Synthesis and biological evaluation of pyridooxazine-tetrahydroisoquinoline derivatives as MDR modulators

Chemistry Letters

Volumn 35, Issue 9, 2006, Pages 1010-1011

  Ma, Chen ^a   Liu, Shao Jie ^a   Xin, Liang ^a   Zhang, Qun ^a   Ding, Kai ^a   Falck, J R ^b   Shin, Dong Soo ^c  

^a SHANDONG UNIVERSITY   (China)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^c Changwon National University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 33845260990     PISSN: 03667022     EISSN: None     Source Type: Journal    
DOI: 10.1246/cl.2006.1010     Document Type: Article

References (24)

1. a) Q. Zhang, G. Tu, Y. Zhao, T. Cheng, Tetrahedron 2002, 58, 6795.
2. b) S. Batra, Y. A. Sabnis, P. J. Rosenthal, M. A. Avery, Bioorg. Med. Chem. 2003, 11, 2293.
3. c) Y. Takeshi, Chem. Pharm. Bull. 1999, 47, 22.
4. d) V. Vecchietti, G. D. Clarke, R. Colle, J. Med. Chem. 1992, 35, 2970.
5. e) S. Kirschbaum, H. Waldmann, J. Org. Chem. 1998, 63, 4936.
6. f) L. Carrillo, D. Badia, E. Dominguez, E. Aankabe, J. Org. Chem. 1999, 64, 1115.
7. g) J. E. Van Muijlwijk-Koezen, H. Timmerman, R. Link, H. Vander Goot, A. P. Ijzerman, J. Med. Chem. 1998, 41, 3987.
8. h) Q. Zeng, Y. Kwok, S. M. Kerwin, V. Mangold, L. H. Hurley, J. Med. Chem. 1998, 41, 4273.
9. a) M. A. Mctigue, D. W. Williams, J. A. Tainer, J. Mol. Bid. 1995, 21, 246.
10. b) N. J. O'Reilly, W. S. Derwin, H.-C. Lin, Synthesis 1990, 550.
11. c) Y. Takeshi, Chem. Pharm. Bull. 1999, 47, 22.
12. d) V. Vecchietti, G. D. Clarke, R. Colle, J. Med. Chem. 1992, 55, 2970.
13. e) S. Kirschbaum, H. Waldmann, J. Org. Chem. 1998, 63, 4936.
14. f) L. Carrillo, D. Badia, E. Dominguez, E. Aankabe, J. Org. Chem. 1999, 64, 1115.
15. a) R. D. Larsen, R. A. Reamer, E. G. Corley, P. Davis, E. J. Grabowski, P. J. Reider, I. Shinkai, J. Org. Chem. 1991, 56, 6034.
16. b) M. Cushman, D. Nagarathnam, D. Gopal, H. M. He, C. M. Lin, E. Hamel, J. Med. Chem. 1992, 35, 2293.
17. c) R. D. Clark, J. Org. Chem. 1989, 54, 1174.
18. d) S. Kirschbaum, H. Waldmann, J. Org. Chem. 1998, 63, 4936.
19. e) A. Pezzella, G. Prota, Tetrahedron Lett. 2002, 43, 6719.
20. f) C. C. Silveira, C. R. Bernardi, A. L. Braga, T. S. Kaufman, Tetrahedron Lett. 2003, 44, 6137.
21. A. Tulpule, A. Sherrod, D. Dharmapala, L. Young, B. Espina, M. Byron, M. N. Sanchez, P. S. Gill, A. M. Levine, Leuk. Res. 2002, 26, 121.
22. C. Ma, S.-D. Cho, J. R. Falck, D.-S. Shin, Heterocycles 2004, 63, 75.
23. S.-D. Cho, Y.-D. Park, J.-J. Kim, S.-G. Lee, C. Ma, S.-Y. Song, W.-H. Joo, J. R. Falck, M. Shiro, D.-S. Shin, Y.-J. Yoon, J. Org. Chem. 2003, 68, 7918.
24. J. Robert, C. Jarry, J. Med. Chem. 2003, 46, 4805.