0034801450 scopus 로고    scopus 로고
    • Comparison of efficacies of RWJ-270201, zanamivir and oseltamivir against H5N1, H9N2, and other avian influenza viruses
    • Govorkova EA, Leneva IA, Goloubeva OG, Bush K, Webster RG. Comparison of efficacies of RWJ-270201, zanamivir and oseltamivir against H5N1, H9N2, and other avian influenza viruses. Antimicrob Agents Chemother 2001;45:2723-32.
    • (2001) Antimicrob Agents Chemother , vol.45 , pp. 2723-2732
    • Govorkova, E.A.1    Leneva, I.A.2    Goloubeva, O.G.3    Bush, K.4    Webster, R.G.5
  • 21
    • 0003304192 scopus 로고    scopus 로고
    • Tolerability and pharmacokinetics of the influenza neuraminidase inhibitor Ro 64-0802 (GS4071) following oral administration of the prodrug Ro 64-0796 (GS4104) to healthy male volunteers
    • Program and Abstracts of the; 1997 Sep 27-28; Washington, DC
    • Wood ND, Aitken M, Sharp S, Evison H. Tolerability and pharmacokinetics of the influenza neuraminidase inhibitor Ro 64-0802 (GS4071) following oral administration of the prodrug Ro 64-0796 (GS4104) to healthy male volunteers. Program and abstracts of the 37th Interscience Conference on Antimicrobial Agents and Chemotherapy; 1997 Sep 27-28; Washington, DC; 1997. p. 25.
    • (1997) 37th Interscience Conference on Antimicrobial Agents and Chemotherapy , pp. 25
    • Wood, N.D.1    Aitken, M.2    Sharp, S.3    Evison, H.4
  • 24
    • 0345516152 scopus 로고    scopus 로고
    • Efficacy and tolerability of oral GS4104 for early treatment of experimental influenza in humans
    • (abstract). Sept 28; Abstr 14
    • Hayden FG, Lobo M, Treanor JJ. Efficacy and tolerability of oral GS4104 for early treatment of experimental influenza in humans (abstract). 37th ICAAC Program Addendum: 1997 Sept 28; Abstr 14.
    • (1997) 37th ICAAC Program Addendum
    • Hayden, F.G.1    Lobo, M.2    Treanor, J.J.3
  • 25
    • 33845262744 scopus 로고    scopus 로고
    • Oseltamivir
    • Lacy CF, Armstrong LL, Goldman M, Lance LL, editors. Hudson, Ohio: Lexi-Comp Inc publication
    • Oseltamivir. In: Lacy CF, Armstrong LL, Goldman M, Lance LL, editors. Lexi-Comp's Drug Information Handbook. 11th ed. Hudson, Ohio: Lexi-Comp Inc publication; 2003. p.1036-37.
    • (2003) Lexi-Comp's Drug Information Handbook. 11th Ed. , pp. 1036-1037
  • 26
    • 0037066803 scopus 로고    scopus 로고
    • Prevention and control of influenza: Recommendations of the Advisory Committee on Immunization Practices
    • CDC: Centers for Disease Control and Prevention
    • CDC: Centers for Disease Control and Prevention. Prevention and control of influenza: recommendations of the Advisory Committee on Immunization Practices. MMWR 2002; 51:15-31.
    • (2002) MMWR , vol.51 , pp. 15-31
  • 28
    • 0035077692 scopus 로고    scopus 로고
    • Efficacy of zanamivir against avian influenza a viruses that possess genes encoding H5N1 internal proteins and are pathogenic in mammals
    • Leneva IA, Goloubeva O, Fenton RJ, Tisdale M, Webster RG. Efficacy of zanamivir against avian influenza A viruses that possess genes encoding H5N1 internal proteins and are pathogenic in mammals. Antimicrob Agents Chemother 2001;45:1216-24.
    • (2001) Antimicrob Agents Chemother , vol.45 , pp. 1216-1224
    • Leneva, I.A.1    Goloubeva, O.2    Fenton, R.J.3    Tisdale, M.4    Webster, R.G.5
  • 30
    • 0033998478 scopus 로고    scopus 로고
    • Pharmacokinetics and tolerability of a single inhaled dose of zanamivir in children
    • Peng AW, Hussey EK, Rosolowski B, Blumer JL. Pharmacokinetics and tolerability of a single inhaled dose of zanamivir in children. Curr Ther Res 2000;61:36-46.
