Qualitative and quantitative measurements of hydrogen bond mediated scalar couplings in acyclic 1,3-diols

Organic Letters

Volumn 8, Issue 23, 2006, Pages 5321-5323

  Loening, Nikolaus M ^a   Anderson, Carolyn E ^b   Iskenderian, Wendy S ^b   Anderson, Christopher D ^d   Rychnovsky, Scott D ^d   Barfield, Michael ^c   O'Leary, Daniel J ^b  

^a LEWIS AND CLARK COLLEGE   (United States)

^b POMONA COLLEGE   (United States)

^c University of Arizona   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALIPHATIC HYDROCARBON;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; HYDROGEN BOND;

HYDROCARBONS, ACYCLIC; HYDROGEN BONDING; MOLECULAR STRUCTURE;

EID: 33845261362     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol062121v     Document Type: Article

References (16)

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9. Elaborate ways to more accurately include relaxation in the damping of the signal can be derived, but such approaches are fraught with uncertainties because of the multiple relaxation times involved and the susceptibility of such analyses to experimental artifacts. Consequently, in fitting the data, we focus on the sinusoidal component due to the coupling constant and lump all other relaxation and experimental artifacts together as a single exponential damping term. By focusing on where the signal changes sign (which can only be due to the coupling term), we sidestep the problem of trying to define multiple relaxation terms and are able to accurately extract the coupling constant.
10. Details of the calculations are provided in the Supporting Information.
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