    • (2000) Curr Ther Res , vol.61 , pp. 36-46
    • Peng, A.W.1    Hussey, E.K.2    Rosolowski, B.3    Blumer, J.L.4
  • 31
    • 0032996541 scopus 로고    scopus 로고
    • Pharmacokinetics of zanamivir after intravenous, oral, inhaled or intranasal administration to healthy volunteers
    • Cass LM, Efthymiopoulos C, Bye A. Pharmacokinetics of zanamivir after intravenous, oral, inhaled or intranasal administration to healthy volunteers. Clin Pharmacokinet 1999;36:1-11.
    • (1999) Clin Pharmacokinet , vol.36 , pp. 1-11
    • Cass, L.M.1    Efthymiopoulos, C.2    Bye, A.3
  • 33
    • 0032512327 scopus 로고    scopus 로고
    • Randomized trial of efficacy and safety of inhaled zanamivir in treatment of influenza A and B virus infections
    • The MIST study group
    • The MIST study group. Randomized trial of efficacy and safety of inhaled zanamivir in treatment of influenza A and B virus infections. Lancet 1998;353:1877-81.
    • (1998) Lancet , vol.353 , pp. 1877-1881
  • 34
    • 0037017077 scopus 로고    scopus 로고
    • Drugs for non-HIV viral infections
    • Drugs for non-HIV viral infections. Med Lett Drugs Ther 2002;44:9-16.
    • (2002) Med Lett Drugs Ther , vol.44 , pp. 9-16
  • 35
    • 0033678542 scopus 로고    scopus 로고
    • Efficacy and safety of inhaled zanamivir for the treatment of influenza in patients with asthma or chronic obstructive pulmonary disease. A double-blind, randomised, placebo-controlled, multicentre study
    • Murphy KR, Eivindson A, Pauksens K, William, Tellier G, Watts R, et al. Efficacy and safety of inhaled zanamivir for the treatment of influenza in patients with asthma or chronic obstructive pulmonary disease. A double-blind, randomised, placebo-controlled, multicentre study. Clin Drug Invest 2000;20:337-49.
    • (2000) Clin Drug Invest , vol.20 , pp. 337-349
    • Murphy, K.R.1    Eivindson, A.2    Pauksens, K.3    William4    Tellier, G.5    Watts, R.6
  • 36
    • 0034594874 scopus 로고    scopus 로고
    • Respiratory distress associated with zanamivir
    • Williamson JC, Pegram PS. Respiratory distress associated with zanamivir. N Engl J Med 2000;342:661-2.
    • (2000) N Engl J Med , vol.342 , pp. 661-662
    • Williamson, J.C.1    Pegram, P.S.2
  • 37
    • 33845235718 scopus 로고    scopus 로고
    • Zanamivir
    • Lacy CF, Armstrong LL, Goldman M, Lance LL, editors. Hudson, Ohio: Lexi-Comp Inc publication
    • Zanamivir. In: Lacy CF, Armstrong LL, Goldman M, Lance LL, editors. Lexi-Comp's Drug Information Handbook. 11th ed. Hudson, Ohio: Lexi-Comp Inc publication; 2003. p.1463-64.
    • (2003) Lexi-Comp's Drug Information Handbook. 11th Ed. , pp. 1463-1464
  • 38
    • 0033054511 scopus 로고    scopus 로고
    • Coadministration of orally inhaled zanamivir with inactivated trivalent influenza vaccine does not adversely affect the production of antihaemagglutinin antibodies in the serum of healthy volunteers
    • Webster A, Boyce M, Edmundson S, Miller I. Coadministration of orally inhaled zanamivir with inactivated trivalent influenza vaccine does not adversely affect the production of antihaemagglutinin antibodies in the serum of healthy volunteers. Clin Pharmacokinet 1999;36:51-8.
    • (1999) Clin Pharmacokinet , vol.36 , pp. 51-58
    • Webster, A.1    Boyce, M.2    Edmundson, S.3    Miller, I.4
  • 40
    • 25444501243 scopus 로고    scopus 로고
    • Neuraminidase inhibitors for influenza
    • Moscona A. Neuraminidase inhibitors for influenza. N Eng J Med 2005;353:1363-73.
    • (2005) N Eng J Med , vol.353 , pp. 1363-1373
    • Moscona, A.1
  • 41
    • 25444432780 scopus 로고    scopus 로고
    • Avian influenza a (H5N1) infection in humans
    • The Writing Committee of the World Health Organization (WHO) Consultation on Human Influenza A/H5
    • The Writing Committee of the World Health Organization (WHO) Consultation on Human Influenza A/H5. Avian influenza A (H5N1) infection in humans. N Eng J Med 2005;353:1374-85.
    • (2005) N Eng J Med , vol.353 , pp. 1374-1385
  • 43
    • 0032526697 scopus 로고    scopus 로고
    • Drug design against a shifting target: A structural basis for resistance to inhibitors in a variant of influenza virus neuraminidase
    • Varghese JN, Smith PW, Sollis SL, Blick TJ, Sahasrabudhe A, McKimm-Breschkin JL, et al. Drug design against a shifting target: A structural basis for resistance to inhibitors in a variant of influenza virus neuraminidase. Structure 1998;6:735-46.
    • (1998) Structure , vol.6 , pp. 735-746
    • Varghese, J.N.1    Smith, P.W.2    Sollis, S.L.3    Blick, T.J.4    Sahasrabudhe, A.5    McKimm-Breschkin, J.L.6
  • 44
    • 29144433925 scopus 로고    scopus 로고
    • Oseltamivir Resistance - Disabling our influenza defenses
    • Moscona A. Oseltamivir Resistance - disabling our influenza defenses. N Eng J Med 2005;353:2633-6.
    • (2005) N Eng J Med , vol.353 , pp. 2633-2636
    • Moscona, A.1
  • 45
    • 31344450870 scopus 로고    scopus 로고
    • Making Better Influenza Virus Vaccines
    • Palese P. Making Better Influenza Virus Vaccines. Emerg Infect Dis 2006;12:61-5.
    • (2006) Emerg Infect Dis , vol.12 , pp. 61-65
    • Palese, P.1
  • 46
    • 33749081161 scopus 로고    scopus 로고
    • Influenza vaccine 2005-2006
    • Influenza vaccine 2005-2006. The Medical Letter 2005;47:85.
    • (2005) The Medical Letter , vol.47 , pp. 85
  • 47
    • 33845267286 scopus 로고    scopus 로고
    • Tables for Influenza: January 2006
    • [accessed: 2006 May 2]. obtained from
    • Tables for Influenza: January 2006. [accessed: 2006 May 2]. Medscape Infectious Diseases 2006;8(1) obtained from www.medscape.com.
    • (2006) Medscape Infectious Diseases , vol.8 , Issue.1
  • 48
    • 26044458556 scopus 로고    scopus 로고
    • Avian influenza virus: Prospects for prevention and control by vaccination
    • Lee CW, Suarez DL. Avian influenza virus: Prospects for prevention and control by vaccination. Anim Health Res Rev 2005;1:1-15.
    • (2005) Anim Health Res Rev , vol.1 , pp. 1-15
    • Lee, C.W.1    Suarez, D.L.2
  • 49
    • 0347104486 scopus 로고    scopus 로고
    • Recent developments in avian influenza research, epidemiology and immunoprophylaxis
    • Tollis M, Di Trani L. Recent developments in avian influenza research, epidemiology and immunoprophylaxis. Vet J 2002;164:202-15.
    • (2002) Vet J , vol.164 , pp. 202-215
    • Tollis, M.1    Di Trani, L.2
  • 50
    • 3843071042 scopus 로고    scopus 로고
    • Generation of reassortant influenza vaccines by reverse genetics that allows utilization of a DIVA (Differentiating Infected from Vaccinated Animals) Strategy for the control of avian influenza
    • Lee CW, Seene DA, Suarez DL. Generation of reassortant influenza vaccines by reverse genetics that allows utilization of a DIVA (Differentiating Infected from Vaccinated Animals) Strategy for the control of avian influenza. Vaccine 2004;22:3175-81.
    • (2004) Vaccine , vol.22 , pp. 3175-3181
    • Lee, C.W.1    Seene, D.A.2    Suarez, D.L.3
  • 51
    • 0141789657 scopus 로고    scopus 로고
    • Reverse genetics for the control of avian influenza
    • 203
    • Neumann G, Hatta M, Kawaoka Y. Reverse genetics for the control of avian influenza. Avian Dis 203;47:882-7.
    • Avian Dis , vol.47 , pp. 882-887
    • Neumann, G.1    Hatta, M.2    Kawaoka, Y.3


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